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Digestive Diseases and Sciences
Published in: Digestive Diseases and Sciences 1/2011

01-01-2011 | Original Article

Small Intestinal Clustered Contractions and Bacterial Overgrowth: A Frequent Finding in Obese Patients

Authors: Ana María Madrid, Jaime Poniachik, Rodrigo Quera, Carlos Defilippi

Published in: Digestive Diseases and Sciences | Issue 1/2011

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Abstract

Background

Small intestinal bacterial overgrowth (SIBO) has been observed in several disorders of the gastrointestinal tract. Studies have shown abnormalities of motor function in obese patients, and there is indirect evidence suggesting that SIBO is present in them.

Aims

To study small intestinal motility and the prevalence of SIBO in obese patients and to determine whether there was any relationship between both parameters.

Methods

Thirty-nine patients scheduled for bariatric surgery were subjected to hydrogen breath test with lactulose and to a stationary small intestinal motility study with perfused catheters.

Results

SIBO was observed in 41% of obese patients and was not related to body mass index. Small intestinal manometry showed a marked increase of clustered contractions in obese patients with SIBO compared to obese subjects without SIBO, whereas all the other parameters of fasting cyclic activity were not different.

Conclusions

SIBO was a frequent finding in obese patients and was associated with an increased pattern of clustered contractions, which was not observed in absence of SIBO.
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Metadata
Title
Small Intestinal Clustered Contractions and Bacterial Overgrowth: A Frequent Finding in Obese Patients
Authors
Ana María Madrid
Jaime Poniachik
Rodrigo Quera
Carlos Defilippi
Publication date
01-01-2011
Publisher
Springer US
Published in
Digestive Diseases and Sciences / Issue 1/2011
Print ISSN: 0163-2116
Electronic ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-010-1239-9

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