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Published in: Digestive Diseases and Sciences 9/2016

01-09-2016 | Stanford Multidisciplinary Seminars

Self-Limited Sepsis Syndrome Following Fecal Microbiota Therapy for Refractory C. difficile Infection

Authors: Sundeep Singh, Emily Jing, Neil Stollman

Published in: Digestive Diseases and Sciences | Issue 9/2016

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Excerpt

A 56-year-old woman who had denied any prior travel or sick contacts was initially evaluated in the Emergency Department with complaints of 7 days of watery, non-bloody diarrhea, associated with 1 day of nausea and vomiting. She reported having 8–10 bowel movements per day, a frequency that was progressively increasing. One month prior to admission, she had been treated with 10 days of amoxicillin–clavulanate for bacterial sinusitis. Three days prior to admission, she took two doses of loperamide at home without any decrease in the frequency of bowel movements. Ciprofloxacin had been prescribed the day prior to admission without any clinical improvement. She had no significant past medical or surgical history, except for mild depression that was treated with sertraline. …
Literature
1.
go back to reference Lessa FC, Mu Y, Bamberg WM, et al. Burden of Clostridium difficile infection in the United States. NEJM. 2015;372:825–834.CrossRefPubMed Lessa FC, Mu Y, Bamberg WM, et al. Burden of Clostridium difficile infection in the United States. NEJM. 2015;372:825–834.CrossRefPubMed
2.
go back to reference Beran V, Chmelar D, Vobejdova J, et al. Sensitivity to antibiotics of Clostridium difficile toxigenic nosocomial strains. Folia Microbiol. 2014;59:209–215.CrossRef Beran V, Chmelar D, Vobejdova J, et al. Sensitivity to antibiotics of Clostridium difficile toxigenic nosocomial strains. Folia Microbiol. 2014;59:209–215.CrossRef
3.
go back to reference Neal MD, Alverdy JC, Hall DE, et al. Diverting loop ileostomy and colonic lavage: an alternative to total abdominal colectomy for the treatment of severe complicated Clostridium difficile associated disease. Ann Surg. 2011;254:423–427.CrossRefPubMed Neal MD, Alverdy JC, Hall DE, et al. Diverting loop ileostomy and colonic lavage: an alternative to total abdominal colectomy for the treatment of severe complicated Clostridium difficile associated disease. Ann Surg. 2011;254:423–427.CrossRefPubMed
4.
go back to reference Zainah H, Hassan M, Sheikh-Sroujieh L, et al. Intestinal microbiota transplantation, a simple and effective treatment for severe and refractory Clostridium difficile infection. Dig Dis Sci. 2015;60:181–185.CrossRefPubMed Zainah H, Hassan M, Sheikh-Sroujieh L, et al. Intestinal microbiota transplantation, a simple and effective treatment for severe and refractory Clostridium difficile infection. Dig Dis Sci. 2015;60:181–185.CrossRefPubMed
5.
go back to reference van Nood E, Vrieze A, Nieuwdorp M, et al. Duodenal infusion of donor feces for recurrent Clostridium difficile. NEJM. 2013;368:407–415.CrossRefPubMed van Nood E, Vrieze A, Nieuwdorp M, et al. Duodenal infusion of donor feces for recurrent Clostridium difficile. NEJM. 2013;368:407–415.CrossRefPubMed
6.
go back to reference Quera R, Espinoza R, Estay C, et al. Bacteremia as an adverse event of fecal microbiota transplantation in a patient with Crohn’s disease and recurrent Clostridium difficile infection. J Crohn’s Colitis. 2014;8:252–253.CrossRef Quera R, Espinoza R, Estay C, et al. Bacteremia as an adverse event of fecal microbiota transplantation in a patient with Crohn’s disease and recurrent Clostridium difficile infection. J Crohn’s Colitis. 2014;8:252–253.CrossRef
7.
go back to reference Kelly CR, Ihunnah C, Monika Fischer, et al. Fecal microbiota transplant for treatment of Clostridium difficile infection in immunocompromised patients. Am J Gastroenterol. 2014;109:1065–1071.CrossRefPubMed Kelly CR, Ihunnah C, Monika Fischer, et al. Fecal microbiota transplant for treatment of Clostridium difficile infection in immunocompromised patients. Am J Gastroenterol. 2014;109:1065–1071.CrossRefPubMed
Metadata
Title
Self-Limited Sepsis Syndrome Following Fecal Microbiota Therapy for Refractory C. difficile Infection
Authors
Sundeep Singh
Emily Jing
Neil Stollman
Publication date
01-09-2016
Publisher
Springer US
Published in
Digestive Diseases and Sciences / Issue 9/2016
Print ISSN: 0163-2116
Electronic ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-015-3955-7

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