Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress 2023 EHA Congress 2023 ASCO Annual Meeting
Clinical Collections
Advances in Alzheimer’s

At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.
ADVANCED SEARCH
Log in
Top
Digestive Diseases and Sciences
Literature
1.
Giuffrida P, Corazza GR, Di Sabatino A. Old and new lymphocyte players in inflammatory bowel disease. Dig Dis Sci. 2018;63:277–288.CrossRefPubMed
2.
Goldberg R, Prescott N, Lord GM, MacDonald TT, Powell N. The unusual suspects–innate lymphoid cells as novel therapeutic targets in IBD. Nat Rev Gastroenterol Hepatol. 2015;12:271–283.CrossRefPubMed
3.
Treiner E. Mucosal-associated invariant T cells in inflammatory bowel diseases: bystanders, defenders, or offenders? Front Immunol. 2015;6:27.PubMedPubMedCentral
4.
Andreu-Ballester JC, Amigó-García V, Catalán-Serra I, et al. Deficit of gammadelta T lymphocytes in the peripheral blood of patients with Crohn’s disease. Dig Dis Sci. 2011;56:2613–2622.CrossRefPubMed
5.
Catalan Serra I, Bruland T, Sandvik A, et al. Gammadelta T cells deficiency in the peripheral blood of patients with Crohn’s disease: inverse correlation with clinical and endoscopical activity. Gastroenterology. 2017;5(Suppl1):S616.CrossRef
6.
Mann ER, McCarthy NE, Peake ST, et al. Skin- and gut-homing molecules on human circulating γδT cells and their dysregulation in inflammatory bowel disease. Clin Exp Immunol. 2012;170:122–130.CrossRefPubMedPubMedCentral
7.
McCarthy NE, Hedin CR, Sanders TJ, et al. Azathioprine therapy selectively ablates human Vδ2+ T cells in Crohn’s disease. J Clin Invest. 2015;125(3215–25):41.
8.
Kadivar M, Petersson J, Svensson L, Marsal J. CD8αβ+ γδT cells: a novel T cell subset with a potential role in inflammatory bowel disease. J Immunol. 2016;197:4584–4592.CrossRefPubMed
9.
Deusch K, Lüling F, Reich K, Classen M, Wagner H, Pfeffer K. A major fraction of human intraepithelial lymphocytes simultaneously expresses the gamma/delta T cell receptor, the CD8 accessory molecule and preferentially uses the V delta 1 gene segment. Eur J Immunol. 1991;21:1053–1059.CrossRefPubMed
10.
Chien YH, Meyer C, Bonneville M. γδT cells: first line of defense and beyond. Annu Rev Immunol. 2014;32:121–155.CrossRefPubMed
11.
12.
Inagaki-Ohara K, Chinen T, Matsuzaki G, et al. Mucosal T cells bearing TCR gammadelta play a protective role in intestinal inflammation. J Immunol. 2004;173:1390–1398.CrossRefPubMed
13.
Hoffmann JC, Pawlowski NN, Grollich K, Loddenkemper C, Zeitz M, Kühl AA. Gammadelta T lymphocytes: a new type of regulatory T cells suppressing murine 2,4,6-trinitrobenzene sulphonic acid [TNBS]-induced colitis. Int J Colorectal Dis. 2008;23:909–920.CrossRefPubMed
14.
Andreu-Ballester JC, Garcia-Ballesteros C, Amigo V, et al. Microsporidia and its relation to Crohn’s disease. A retrospective study. PLoS One. 2013;8:e62107.CrossRefPubMedPubMedCentral
15.
16.
Li J, Ueno A, Iacucci M, et al. Crossover subsets of CD4(+) T lymphocytes in the intestinal lamina propria of patients with Crohn’s disease and ulcerative colitis. Dig Dis Sci. 2017;62:2357–2368.CrossRefPubMed
17.
Alfen JS, Larghi P, Facciotti F, et al. Intestinal IFN-γ-producing type 1 regulatory T cells coexpress CCR5 and programmed cell death protein 1 and downregulate IL-10 in the inflamed guts of patients with inflammatory bowel disease. J Allergy Clin Immunol. 2018 Jan 31. (Epub ahead of print).
18.
Paroni M, Magarotto A, Tartari S, et al. Uncontrolled IL-17 production by intraepithelial lymphocytes in a case of non-IPEX autoimmune enteropathy. Clin Transl Gastroenterol. 2016;7:e182.CrossRefPubMedPubMedCentral
19.
Backert I, Koralov SB, Wirtz S, et al. STAT3 activation in Th17 and Th22 cells controls IL-22-mediated epithelial host defense during infectious colitis. J Immunol. 2014;193:3779–3791.CrossRefPubMed
Metadata
Title
Gammadelta T Cells: Unconventional T Cells Involved in IBD Pathogenesis
Authors
Ignacio Catalan-Serra
Juan Carlos Andreu-Ballester
Torunn Bruland
Arne Kristian Sandvik
Publication date
01-07-2018
Publisher
Springer US
Published in
Digestive Diseases and Sciences / Issue 7/2018
Print ISSN: 0163-2116
Electronic ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-018-5059-7

Other articles of this Issue 7/2018

Digestive Diseases and Sciences 7/2018 Go to the issue

Editorial

Painful and Painless Constipation: All Roads Lead to (A Change in) Rome

Editorial

GI Bleeding Risk of DOACs Versus Warfarin: Is Newer Better?

Original Article

Health Maintenance Documentation Improves for Veterans with IBD Using a Template in the Computerized Patient Record System

Original Article

Natural Language Processing Accurately Calculates Adenoma and Sessile Serrated Polyp Detection Rates

Original Article

Locations and Mucosal Lesions Responsible for Major Gastrointestinal Bleeding in Patients on Warfarin or Dabigatran

Original Article

Long-Term Follow-Up Study of Liver-Related Outcome After Bilio-Pancreatic Diversion in Patients with Initial, Significant Liver Damage

ACC 2024 Congress Coverage

Heart Failure Video

Year in Review: Heart failure and cardiomyopathies

Watch now

Watch this official video from ACC.24. Dr. Biykem Bozkurt discuss last year's major advances in heart failure and cardiomyopathies.

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

16-04-2024 Type 2 Diabetes News

Incentivised to exercise

11-04-2024 Lifestyle Modifications News

New intervention for STEMI-related cardiogenic shock

10-04-2024 Myocardial Infarction News

» View more highlights on the ACC 2024 congress hub page

Image Credits