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Published in: Administration and Policy in Mental Health and Mental Health Services Research 6/2009

01-11-2009 | Original Paper

Antidepressant Adherence After Psychiatric Hospitalization Among VA Patients with Depression

Authors: Kara Zivin, Dara Ganoczy, Paul N. Pfeiffer, Erin M. Miller, Marcia Valenstein

Published in: Administration and Policy in Mental Health and Mental Health Services Research | Issue 6/2009

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Abstract

Depressed patients discharged from psychiatric hospitalizations face increased risks for adverse outcomes including suicide, yet antidepressant adherence rates during this high-risk period are unknown. Using Veterans Affairs (VA) data, we assessed antidepressant adherence and predictors of poor adherence among depressed veterans following psychiatric hospitalization. We identified VA patients nationwide with depressive disorders who had a psychiatric hospitalization between April 1, 1999 and September 30, 2003, received antidepressant medication, and had an outpatient appointment following discharge. We calculated medication possession ratios (MPRs), a measure of medication adherence, within 3 and 6 months following discharge. We assessed patient factors associated with having lower levels of adherence (MPRs < 0.8) after discharge. The criteria for 3- and 6-month MPRs were met by 20,931 and 23,182 patients respectively. The mean 3 month MPR was 0.79 (SD = 0.37). The mean 6 month MPR was 0.66 (SD = 0.40). Patients with poorer adherence were male, younger, non-white, and had a substance abuse disorder, but were less likely to have PTSD or other anxiety disorders. Poor antidepressant adherence is common among depressed patients after psychiatric hospitalization. Efforts to improve adherence at this time may be critical in improving the outcomes of these high-risk patients.
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Metadata
Title
Antidepressant Adherence After Psychiatric Hospitalization Among VA Patients with Depression
Authors
Kara Zivin
Dara Ganoczy
Paul N. Pfeiffer
Erin M. Miller
Marcia Valenstein
Publication date
01-11-2009
Publisher
Springer US
Published in
Administration and Policy in Mental Health and Mental Health Services Research / Issue 6/2009
Print ISSN: 0894-587X
Electronic ISSN: 1573-3289
DOI
https://doi.org/10.1007/s10488-009-0230-2

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