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Published in: Cancer Causes & Control 2/2018

01-02-2018 | Original paper

Rural–urban differences in surgical treatment, regional lymph node examination, and survival in endometrial cancer patients

Authors: Whitney E. Zahnd, Katherine S. Hyon, Paula Diaz-Sylvester, Sonya R. Izadi, Graham A. Colditz, Laurent Brard

Published in: Cancer Causes & Control | Issue 2/2018

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Abstract

Purpose

Endometrial cancer (EC) is the most common gynecological malignancy and one of few cancers with an increasing US mortality rate. Rural patients may have less access to specialty care affecting their receipt of surgery and adequate lymphadenectomy (AL). We sought to assess rural–urban differences in EC surgery, lymphadenectomy, and survival.

Methods

We analyzed data from the Surveillance Epidemiology and End Results database on EC patients (2004–2013). We performed univariate analyses to compare rural and urban patients on demographic and clinical characteristics and receipt of nodal examination and AL. We assessed rural–urban differences in trends of receipt of AL, performed logistic regression to evaluate differences in receipt of surgery, nodal examination, and AL, and performed survival analysis.

Results

Rural patients were less likely to have any lymph nodes removed, had a smaller median number removed, and a smaller proportion had AL. Even after controlling for established risk factors, rural patients had lower odds of lymph node examination and adequate AL than urban patients and also had poorer survival.

Conclusions

Future research should continue to assess the association between access to care and disparities in surgical care and the effect of these disparities on survival.
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Metadata
Title
Rural–urban differences in surgical treatment, regional lymph node examination, and survival in endometrial cancer patients
Authors
Whitney E. Zahnd
Katherine S. Hyon
Paula Diaz-Sylvester
Sonya R. Izadi
Graham A. Colditz
Laurent Brard
Publication date
01-02-2018
Publisher
Springer International Publishing
Published in
Cancer Causes & Control / Issue 2/2018
Print ISSN: 0957-5243
Electronic ISSN: 1573-7225
DOI
https://doi.org/10.1007/s10552-017-0998-4

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