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Published in: Digestive Diseases and Sciences 6/2012

01-06-2012 | Original Article

Hepatic Height on Coronal Computed Tomography Images Predicts Total Liver Volume in European Adults Without Liver Disease

Authors: Philippe Soyer, Marc Sirol, Anthony Dohan, Etienne Gayat, Vinciane Placé, Lora Hristova, Lounis Hamzi, Mourad Boudiaf

Published in: Digestive Diseases and Sciences | Issue 6/2012

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Abstract

Background

Hepatic volume measurement provides useful information in a large range of clinical situations.

Aims

The goal of this study was to test the hypothesis that significant correlation exists between hepatic volume calculated using three-dimensional reconstruction of computed tomography (CT) data and hepatic height calculated using coronal reformation of CT images in European adult patients without liver disease.

Methods

One hundred patients (50 men, 50 women; mean age, 47 years) without hepatic disease were included. Coronal and three-dimensional images of the liver were obtained using 64-section helical CT. Correlation between hepatic height and hepatic volume was searched for using the Pearson correlation test. Regression analysis was used to compare hepatic height and hepatic volume.

Results

A strong and highly significant positive correlation was found between hepatic height and hepatic volume, with a correlation coefficient (r) of 0.767 (95%CI 0.672–0.837; r 2 = 0.588) (P < 0.001). The equation of the correlation line was y = 11.764x − 244 where y represents the hepatic volume in cm3 and x the hepatic height in mm.

