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Published in: Digestive Diseases and Sciences 6/2007

01-06-2007 | Original Article

Endoscopic Resection of a Duodenal Gangliocytic Paraganglioma

Authors: Tomoko Morita, Satoru Tamura, Yuichi Yokoyama, Tomoko Onishi, Yoshinori Kuratani, Hiroshi Mizuta, Saburo Onishi

Published in: Digestive Diseases and Sciences | Issue 6/2007

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Abstract

A gangliocytic paraganglioma (GP) is an extremely rare neurogenic tumor nearly located in the second portion of the duodenum and has been regarded as benign. We report a case of duodenal GP in a 53-year-old man. The GP arose in the second portion of the duodenum and was shown by histological examination to consist of epithelioid cells, spindle cells, and ganglion-like cells. An endoscopic ultrasonography showed a round, well-demarcated, inhomogeneous, submucosal tumor in the 3rd-4th layer. We resected it by endoscopic mucosal resection.
Literature
1.
go back to reference Perrone T, Sibley RK, Rosai J (1985) Duodenal gangliocytic paraganglioma. An immunohistochemical and ultrastructural study and a hypothesis concerning its origin. Am J Pathol 9:31–41CrossRef Perrone T, Sibley RK, Rosai J (1985) Duodenal gangliocytic paraganglioma. An immunohistochemical and ultrastructural study and a hypothesis concerning its origin. Am J Pathol 9:31–41CrossRef
2.
go back to reference Scheithauer BW, Nora FE, Lechago J, Wick MP, Crawford BG, Weiland LH, Carney JA (1986) Duodenal gangliocytic paraganglioma. Clinicopathologicand immunohistorogical study of 11cases. Am J Clin Pathol 86:559–565PubMed Scheithauer BW, Nora FE, Lechago J, Wick MP, Crawford BG, Weiland LH, Carney JA (1986) Duodenal gangliocytic paraganglioma. Clinicopathologicand immunohistorogical study of 11cases. Am J Clin Pathol 86:559–565PubMed
3.
go back to reference Stephens M, Williams GT, Jasani B, Williams ED (1987) Synchronous duodenal neuroendocrine tumors in von Recklinghausen's disease—a case report of co-existing gangliocytic paraganglioma and somatostatin-rich glandular cartinoid. Histology 11:1331–1340 Stephens M, Williams GT, Jasani B, Williams ED (1987) Synchronous duodenal neuroendocrine tumors in von Recklinghausen's disease—a case report of co-existing gangliocytic paraganglioma and somatostatin-rich glandular cartinoid. Histology 11:1331–1340
4.
go back to reference Dahl EV, Waugh JM, Dajin DC (1957) Gastrointestinal ganglioneuroma. Brief review with report of a duodenal ganglioneuroma. Am J Pathol 33:953–965PubMed Dahl EV, Waugh JM, Dajin DC (1957) Gastrointestinal ganglioneuroma. Brief review with report of a duodenal ganglioneuroma. Am J Pathol 33:953–965PubMed
5.
go back to reference Nakamura T, Ozawa T, Takehira Y, Kitagawa M, Yamada M, Yasumi K, Tamakoshi K, Kobayashi Y, Nakamura H (2002) Endoscopic resection of gangliocytic paraganglioma of the minor duodenal papilla: case report and review. Gastrointest Endosc 55:270–273PubMedCrossRef Nakamura T, Ozawa T, Takehira Y, Kitagawa M, Yamada M, Yasumi K, Tamakoshi K, Kobayashi Y, Nakamura H (2002) Endoscopic resection of gangliocytic paraganglioma of the minor duodenal papilla: case report and review. Gastrointest Endosc 55:270–273PubMedCrossRef
6.
go back to reference Burke A, Helwig E (1988) Gangliocytic paraganglioma of the small intestine. Lab Invest 58:13A (abstr) Burke A, Helwig E (1988) Gangliocytic paraganglioma of the small intestine. Lab Invest 58:13A (abstr)
7.
8.
go back to reference Scheithauer BW, Nora FE, LeChago J, Wick MR, Crawford BG, Weiland LH, Carney JA (1986) Duodenal gangliocytic paraganglioma:clinicopathologic and immunohistochemical study of 11 cases. Am J Clin Pathol 86:559–565PubMed Scheithauer BW, Nora FE, LeChago J, Wick MR, Crawford BG, Weiland LH, Carney JA (1986) Duodenal gangliocytic paraganglioma:clinicopathologic and immunohistochemical study of 11 cases. Am J Clin Pathol 86:559–565PubMed
9.
go back to reference Smithline AE, Hawes RH, Kopecky KK, Cummings OW, Kumar S (1993) Gangliocytic paraganglioma, a rare cause of upper gastrointestinal bleeding, endoscopic ultrasound findings presented. Dig Dis Sci 38:173–177PubMedCrossRef Smithline AE, Hawes RH, Kopecky KK, Cummings OW, Kumar S (1993) Gangliocytic paraganglioma, a rare cause of upper gastrointestinal bleeding, endoscopic ultrasound findings presented. Dig Dis Sci 38:173–177PubMedCrossRef
10.
