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01-06-2010 | Invited Commentary

Discussion: immediate post-mastectomy breast reconstruction followed by radiotherapy: risk factors for complications

Authors: Amy K. Alderman, Reshma Jagsi

Published in: Breast Cancer Research and Treatment | Issue 3/2010

Excerpt

Dr. Cowen and co-authors should be commended for their efforts to describe patterns and correlates of complications after mastectomy with immediate tissue expander/implant reconstruction and adjuvant post-mastectomy radiotherapy. It is important for clinicians to understand the outcomes and predictors of successful breast reconstruction among patients receiving radiotherapy. Post-mastectomy radiation therapy is now considered to be an integral component of cancer treatment for many patients. Radiation therapy is associated with a two-thirds reduction in the relative risk of loco-regional failure and a survival benefit in appropriately selected patients [1]. However, radiation is not without its risks. Several retrospective studies have suggested that radiation increases the risk of post-operative complications in patients with expander/implant reconstructions [2]. Therefore, understanding the risk factors for post-operative complications in the setting of reconstruction and radiation will help to improve the informed consent process and assist clinicians and patients alike with treatment decision-making. …

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Title: Discussion: immediate post-mastectomy breast reconstruction followed by radiotherapy: risk factors for complications
Authors: Amy K. Alderman
Reshma Jagsi
Publication date: 01-06-2010
Publisher: Springer US
Published in: Breast Cancer Research and Treatment / Issue 3/2010
Print ISSN: 0167-6806
Electronic ISSN: 1573-7217
DOI: https://doi.org/10.1007/s10549-010-0878-z

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