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Digestive Diseases and Sciences
Published in: Digestive Diseases and Sciences 10/2007

01-10-2007 | Original Paper

Impact of Nocturnal Heartburn on Quality of Life, Sleep, and Productivity: The SINERGE Study

Authors: José Luis Calleja, M. Bixquert, J. Maldonado, for the SINERGE Study Group

Published in: Digestive Diseases and Sciences | Issue 10/2007

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Abstract

The aim of the SINERGE study was to assess the impact of nocturnal heartburn on quality of life, sleep, and productivity. Ambulatory patients ≥18 years old and classified as defined cases of nocturnal heartburn (n=337), nonnocturnal heartburn (n=139), uncontrolled hypertension (n=198), and symptomatic depression (n=104) were included in this cross-sectional study. Information on age, gender, body mass index, and comorbidity was collected and the following validated questionnaires were applied: SF-12, Pittsburgh Sleep Quality Index, and Work Productivity and Activity Impairment questionnaire. The prevalence of primary care consultation for heartburn and nocturnal heartburn was 4.7% and 1.9%, respectively. Health-related quality of life, sleep, and productivity were significantly impaired in patients with frequent nocturnal heartburn symptoms as compared with those of the patients without nocturnal symptoms or patients with hypertension. Nocturnal heartburn poses a considerable burden for the sufferer because of the impact on quality of life, sleep, and daily activities.
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Metadata
Title
Impact of Nocturnal Heartburn on Quality of Life, Sleep, and Productivity: The SINERGE Study
Authors
José Luis Calleja
M. Bixquert
J. Maldonado
for the SINERGE Study Group
Publication date
01-10-2007
Publisher
Springer US
Published in
Digestive Diseases and Sciences / Issue 10/2007
Print ISSN: 0163-2116
Electronic ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-006-9196-z

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