Conclusion

Hepatic height as obtained on coronal CT image is a simple and rapid measurement that allows predicting hepatic volume in European adult patients without liver disease.
Literature
1.
go back to reference Calhoun PS, Kuszyk BS, Heath DG, Carley JC, Fishman EK. Three-dimensional volume rendering of spiral CT data: theory and method. Radiographics. 1999;19:745–764.PubMed Calhoun PS, Kuszyk BS, Heath DG, Carley JC, Fishman EK. Three-dimensional volume rendering of spiral CT data: theory and method. Radiographics. 1999;19:745–764.PubMed
2.
go back to reference Hiroshige S, Shimada M, Harada N, et al. Accurate preoperative estimation of liver-graft volumetry using three-dimensional computed tomography. Transplantation. 2003;75:1561–1564.PubMedCrossRef Hiroshige S, Shimada M, Harada N, et al. Accurate preoperative estimation of liver-graft volumetry using three-dimensional computed tomography. Transplantation. 2003;75:1561–1564.PubMedCrossRef
3.
go back to reference Radtke A, Sotiropoulos GC, Nadalin S, et al. Preoperative volume prediction in adult live donor liver transplantation: 3-D CT volumetry approach to prevent miscalculations. Eur J Med Res. 2008;13:319–326.PubMed Radtke A, Sotiropoulos GC, Nadalin S, et al. Preoperative volume prediction in adult live donor liver transplantation: 3-D CT volumetry approach to prevent miscalculations. Eur J Med Res. 2008;13:319–326.PubMed
4.
go back to reference Emiroglu R, Coskun M, Yilmaz U, Sevmis S, Ozcay F, Haberal M. Safety of multidetector computed tomography in calculating liver volume for living-donor liver transplantation. Transpl Proc. 2006;38:3576–3578.CrossRef Emiroglu R, Coskun M, Yilmaz U, Sevmis S, Ozcay F, Haberal M. Safety of multidetector computed tomography in calculating liver volume for living-donor liver transplantation. Transpl Proc. 2006;38:3576–3578.CrossRef
5.
go back to reference Soyer P, Roche A, Elias D, Levesque M. Hepatic metastases from colorectal cancer: influence of hepatic volumetric analysis on surgical decision making. Radiology. 1992;184:695–697.PubMed Soyer P, Roche A, Elias D, Levesque M. Hepatic metastases from colorectal cancer: influence of hepatic volumetric analysis on surgical decision making. Radiology. 1992;184:695–697.PubMed
6.
go back to reference Honda H, Onitsuka H, Masuda K, Nishitani H, Nakata H, Watanabe K. Chronic liver disease: value of volumetry of liver and spleen with computed tomography. Radiat Med. 1990;8:222–226.PubMed Honda H, Onitsuka H, Masuda K, Nishitani H, Nakata H, Watanabe K. Chronic liver disease: value of volumetry of liver and spleen with computed tomography. Radiat Med. 1990;8:222–226.PubMed
7.
go back to reference Sajjad S, Garcia M, Malik A, Van Thiel DH. An assessment of the accuracy of hepatic and splenic size based upon a clinician’s physical examination, a radiologist’s impression and the actual liver and spleen volumes calculated by CT scanning. Dig Dis Sci. 2008;53:1946–1950.PubMedCrossRef Sajjad S, Garcia M, Malik A, Van Thiel DH. An assessment of the accuracy of hepatic and splenic size based upon a clinician’s physical examination, a radiologist’s impression and the actual liver and spleen volumes calculated by CT scanning. Dig Dis Sci. 2008;53:1946–1950.PubMedCrossRef
8.
go back to reference Itai Y, Sekiyama K, Ahmadi T, Obuchi M, Yoshiba M. Fulminant hepatic failure: observation with serial CT. Radiology. 1997;202:379–382.PubMed Itai Y, Sekiyama K, Ahmadi T, Obuchi M, Yoshiba M. Fulminant hepatic failure: observation with serial CT. Radiology. 1997;202:379–382.PubMed
9.
go back to reference Heymsfield SB, Fulenwider T, Nordlinger B, Barlow R, Sones P, Kutner MH. Accurate measurement of liver, kidney, and spleen volume and mass by computerized axial tomography. Ann Intern Med. 1979;90:185–187.PubMed Heymsfield SB, Fulenwider T, Nordlinger B, Barlow R, Sones P, Kutner MH. Accurate measurement of liver, kidney, and spleen volume and mass by computerized axial tomography. Ann Intern Med. 1979;90:185–187.PubMed
10.
go back to reference Nawaratne S, Fabiny R, Brien JE, et al. Accuracy of volume measurement using helical CT. J Comput Assist Tomogr. 1997;21:481–486.PubMedCrossRef Nawaratne S, Fabiny R, Brien JE, et al. Accuracy of volume measurement using helical CT. J Comput Assist Tomogr. 1997;21:481–486.PubMedCrossRef
11.
go back to reference Luccichenti G, Cademartiri F, Cobelli R, Pavone P. Assessment of organ volume with different techniques using a living liver model. Eur Radiol. 2003;13:1286–1290.PubMed Luccichenti G, Cademartiri F, Cobelli R, Pavone P. Assessment of organ volume with different techniques using a living liver model. Eur Radiol. 2003;13:1286–1290.PubMed
12.
go back to reference Castell DO, O’Brien KD, Muench H, Chalmers TC. Estimation of liver size by percussion in normal individuals. Ann Intern Med. 1969;70:1183–1189.PubMed Castell DO, O’Brien KD, Muench H, Chalmers TC. Estimation of liver size by percussion in normal individuals. Ann Intern Med. 1969;70:1183–1189.PubMed
13.
go back to reference Zoli M, Magalotti D, Grimaldi M, Gueli C, Marchesini G, Pisi E. Physical examination of the liver: is it still worth it? Am J Gastroenterol. 1995;90:1428–1432.PubMed Zoli M, Magalotti D, Grimaldi M, Gueli C, Marchesini G, Pisi E. Physical examination of the liver: is it still worth it? Am J Gastroenterol. 1995;90:1428–1432.PubMed
14.
15.
go back to reference Urata K, Kawasaki S, Matsunami H, et al. Calculation of child and adult standard liver volume for liver transplantation. Hepatology. 1995;21:1317–1321.PubMedCrossRef Urata K, Kawasaki S, Matsunami H, et al. Calculation of child and adult standard liver volume for liver transplantation. Hepatology. 1995;21:1317–1321.PubMedCrossRef
16.
go back to reference Kayashima H, Taketomi A, Yonemura Y, et al. Accuracy of an age-adjusted formula in assessing the graft volume in living donor liver transplantation. Liver Transpl. 2008;14:1366–1371.PubMedCrossRef Kayashima H, Taketomi A, Yonemura Y, et al. Accuracy of an age-adjusted formula in assessing the graft volume in living donor liver transplantation. Liver Transpl. 2008;14:1366–1371.PubMedCrossRef
