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Published in:

01-03-2018 | Original Paper

Influence of Side Effects on ART Adherence Among PLWH in China: The Moderator Role of ART-Related Knowledge

Authors: Guangyu Zhou, Xiaoming Li, Shan Qiao, Zhiyong Shen, Yuejiao Zhou

Published in: AIDS and Behavior | Issue 3/2018

Abstract

Despite the medical advancements in HIV treatment, realities of side effects are faced by people living with HIV (PLWH) who receive antiretroviral therapy (ART). Mixed findings have been reported on the association between side effects and ART adherence. However, few studies have explored the combined side effects and behavior-related information on medication adherence. The aim of the current study is to examine moderator role of ART-related knowledge between side effects and ART adherence. A cross-sectional survey was conducted among 2987 PLWH from October 2012 to August 2013 in China. Of the total sample, 2095 patients had received ART and provided ART adherence. Side effects, ART-related knowledge, and ART adherence, as well as potential covariates were assessed. The results revealed that there was a negative relationship of side effects and ART adherence existed among low and medium levels of ART-related knowledge, but not among high level of knowledge. Future interventions to promote HIV medication adherence should focus on providing behavior-related information education among PLWH.

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Title: Influence of Side Effects on ART Adherence Among PLWH in China: The Moderator Role of ART-Related Knowledge
Authors: Guangyu Zhou
Xiaoming Li
Shan Qiao
Zhiyong Shen
Yuejiao Zhou
Publication date: 01-03-2018
Publisher: Springer US
Published in: AIDS and Behavior / Issue 3/2018
Print ISSN: 1090-7165
Electronic ISSN: 1573-3254
DOI: https://doi.org/10.1007/s10461-017-1791-9

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