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Digestive Diseases and Sciences
Published in: Digestive Diseases and Sciences 2/2016

01-02-2016 | Editorial

Risk Factors for Rebleeding in Peptic Ulcer Bleeding: A Second Look at Second-Look Endoscopy

Author: Stig Borbjerg Laursen

Published in: Digestive Diseases and Sciences | Issue 2/2016

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Excerpt

Rebleeding, which occurs in 10–15 % of patients with peptic ulcer bleeding (PUB) [1], is associated with a two- to fivefold mortality increase, depending on the presence of other risk factors [2]. Therefore, identification of the predictors of rebleeding seems meaningful in order to identify high-risk patients needing close observation and rapid treatment in case of the development of rebleeding. …
Literature
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Rosenstock SJ, Møller MH, Larsson H, et al. Improving quality of care in peptic ulcer bleeding: nationwide cohort study of 13,498 consecutive patients in the Danish Clinical Register of Emergency Surgery. Am J Gastroenterol. 2013;108:1449–1457.CrossRefPubMed
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García-Iglesias P, Villoria A, Suarez D, et al. Meta-analysis: predictors of rebleeding after endoscopic treatment for bleeding peptic ulcer. Aliment Pharmacol Ther. 2011;34:888–900.CrossRefPubMed
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Elmunzer BJ, Young SD, Inadomi JM, Schoenfeld P, Laine L. Systematic review of the predictors of recurrent hemorrhage after endoscopic hemostatic therapy for bleeding peptic ulcers. Am J Gastroenterol. 2008;103:2625–2632.CrossRefPubMed
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Vergara M, Bennett C, Calvet X, Gisbert JP. Epinephrine injection versus epinephrine injection and a second endoscopic method in high-risk bleeding ulcers. Cochrane Database Syst Rev. 2014;10:CD005584.PubMed
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El Ouali S, Barkun AN, Wyse J, et al. Is routine second-look endoscopy effective after endoscopic hemostasis in acute peptic ulcer bleeding? A meta-analysis. Gastrointest Endosc. 2012;76:283–292.CrossRefPubMed
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Chiu PW, Joeng H, Choi C, et al. The effect of scheduled second endoscopy against intravenous high dose omeprazole infusion as an adjunct to therapeutic endoscopy in prevention of peptic ulcer rebleeding—a prospective randomized study [abstract]. Gastroenterology. 2006;130:A121.
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Imperiale TF, Kong N. Second-look endoscopy for bleeding peptic ulcer disease: a decision-effectiveness and cost-effectiveness analysis. J Clin Gastroenterol. 2012;46:e71–e75.PubMedCentralCrossRefPubMed
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Kim SB, Lee SH, Kim KO, et al. Risk factors associated with rebleeding in patients with high risk peptic ulcer bleeding: focusing on the role of second look endoscopy. Dig Dis Sci (Epub ahead of print). doi:10.​1007/​s10620-015-3846-y.
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Forrest JA, Finlayson ND, Shearman DJ. Endoscopy in gastrointestinal bleeding. Lancet. 1974;2:394–397.CrossRefPubMed
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Vreeburg EM, de Bruijne HW, Snel P, Bartelsman JW, Rauws EA, Tytgat GN. Previous use of non-steroidal anti-inflammatory drugs and anticoagulants: the influence on clinical outcome of bleeding gastroduodenal ulcers. Eur J Gastroenterol Hepatol. 1997;9:41–44.CrossRefPubMed
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Restellini S, Kherad O, Jairath V, Martel M, Barkun AN. Red blood cell transfusion is associated with increased rebleeding in patients with nonvariceal upper gastrointestinal bleeding. Aliment Pharmacol Ther. 2013;37:316–322.CrossRefPubMed
Metadata
Title
Risk Factors for Rebleeding in Peptic Ulcer Bleeding: A Second Look at Second-Look Endoscopy
Author
Stig Borbjerg Laursen
Publication date
01-02-2016
Publisher
Springer US
Published in
Digestive Diseases and Sciences / Issue 2/2016
Print ISSN: 0163-2116
Electronic ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-015-3919-y

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