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Cancer Causes & Control
Published in: Cancer Causes & Control 4/2017

01-04-2017 | Original paper

Physical activity and lung cancer risk in men and women

Authors: Vikki Ho, Marie-Elise Parent, Javier Pintos, Michal Abrahamowicz, Coraline Danieli, Lesley Richardson, Robert Bourbonnais, Lise Gauvin, Jack Siemiatycki, Anita Koushik

Published in: Cancer Causes & Control | Issue 4/2017

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Abstract

Purpose

Although evidence has accumulated that recreational physical activities (PA) may reduce lung cancer risk, there is little evidence concerning the possible role of a potentially more important source of PA, namely occupational PA. We investigated both recreational and lifetime occupational PA in relation to lung cancer risk in a population-based case–control study in Montreal, Canada (NCASES = 727; NCONTROLS = 1,351).

Methods

Unconditional logistic regression was used to estimate odds ratios (OR), separately for men and women, adjusting for smoking, exposure to occupational carcinogens, and sociodemographic and lifestyle factors.

Results

In both sexes, increasing recreational PA was associated with a lower lung cancer risk (ORMEN = 0.66, 95% confidence interval (CI) 0.47–0.92; ORWOMEN = 0.55, 95% CI 0.34–0.88, comparing the highest versus lowest tertiles). For occupational PA, no association was observed among women, while increasing occupational PA was associated with increased risk among men (ORMEN = 1.96, 95% CI 1.27–3.01). ORs were not modified by occupational lung carcinogen exposure, body mass index, and smoking level; results were similar across lung cancer histological types.

Conclusions

Our results support the previous findings for recreational PA and lung cancer risk. Unexpectedly, our findings suggest a positive association for occupational PA; this requires replication and more detailed investigation.
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Metadata
Title
Physical activity and lung cancer risk in men and women
Authors
Vikki Ho
Marie-Elise Parent
Javier Pintos
Michal Abrahamowicz
Coraline Danieli
Lesley Richardson
Robert Bourbonnais
Lise Gauvin
Jack Siemiatycki
Anita Koushik
Publication date
01-04-2017
Publisher
Springer International Publishing
Published in
Cancer Causes & Control / Issue 4/2017
Print ISSN: 0957-5243
Electronic ISSN: 1573-7225
DOI
https://doi.org/10.1007/s10552-017-0872-4

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