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At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
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Digestive Diseases and Sciences
Literature
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Lucas ML. Diarrhoeal disease through enterocyte secretion: a doctrine untroubled by proof. Exp Physiol. 2010;95:479–484.PubMedCrossRef
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Lucas ML, Thom MMM, Bradley JM, O’Reilly NF, McIlvenny TJ, Nelson YB. Escherichia coli heat stable (STa) enterotoxin and the upper small intestine: lack of evidence in vivo for net fluid secretion. J Mem Biol. 2005;206:29–42.CrossRef
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Lucas ML. Amendments to the theory underlying Ussing chamber data of chloride ion secretion after bacterial enterotoxin exposure. J Theor Biol. 2005;234:21–37.PubMedCrossRef
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Lucas ML, Duncan NW, O’Reilly NF, McIlvenny TJ, Nelson YB. Lack of remote vagally-mediated restoration of Escherichia coli enterotoxin (STa) inhibited fluid absorption from rat proximal jejunum. Neurogastroenterol Motil. 2008;20:532–538.PubMedCrossRef
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Eklund S, Jodal M, Lundgren O. The net fluid secretion caused by cyclic 3‘5‘-guanosine monophosphate in the rat jejunum in vivo is mediated by a local nervous reflex. Acta Physiol Scand. 1986;128:57–63.PubMedCrossRef
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Lucas ML, Tainsh PJ, McColl S, Kenward HL, Watson PC, Gilligan LC, Graham V, Nelson YB. The interaction of stretch, intraluminal pressure and E.coli heat stable (STa) enterotoxin on jejunal fluid absorption in the anaesthetised rat. Proc Physiol Soc. 2008;11:C87.
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Metadata
Title
A Comment on “Enteroendocrine and Neuronal Mechanisms in Pathophysiology of Acute Infectious Diarrhea” by Camilleri, Nullens and Nelsen
Author
Michael L. Lucas
Publication date
01-06-2012
Publisher
Springer US
Published in
Digestive Diseases and Sciences / Issue 6/2012
Print ISSN: 0163-2116
Electronic ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-012-2174-8

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At a glance: The STEP trials

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A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

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