Top

Published in:

01-05-2018 | Original Paper

A Cross-Sectional Study of Depressive Symptoms and Risky Alcohol Use Behaviors Among HIV Primary Care Patients in New York City

Authors: Yasemin Algur, Jennifer C. Elliott, Efrat Aharonovich, Deborah S. Hasin

Published in: AIDS and Behavior | Issue 5/2018

Abstract

An association between problem drinking and depression among HIV-infected individuals has been previously demonstrated; however, which specific risky drinking behaviors are associated with higher levels of depression has not yet been investigated. Using an adult sample of HIV-infected primary care patients (78% male, 94% Black or Hispanic), we investigated whether depressive symptoms are associated with various risky drinking behaviors. Participants were administered the Beck Depression Inventory-II to assess depressive symptoms, and the Alcohol Use Disorders and Associated Disabilities Interview Schedule-IV to evaluate alcohol involvement. Participants with depressive symptoms (26%) were at higher risk for alcohol dependence [adjusted odds ratio (AOR) 3.8; 95% CI 2.0–7.2], regular binge drinking (AOR 2.0; 95% CI 1.1–3.8), and regular daytime drinking (AOR 2.1; 95% CI 1.2–3.8), in comparison with their non-depressed counterparts. Because both depression and unhealthy drinking negatively affect medication adherence and clinical outcomes, a better understanding of the association between depression and certain risky drinking behaviors among HIV-infected individuals is vital to improving their care and prognoses.

Petry NM. Alcohol use in HIV patients: what we don’t know may hurt us. Int J STD AIDS. 1999;10(9):561–70.CrossRefPubMed

Dew MA, Becker JT, Sanchez J, et al. Prevalence and predictors of depressive, anxiety and substance use disorders in HIV-infected and uninfected men: a longitudinal evaluation. Psychol Med. 1997;27(2):395–409.CrossRefPubMed

Cook RL, Sereika SM, Hunt SC, Woodward WC, Erlen JA, Conigliaro J. Problem drinking and medication adherence among persons with HIV infection. J Gen Intern Med. 2001;16(2):83–8.CrossRefPubMedPubMedCentral

Williams JB, Rabkin JG, Remien RH, Gorman JM, Ehrhardt AA. Multidisciplinary baseline assessment of homosexual men with and without human immunodeficiency virus infection. II. Standardized clinical assessment of current and lifetime psychopathology. Arch Gen Psychiatry. 1991;48(2):124–30.CrossRefPubMed

Samet JH, Phillips SJ, Horton NJ, Traphagen ET, Freedberg KA. Detecting alcohol problems in HIV-infected patients: use of the CAGE questionnaire. AIDS Res Hum Retrovir. 2004;20(2):151–5.CrossRefPubMed

Galvan FH, Bing EG, Fleishman JA, et al. The prevalence of alcohol consumption and heavy drinking among people with HIV in the United States: results from the HIV cost and services utilization study. J Stud Alcohol. 2002;63(2):179–86.CrossRefPubMed

Burnam MA, Bing EG, Morton SC, et al. Use of mental health and substance abuse treatment services among adults with HIV in the United States. Arch Gen Psychiatry. 2001;58(8):729–36.CrossRefPubMed

Tucker JS, Burnam MA, Sherbourne CD, Kung FY, Gifford AL. Substance use and mental health correlates of nonadherence to antiretroviral medications in a sample of patients with human immunodeficiency virus infection. Am J Med. 2003;114(7):573–80.CrossRefPubMed

Samet JH, Horton NJ, Meli S, Freedberg KA, Palepu A. Alcohol consumption and antiretroviral adherence among HIV-infected persons with alcohol problems. Alcohol Clin Exp Res. 2004;28(4):572–7.CrossRefPubMed

10.

Bazargan-Hejazi S, Bazargan M, Hardin E, Bing EG. Alcohol use and adherence to prescribed therapy among under-served Latino and African-American patients using emergency department services. Ethn Dis. 2005;15(2):267–75.PubMed

11.

Walkup J, Wei W, Sambamoorthi U, Crystal S. Antidepressant treatment and adherence to combination antiretroviral therapy among patients with AIDS and diagnosed depression. Psychiatr Q. 2008;79(1):43–53.CrossRefPubMedPubMedCentral

12.

