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Digestive Diseases and Sciences
Published in: Digestive Diseases and Sciences 11/2017

01-11-2017 | Editorial

Long Non-coding RNAs in Gastric Cancer: A True Relationship or miR Chance?

Author: Konstantinos Mavridis

Published in: Digestive Diseases and Sciences | Issue 11/2017

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Excerpt

Long non-coding RNAs (lncRNAs) are gradually drawing the attention of the cancer research community due to their pivotal involvement in tumorigenesis and tumor progression [1]. These non-protein coding, >200 nucleotides long transcripts are aberrantly expressed in the majority of human malignancies, including gastric cancer (GC) [1, 2]. …
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Li T, Meng X, Yang W, et al. Long noncoding RNA PVT1 acts as a “sponge” to inhibit microRNA-152 in gastric cancer cells. Dig Dis Sci. (Epub ahead of print). doi:10.​1007/​s10620-017-4508-z.
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Cui M, You L, Ren X, et al. Long non-coding RNA PVT1 and cancer. Biochem Biophys Res Commun. 2016;471:10–14.CrossRefPubMed
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Chen Y, Song Y, Wang Z, et al. Altered expression of MiR-148a and MiR-152 in gastrointestinal cancers and its clinical significance. J Gastrointest Surg. 2010;14:1170–1179.CrossRefPubMed
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Zhai R, Kan X, Wang B, et al. miR-152 suppresses gastric cancer cell proliferation and motility by targeting CD151. Tumour Biol. 2014;35:11367–11373.CrossRefPubMed
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Song B, Guan Z, Liu F, et al. Long non-coding RNA HOTAIR promotes HLA-G expression via inhibiting miR-152 in gastric cancer cells. Biochem Biophys Res Commun. 2015;464:807–813.CrossRefPubMed
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Noda M, Hattori T, Kimura T, et al. Expression of fibroblast growth factor 2 mRNA in early and advanced gastric cancer. Acta Oncol. 1997;36:695–700.CrossRefPubMed
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Du L, Xiao X, Wang C, et al. Human leukocyte antigen-G is closely associated with tumor immune escape in gastric cancer by increasing local regulatory T cells. Cancer Sci. 2011;102:1272–1280.CrossRefPubMed
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Scorilas A, Mavridis K. Predictions for the future of kallikrein-related peptidases in molecular diagnostics. Expert Rev Mol Diagn. 2014;14:713–722.CrossRefPubMed
Metadata
Title
Long Non-coding RNAs in Gastric Cancer: A True Relationship or miR Chance?
Author
Konstantinos Mavridis
Publication date
01-11-2017
Publisher
Springer US
Published in
Digestive Diseases and Sciences / Issue 11/2017
Print ISSN: 0163-2116
Electronic ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-017-4537-7

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