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Breast Cancer Research and Treatment

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Open Access 01-02-2020 | Breast Cancer | Preclinical study

Symptom cluster of pain, fatigue, and psychological distress in breast cancer survivors: prevalence and characteristics

Authors: Ellen Bjerkeset, Kari Röhrl, Inger Schou-Bredal

Published in: Breast Cancer Research and Treatment | Issue 1/2020

Abstract

Purpose

Breast cancer survivors may experience pain, fatigue, or psychological distress as a result of the treatment. These symptoms may co-occur and form a cluster. However little is known about symptom clusters (SCs) in long-term breast cancer survivors. This study aimed to identify subgroups of breast cancer survivors with the SC of pain, fatigue, and psychological distress, and to examine sociodemographic and clinical characteristics associated with this SC.

Methods

Data were obtained from a nationwide survey of breast cancer survivors (N = 834). Exhaustive enumeration of possible combination of the three binary variables (pain, fatigue, psychological distress) was conducted. They were identified using the recommended threshold for the Hospital Anxiety and Depression Scale, the Fatigue Questionnaire, and a score of one or more on a numeric rating scale for pain. The SC was defined to include all the three variables, all other combinations were defined as no SC. Logistic regression analyses were conducted to examine the association between sociodemographic and clinical variables and the SC.

Results

Of the 834 survivors, 13% had the SC. Younger age (OR 2.3, 95% CI 1.3–4.1, p = 0.003), lymphedema (OR 1.9, 95% CI 1.1–3.2, p = 0.02), working part-time (OR 2.9, 95% CI 1.6–5.3, p < 0.001), or being disabled (OR 4.1, 95% CI 2.2–7.8, p < 0.001) were all associated with the SC.

Conclusion

Thirteen percent of the survivors experienced the SC. It appears that premenstrual women are at greater risk, than postmenopausal women. Having this SC might have an impact on the survivors’ ability to work.

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Title: Symptom cluster of pain, fatigue, and psychological distress in breast cancer survivors: prevalence and characteristics
Authors: Ellen Bjerkeset
Kari Röhrl
Inger Schou-Bredal
Publication date: 01-02-2020
Publisher: Springer US
Keywords: Breast Cancer
Lymphedema
Breast Cancer
Fatigue
Published in: Breast Cancer Research and Treatment / Issue 1/2020
Print ISSN: 0167-6806
Electronic ISSN: 1573-7217
DOI: https://doi.org/10.1007/s10549-020-05522-8

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