Parsons JT, Starks TJ, Millar BM, Boonrai K, Marcotte D. Patterns of substance use among HIV-positive adults over 50: implications for treatment and medication adherence. Drug Alcohol Depend. 2014;139:33–40.CrossRefPubMedPubMedCentral

13.

Samet JH, Cheng DM, Libman H, Nunes DP, Alperen JK, Saitz R. Alcohol consumption and HIV disease progression. J Acquir Immune Defic Syndr. 2007;46(2):194–9.CrossRefPubMedPubMedCentral

14.

Chander G, Lau B, Moore RD. Hazardous alcohol use: a risk factor for non-adherence and lack of suppression in HIV infection. J Acquir Immune Defic Syndr. 2006;43(4):411–7.CrossRefPubMedPubMedCentral

15.

Shuper PA, Neuman M, Kanteres F, Baliunas D, Joharchi N, Rehm J. Causal considerations on alcohol and HIV/AIDS—a systematic review. Alcohol Alcohol. 2010;45(2):159–66.CrossRefPubMed

16.

Grant BF, Stinson FS, Dawson DA, et al. Prevalence and co-occurrence of substance use disorders and independent mood and anxiety disorders: results from the national epidemiologic survey on alcohol and related conditions. Arch Gen Psychiatry. 2004;61(8):807–16.CrossRefPubMed

17.

Hasin DS, Goodwin RD, Stinson FS, Grant BF. Epidemiology of major depressive disorder: results from the national epidemiologic survey on alcoholism and related conditions. Arch Gen Psychiatry. 2005;62(10):1097–106.CrossRefPubMed

18.

Stall R, McKusick L, Wiley J, Coates TJ, Ostrow DG. Alcohol and drug use during sexual activity and compliance with safe sex guidelines for AIDS: the AIDS behavioral research project. Health Educ Q. 1986;13(4):359–71.CrossRefPubMed

19.

Theall KP, Clark RA, Powell A, Smith H, Kissinger P. Alcohol consumption, ART usage and high-risk sex among women infected with HIV. AIDS Behav. 2007;11(2):205–15.CrossRefPubMed

20.

Kessler RC, McGonagle KA, Zhao S, et al. Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Results from the national comorbidity survey. Arch Gen Psychiatry. 1994;51(1):8–19.CrossRefPubMed

21.

Ciesla JA, Roberts JE. Meta-analysis of the relationship between HIV infection and risk for depressive disorders. Am J Psychiatry. 2001;158(5):725–30.CrossRefPubMed

22.

Komiti A, Judd F, Grech P, et al. Depression in people living with HIV/AIDS attending primary care and outpatient clinics. Aust N Z J Psychiatry. 2003;37(1):70–7.CrossRefPubMed

23.

Horberg MA, Silverberg MJ, Hurley LB, et al. Effects of depression and selective serotonin reuptake inhibitor use on adherence to highly active antiretroviral therapy and on clinical outcomes in HIV-infected patients. J Acquir Immune Defic Syndr. 2008;47(3):384–90.CrossRefPubMed

24.

Starace F, Ammassari A, Trotta MP, et al. Depression is a risk factor for suboptimal adherence to highly active antiretroviral therapy. J Acquir Immune Defic Syndr. 2002;31(Suppl 3):S136–9.CrossRefPubMed

25.

Cook JA, Cohen MH, Burke J, et al. Effects of depressive symptoms and mental health quality of life on use of highly active antiretroviral therapy among HIV-seropositive women. J Acquir Immune Defic Syndr. 2002;30(4):401–9.CrossRefPubMed

26.

Cruess DG, Petitto JM, Leserman J, et al. Depression and HIV infection: impact on immune function and disease progression. CNS Spectr. 2003;8(1):52–8.CrossRefPubMed

27.

Evans DL, Ten Have TR, Douglas SD, et al. Association of depression with viral load, CD8 T lymphocytes, and natural killer cells in women with HIV infection. Am J Psychiatry. 2002;159(10):1752–9.CrossRefPubMed

28.

Cook JA, Grey D, Burke J, et al. Depressive symptoms and AIDS-related mortality among a multisite cohort of HIV-positive women. Am J Public Health. 2004;94(7):1133–40.CrossRefPubMedPubMedCentral

29.

