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Digestive Diseases and Sciences
Published in: Digestive Diseases and Sciences 10/2015

01-10-2015 | Editorial

Variables Related to Iron Status and Genetic Background Among Korean Populations: Ironing Out the Differences

Author: Paulo Caleb Junior Lima Santos

Published in: Digestive Diseases and Sciences | Issue 10/2015

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Excerpt

Laboratory evidence of elevated iron stores can be an important predictor of cardiovascular diseases, diabetes, neurodegenerative diseases, and cancers [1‐3]. Iron status is routinely evaluated by biochemical assays such as serum iron (SI), total iron-binding capacity (TIBC), and serum ferritin (SF). Although SF has high sensitivity for iron overload, it has low specificity, since inflammatory processes, liver diseases, and alcohol consumption can elevate SF. Transferrin saturation (TS), which is calculated by dividing SI by TIBC, identifies iron overload as well, with TS ≥ 50 % for females or ≥60 % for males suggestive of genetic disease [4]. …
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Metadata
Title
Variables Related to Iron Status and Genetic Background Among Korean Populations: Ironing Out the Differences
Author
Paulo Caleb Junior Lima Santos
Publication date
01-10-2015
Publisher
Springer US
Published in
Digestive Diseases and Sciences / Issue 10/2015
Print ISSN: 0163-2116
Electronic ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-015-3803-9

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