17.
go back to reference Walter J, Orth SI, Broering DC. The accuracy of estimations of liver volume. Liver Transpl. 2010;16:786–787.PubMed Walter J, Orth SI, Broering DC. The accuracy of estimations of liver volume. Liver Transpl. 2010;16:786–787.PubMed
18.
go back to reference Vauthey JN, Abdalla EK, Doherty DA, et al. Body surface area and body weight predict total liver volume in Western adults. Liver Transpl. 2002;8:233–240.PubMedCrossRef Vauthey JN, Abdalla EK, Doherty DA, et al. Body surface area and body weight predict total liver volume in Western adults. Liver Transpl. 2002;8:233–240.PubMedCrossRef
19.
go back to reference Heinemann A, Wischhusen F, Püschel K, Rogiers X. Standard liver volume in the Caucasian population. Liver Transpl Surg. 1999;5:366–368.PubMedCrossRef Heinemann A, Wischhusen F, Püschel K, Rogiers X. Standard liver volume in the Caucasian population. Liver Transpl Surg. 1999;5:366–368.PubMedCrossRef
20.
go back to reference Yoshizumi T, Taketomi A, Kayashima H, et al. Estimation of standard liver volume for Japanese adults. Transpl Proc. 2008;40:1456–1460.CrossRef Yoshizumi T, Taketomi A, Kayashima H, et al. Estimation of standard liver volume for Japanese adults. Transpl Proc. 2008;40:1456–1460.CrossRef
21.
go back to reference Groell R, Machan L, Schaffler GJ, Uggowitzer M, Peichel KH. Morphometric measurement of abdominal organs: comparison of ultrasound and spiral CT. Acta Radiol. 1997;38:982–985.PubMed Groell R, Machan L, Schaffler GJ, Uggowitzer M, Peichel KH. Morphometric measurement of abdominal organs: comparison of ultrasound and spiral CT. Acta Radiol. 1997;38:982–985.PubMed
22.
go back to reference Rosenfield AT, Schneider PB. Rapid evaluation of hepatic size on radioisotope scan. J Nucl Med. 1974;15:237–240.PubMed Rosenfield AT, Schneider PB. Rapid evaluation of hepatic size on radioisotope scan. J Nucl Med. 1974;15:237–240.PubMed
23.
go back to reference Radin DR, Coletti PM, Ralls PW, Boswell WD, Halls JM. Agenesis of the right lobe of the liver. Radiology. 1987;164:639–642.PubMed Radin DR, Coletti PM, Ralls PW, Boswell WD, Halls JM. Agenesis of the right lobe of the liver. Radiology. 1987;164:639–642.PubMed
24.
go back to reference Verma SK, McClure K, Parker L, Mitchell DG, Verma M, Bergin D. Simple linear measurements of the normal liver: interobserver agreement and correlation with hepatic volume on MRI. Clin Radiol. 2010;65:315–318.PubMedCrossRef Verma SK, McClure K, Parker L, Mitchell DG, Verma M, Bergin D. Simple linear measurements of the normal liver: interobserver agreement and correlation with hepatic volume on MRI. Clin Radiol. 2010;65:315–318.PubMedCrossRef
25.
go back to reference Boscaini M, Pietri H. Determination of a hepatic volumetric index by ultrasonic scanning. Surg Endosc. 1987;1:103–107.PubMedCrossRef Boscaini M, Pietri H. Determination of a hepatic volumetric index by ultrasonic scanning. Surg Endosc. 1987;1:103–107.PubMedCrossRef
26.
go back to reference Geraghty EM, Boone JM, McGahan JP, Jain K. Normal organ volume assessment from abdominal CT. Abdom Imaging. 2004;29:482–490.PubMedCrossRef Geraghty EM, Boone JM, McGahan JP, Jain K. Normal organ volume assessment from abdominal CT. Abdom Imaging. 2004;29:482–490.PubMedCrossRef
27.
go back to reference Henderson JM, Heymsfield SB, Horowitz J, Kutner MH. Measurement of liver and spleen volume by computed tomography: assessment of reproducibility and changes found following a selective distal splenorenal shunt. Radiology. 1981;141:525–527.PubMed Henderson JM, Heymsfield SB, Horowitz J, Kutner MH. Measurement of liver and spleen volume by computed tomography: assessment of reproducibility and changes found following a selective distal splenorenal shunt. Radiology. 1981;141:525–527.PubMed
28.
go back to reference Sandrasegaran K, Kwo PW, DiGirolamo D, Stockberger SM Jr, Cummings OW, Kopecky KK. Measurement of liver volume using spiral CT and the curved line and cubic spline algorithms: reproducibility and interobserver variation. Abdom Imaging. 1999;24:61–65.PubMedCrossRef Sandrasegaran K, Kwo PW, DiGirolamo D, Stockberger SM Jr, Cummings OW, Kopecky KK. Measurement of liver volume using spiral CT and the curved line and cubic spline algorithms: reproducibility and interobserver variation. Abdom Imaging. 1999;24:61–65.PubMedCrossRef
29.
go back to reference Gao L, Heath DG, Kuszyk BS, Fishman EK. Automatic liver segmentation technique for three-dimensional visualization of CT data. Radiology. 1996;201:359–364.PubMed Gao L, Heath DG, Kuszyk BS, Fishman EK. Automatic liver segmentation technique for three-dimensional visualization of CT data. Radiology. 1996;201:359–364.PubMed
30.
go back to reference Farjo LA, Williams DM, Bland PH, Francis IR, Meyer CR. Determination of liver volume from CT scans using histogram cluster analysis. J Comput Assist Tomogr. 1992;16:674–683.PubMedCrossRef Farjo LA, Williams DM, Bland PH, Francis IR, Meyer CR. Determination of liver volume from CT scans using histogram cluster analysis. J Comput Assist Tomogr. 1992;16:674–683.PubMedCrossRef
31.
go back to reference Chandramohan A, Eapen A, Govil S, Govil S, Jeyaseelan V. Determining standard liver volume: assessment of existing formulae in Indian population. Indian J Gastroenterol. 2007;26:22–25.PubMed Chandramohan A, Eapen A, Govil S, Govil S, Jeyaseelan V. Determining standard liver volume: assessment of existing formulae in Indian population. Indian J Gastroenterol. 2007;26:22–25.PubMed
Metadata
Title
Hepatic Height on Coronal Computed Tomography Images Predicts Total Liver Volume in European Adults Without Liver Disease
Authors
Philippe Soyer
Marc Sirol
Anthony Dohan
Etienne Gayat
Vinciane Placé
Lora Hristova
Lounis Hamzi
Mourad Boudiaf
Publication date
01-06-2012
Publisher
Springer US
Published in
Digestive Diseases and Sciences / Issue 6/2012
Print ISSN: 0163-2116
Electronic ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-012-2077-8

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