Sullivan LE, Saitz R, Cheng DM, Libman H, Nunes D, Samet JH. The impact of alcohol use on depressive symptoms in human immunodeficiency virus-infected patients. Addiction. 2008;103(9):1461–7.CrossRefPubMedPubMedCentral

30.

Bryant VE, Whitehead NE, Burrell LE 2nd, et al. Depression and apathy among people living with HIV: implications for treatment of HIV associated neurocognitive disorders. AIDS Behav. 2015;19(8):1430–7.CrossRefPubMedPubMedCentral

31.

Esser MB, Hedden SL, Kanny D, Brewer RD, Gfroerer JC, Naimi TS. Prevalence of alcohol dependence among US adult drinkers, 2009–2011. Prev Chronic Dis. 2014;11:E206.CrossRefPubMedPubMedCentral

32.

Stahre M, Roeber J, Kanny D, Brewer RD, Zhang X. Contribution of excessive alcohol consumption to deaths and years of potential life lost in the United States. Prev Chronic Dis. 2014;11:E109.CrossRefPubMedPubMedCentral

33.

Wen XJ, Balluz L, Town M. Prevalence of HIV risk behaviors between binge drinkers and non-binge drinkers aged 18- to 64-years in US, 2008. J Community Health. 2012;37(1):72–9.CrossRefPubMed

34.

Durham MD, Hart R, Buchacz K, et al. Antiretroviral nonadherence and condomless sex in the HIV outpatient study, USA, 2007–2014. Int J STD AIDS. 2017;. https://doi.org/10.1177/0956462417720547.PubMed

35.

Smart RG, Adlaf EM, Knoke D. Use of the CAGE scale in a population survey of drinking. J Stud Alcohol. 1991;52(6):593–6.CrossRefPubMed

36.

Hasin DS, Aharonovich E, O’Leary A, et al. Reducing heavy drinking in HIV primary care: a randomized trial of brief intervention, with and without technological enhancement. Addiction. 2013;108(7):1230–40.CrossRefPubMedPubMedCentral

37.

First MB, Spitzer RL, Gibbon M, Williams JBW. Structured clinical interview for DSM-IV axis I disorders, research version, non-patient edition (SCID-I/NP). New York: Biometrics Research, New York State Psychiatric Institute; 2002.

38.

Beck AT, Steer RA, Brown GK. Manual for the Beck Depression Inventory-II. San Antonio: Psychological Corporation; 1996.

39.

Reitan R, Wolfson D. The Halstead–Reitan neuropsychological test battery: theory and clinical interpretation. 2nd ed. Tucson: Neuropsychology Press; 1992.

40.

Brantley PJ, Dutton GR, Wood KB. The Beck Depression Inventory—II (BDI–II) and the Beck Depression Inventory—primary care (BDI–PC). In: Maruish ME, editor. The use of psychological testing for treatment planning and assessment outcome. 3rd ed. Mahwah: Erlbaum; 2004. p. 313–26.

41.

Hobkirk AL, Starosta AJ, De Leo JA, et al. Psychometric validation of the BDI-II among HIV-positive CHARTER study participants. Psychol Assess. 2015;27(2):457–66.CrossRefPubMed

42.

Dozois DJA, Covin R. The Beck Depression Inventory-II, beck hopelessness scale, and beck scale for suicide ideation. In: Hersen M, Segal DL, Hilsenroth M, editors. Comprehensive handbook of psychological assessment, personality assessment, vol. 2. Hoboken: Wiley; 2004.

43.

Wiebe JS, Penley JA. A psychometric comparison of the Beck Depression Inventory-II in English and Spanish. Psychol Assess. 2005;17(4):481–5.CrossRefPubMed

44.

Steer RA, Ball R, Ranieri WF, Beck AT. Further evidence for the construct validity of the Beck Depression Inventory-II with psychiatric outpatients. Psychol Rep. 1997;80(2):443–6.CrossRefPubMed

45.

Arbisi PA. Review of the Beck Depression Inventory-II. In: Plake BS, Impara JC, editors. The fourteenth mental measurements yearbook. Lincoln: Buros Institute of Mental Measurements; 2001.

46.

Grothe KB, Dutton GR, Jones GN, Bodenlos J, Ancona M, Brantley PJ. Validation of the Beck Depression Inventory-II in a low-income African American sample of medical outpatients. Psychol Assess. 2005;17(1):110–4.CrossRefPubMed

47.