go back to reference Coony T, Sweeney EC (1979) Paraganglioneuroma of duodenum: An evolutionary hybrid? J ClinPathol 31:233–244 Coony T, Sweeney EC (1979) Paraganglioneuroma of duodenum: An evolutionary hybrid? J ClinPathol 31:233–244
11.
go back to reference Qizilbash AH (1973) Benign paraganglioma of duodenum. Arch Pathol 96:276–280PubMed Qizilbash AH (1973) Benign paraganglioma of duodenum. Arch Pathol 96:276–280PubMed
12.
go back to reference Taylor HB, Helwig EB (1962) Benign nonchromaffin paragangliomas of duodenum. Virchows Arch [Pathol Anat] 335:356–366CrossRef Taylor HB, Helwig EB (1962) Benign nonchromaffin paragangliomas of duodenum. Virchows Arch [Pathol Anat] 335:356–366CrossRef
13.
go back to reference Kepes JJ, Zacharias DL (1971) Gangliocytic paraganglioma of the duodenum. A report of two cases with light and electron microscopic examination. Cancer 1:207–216 Kepes JJ, Zacharias DL (1971) Gangliocytic paraganglioma of the duodenum. A report of two cases with light and electron microscopic examination. Cancer 1:207–216
14.
go back to reference Schroder HD, Johannsen L (1986) Demonstration of S-100 protein in sustentacular cells of phaeochromocytomas and paragangliomas. Histopathology 10:1023–1033PubMedCrossRef Schroder HD, Johannsen L (1986) Demonstration of S-100 protein in sustentacular cells of phaeochromocytomas and paragangliomas. Histopathology 10:1023–1033PubMedCrossRef
15.
go back to reference Furihata M, Ohtsuki Y (1991) Immunohistochemical characterization of HLA-DR-antigen positive dendric cells in phaeochromocytomas and paragangliomas as a prognostic marker. Virchows Arch Pathol Anat Histopathol 418:33–39CrossRef Furihata M, Ohtsuki Y (1991) Immunohistochemical characterization of HLA-DR-antigen positive dendric cells in phaeochromocytomas and paragangliomas as a prognostic marker. Virchows Arch Pathol Anat Histopathol 418:33–39CrossRef
16.
go back to reference Barbareschi M, Frigo B, Aldovini D, Leonardi E, Cristina S, Falleni M (1989) Duodenal gangliocystic paraganglioma:r eport of a case and review of the literature. Virchows Arch A Pathol Avat Histopathol 416:81–89CrossRef Barbareschi M, Frigo B, Aldovini D, Leonardi E, Cristina S, Falleni M (1989) Duodenal gangliocystic paraganglioma:r eport of a case and review of the literature. Virchows Arch A Pathol Avat Histopathol 416:81–89CrossRef
17.
go back to reference Bruke AP, Helwig EB (1989) Gangliocytic paraganglioma. Am J Clin Pathol 92:1–9 Bruke AP, Helwig EB (1989) Gangliocytic paraganglioma. Am J Clin Pathol 92:1–9
18.
go back to reference Imai K, Kobuke T, Yonehara S, Tokuoka S (1989) Duodenal gangliocytic paraganglioma with lymph node metastasis in a 17-year-old boy. Cancer 63:2540–2545CrossRef Imai K, Kobuke T, Yonehara S, Tokuoka S (1989) Duodenal gangliocytic paraganglioma with lymph node metastasis in a 17-year-old boy. Cancer 63:2540–2545CrossRef
19.
go back to reference Büchler M, Malfertheiner P, Baczako K, Krantzberger W, Berger HG (1985) A metastatic endocrine-neurogenic tumor of ampulla of Vater with multiple endocrine immunoreaction-malignant paraganglioma? Digestion 31:54–59PubMedCrossRef Büchler M, Malfertheiner P, Baczako K, Krantzberger W, Berger HG (1985) A metastatic endocrine-neurogenic tumor of ampulla of Vater with multiple endocrine immunoreaction-malignant paraganglioma? Digestion 31:54–59PubMedCrossRef
20.
go back to reference Dookhan DB, Miettinen M, Finkel G, Jibas Z (1993) Recurrent duodenal gangliocytic paraganglioma with lymph node metastases. Histopathology 22:399–401PubMedCrossRef Dookhan DB, Miettinen M, Finkel G, Jibas Z (1993) Recurrent duodenal gangliocytic paraganglioma with lymph node metastases. Histopathology 22:399–401PubMedCrossRef
21.
go back to reference Hashimoto S, Kawasaki S, Matsuzawa K, Harada H, Makuuchi M (1992) Gangliocytic paraganglioma of the papilla of Vater with regional lymph node metastasis. Am J Gastroenterol 87:1216–1218PubMed Hashimoto S, Kawasaki S, Matsuzawa K, Harada H, Makuuchi M (1992) Gangliocytic paraganglioma of the papilla of Vater with regional lymph node metastasis. Am J Gastroenterol 87:1216–1218PubMed
Metadata
Title
Endoscopic Resection of a Duodenal Gangliocytic Paraganglioma
Authors
Tomoko Morita
Satoru Tamura
Yuichi Yokoyama
Tomoko Onishi
Yoshinori Kuratani
Hiroshi Mizuta
Saburo Onishi
Publication date
01-06-2007
Published in
Digestive Diseases and Sciences / Issue 6/2007
Print ISSN: 0163-2116
Electronic ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-006-9370-3

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