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Cardiovascular Drugs and Therapy

Published in:

01-02-2008

Management of Tako-tsubo Syndrome

Authors: Jason M. Tarkin, Maher Khetyar, Juan C. Kaski

Published in: Cardiovascular Drugs and Therapy | Issue 1/2008

Abstract

Introduction

This manuscript reviews the current evidence for proposed pathophysiological mechanisms of Tako-tsubo syndrome and its management.

Discussion

The Tako-tsubo syndrome is defined by the presence of transient left ventricular apical ballooning after an acute coronary syndrome in patients with angiographically normal coronary arteries. Intriguingly, only the apex is affected and compensatory basal hypercontractility is seen. Several mechanisms have been offered as explanations for the characteristic clinical presentation and echocardiographic appearance of this syndrome.

Conclusion

Tako-tsubo syndrome encompasses heterogeneous patient populations and it is likely that different pathogenic mechanisms may operate in different patients. Treatment of the condition is at present empirical and aimed at preserving ventricular function.

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Title: Management of Tako-tsubo Syndrome
Authors: Jason M. Tarkin
Maher Khetyar
Juan C. Kaski
Publication date: 01-02-2008
Publisher: Springer US
Published in: Cardiovascular Drugs and Therapy / Issue 1/2008
Print ISSN: 0920-3206
Electronic ISSN: 1573-7241
DOI: https://doi.org/10.1007/s10557-007-6074-7

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