Penley JA, Wiebe JS, Nwosu A. Psychometric properties of the Spanish Beck Depression Inventory-II in a medical sample. Psychol Assess. 2003;15(4):569–77.CrossRefPubMed

48.

Grant BF, Dawson DA, Hasin DS. The Alcohol use disorder and associated disabilities interview schedule-DSM-IV version. Bethesda: National Institute on Alcohol Abuse and Alcoholism; 2001.

49.

National Institute on Alcohol Abuse and Alcoholism. Drinking levels defined. https://www.niaaa.nih.gov/alcohol-health/overview-alcohol-consumption/moderate-binge-drinking.

50.

Cottler LB, Grant BF, Blaine J, et al. Concordance of DSM-IV alcohol and drug use disorder criteria and diagnoses as measured by AUDADIS-ADR, CIDI and SCAN. Drug Alcohol Depend. 1997;47(3):195–205.CrossRefPubMed

51.

Hasin D, Carpenter KM, McCloud S, Smith M, Grant BF. The alcohol use disorder and associated disabilities interview schedule (AUDADIS): reliability of alcohol and drug modules in a clinical sample. Drug Alcohol Depend. 1997;44(2–3):133–41.CrossRefPubMed

52.

Grant BF, Harford TC, Dawson DA, Chou PS, Pickering RP. The Alcohol use disorder and associated disabilities interview schedule (AUDADIS): reliability of alcohol and drug modules in a general population sample. Drug Alcohol Depend. 1995;39(1):37–44.CrossRefPubMed

53.

Grant BF, Dawson DA, Stinson FS, Chou PS, Kay W, Pickering R. The alcohol use disorder and associated disabilities interview schedule-IV (AUDADIS-IV): reliability of alcohol consumption, tobacco use, family history of depression and psychiatric diagnostic modules in a general population sample. Drug Alcohol Depend. 2003;71(1):7–16.CrossRefPubMed

54.

Canino G, Bravo M, Ramirez R, et al. The Spanish alcohol use disorder and associated disabilities interview schedule (AUDADIS): reliability and concordance with clinical diagnoses in a Hispanic population. J Stud Alcohol. 1999;60(6):790–9.CrossRefPubMed

55.

SAS Institute Inc. SAS/STAT^® software, Version 9.3. 2011.

56.

Sullivan LE, Goulet JL, Justice AC, Fiellin DA. Alcohol consumption and depressive symptoms over time: a longitudinal study of patients with and without HIV infection. Drug Alcohol Depend. 2011;117(2–3):158–63.CrossRefPubMedPubMedCentral

Title: A Cross-Sectional Study of Depressive Symptoms and Risky Alcohol Use Behaviors Among HIV Primary Care Patients in New York City
Authors: Yasemin Algur
Jennifer C. Elliott
Efrat Aharonovich
Deborah S. Hasin
Publication date: 01-05-2018
Publisher: Springer US
Published in: AIDS and Behavior / Issue 5/2018
Print ISSN: 1090-7165
Electronic ISSN: 1573-3254
DOI: https://doi.org/10.1007/s10461-017-1986-0

ACC 2024 Congress Coverage

Heart Failure Video

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

A Cross-Sectional Study of Depressive Symptoms and Risky Alcohol Use Behaviors Among HIV Primary Care Patients in New York City

Abstract

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

Incentivised to exercise

New intervention for STEMI-related cardiogenic shock

» View more highlights on the ACC 2024 congress hub page

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Please log in to get access to this content

Other articles of this Issue 5/2018

Gender Moderates the Association of Depressive Symptoms to Sexual Risk Behavior Among HIV-Positive African-American Outpatients

A Longitudinal Analysis of the Impact of Physical Activity on Neurocognitive Functioning Among HIV-Infected Adults

Positive Psychological Factors are Linked to Successful Cognitive Aging Among Older Persons Living with HIV/AIDS

Memory Impairment in HIV-Infected Individuals with Early and Late Initiation of Regular Marijuana Use

Loneliness in Older Adults Living with HIV

Measurements of Sexuality-Based Stigma among Gay, Bisexual, and Other Men Who Have Sex with Men (GBMSM) in Resource-Poor Settings: A Review

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

Incentivised to exercise

New intervention for STEMI-related cardiogenic shock

» View more highlights on the ACC 2024 congress hub page