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AIDS and Behavior
Published in: AIDS and Behavior 3/2015

01-03-2015 | Original Paper

Daily Associations Between Alcohol Use and Unprotected Anal Sex Among Heavy Drinking HIV-Positive Men Who Have Sex with Men

Authors: Christopher W. Kahler, Tyler B. Wray, David W. Pantalone, Ryan D. Kruis, Nadine R. Mastroleo, Peter M. Monti, Kenneth H. Mayer

Published in: AIDS and Behavior | Issue 3/2015

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Abstract

Men who have sex with men (MSM) account for the largest proportion of new HIV infections in the United States. Alcohol may facilitate HIV transmission by increasing unprotected anal sex, but few studies have focused on transmission behaviors in HIV-positive MSM. This study explored daily associations between alcohol use and sexual behavior among heavy drinking HIV-positive MSM using a 30-day Timeline Followback interview. Results of generalized estimating equations indicated that greater alcohol consumption on a given day was associated with a linear increase in the odds of having unprotected anal sex with partners of any HIV status. However, the odds of reporting unprotected anal sex with HIV-negative or HIV-status unknown partners increased in a curvilinear fashion, occurring primarily at very heavy levels of use (12+ drinks). Results suggest that very heavy drinking increases the risk of engaging in sexual behavior that has the potential for transmitting HIV to other men.
Literature
1.
Centers for Disease Control and Prevention. Estimated HIV incidence in the United States, 2007–2010. Atlanta, GA: U.S. Department of Health and Human Services; 2012.
2.
Centers for Disease Control and Prevention. HIV Among Gay and Bisexual Men. Atlanta, GA: National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention; 2013.
3.
Centers for Disease Control and Prevention. Estimates of New HIV Infections in the United States. Atlanta, GA: National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention; 2008.
4.
Sullivan PS, Hamouda O, Delpech V, et al. Reemergence of the HIV epidemic among men who have sex with men in North America, Western Europe, and Australia, 1996–2005. Ann Epidemiol. 2009;19(6):423–31.CrossRefPubMed
5.
World Health Organization, ed. Prevention and treatment of HIV and other sexually-transmitted infections among men who have sex with men and transgender people: recommendations for a public health approach. Geneva: WHO; 2011. HIV/AIDs Do.
6.
Chander G. Addressing alcohol use in HIV-infected persons. Top Antivir Med. 2011;19(4):143.PubMed
7.
Schneider M, Chersich M, Neuman M, Parry C. Alcohol consumption and HIV/AIDS: the neglected interface. Addiction. 2012;107(8):1369–71.CrossRefPubMed
8.
Sander PM, Cole SR, Stall RD, et al. Joint effects of alcohol consumption and high-risk sexual behavior on HIV seroconversion among men who have sex with men. AIDS. 2013;27(5):815–23.CrossRefPubMedCentralPubMed
9.
10.
Cooper ML. Does drinking promote risky sexual behavior? A complex answer to a simple question. Curr Dir Psychol Sci. 2006;15(1):19–23.CrossRef
11.
Wechsler H, Lee JE, Kuo M, Lee H. College binge drinking in the 1990s: a continuing problem results of the Harvard School of Public Health 1999 College Alcohol Study. J Am Coll Health. 2000;48(5):199–210.CrossRefPubMed
12.
Abbey A, Parkhill MR, Buck PO, Saenz C. Condom use with a casual partner: what distinguishes college students’ use when intoxicated? Psychol Addict Behav. 2007;21(1):76.CrossRefPubMed
13.
Rehm J, Shield KD, Joharchi N, Shuper PA. Alcohol consumption and the intention to engage in unprotected sex: systematic review and meta-analysis of experimental studies. Addiction. 2012;107(1):51–9.CrossRefPubMed
14.
Leigh BC, Vanslyke JG, Hoppe MJ, Rainey DT, Morrison DM, Gillmore MR. Drinking and condom use: results from an event-based daily diary. AIDS Behav. 2008;12(1):104–12.CrossRefPubMedCentralPubMed
15.
16.
Weinhardt LS, Carey MP. Does alcohol lead to sexual risk behavior? Findings from event-level research. Annu Rev Sex Res. 2000;11(1):125–57.PubMedCentralPubMed
17.
Leigh BC. Alcohol and condom use: a meta-analysis of event-level studies. Sex Transm Dis. 2002;29(8):476–82.CrossRefPubMed
18.
19.
van Griensven F, van Wijngaarden JWdL, Baral S, Grulich A. The global epidemic of HIV infection among men who have sex with men. Curr Opin HIV AIDS 2009;4:300–7.
20.
Bruce D, Kahana S, Harper GW, Fernández MI, ATN t. Alcohol use predicts sexual risk behavior with HIV-negative or partners of unknown status among young HIV-positive men who have sex with men. AIDS Care. 2013;25(5):559–65.CrossRefPubMedCentralPubMed
21.
Hirshfield S, Remien RH, Humberstone M, Walavalkar I, Chiasson MA. Substance use and high-risk sex among men who have sex with men: a national online study in the USA. AIDS Care. 2004;16(8):1036–47.CrossRefPubMed
22.
Koblin BA, Chesney MA, Husnik MJ, et al. High-risk behaviors among men who have sex with men in 6 US cities: baseline data from the EXPLORE Study. Am J Public Health. 2003;93(6):926–32.CrossRefPubMedCentralPubMed
23.
Pantalone DW, Huh D, Nelson KM, Pearson CR, Simoni JM. Prospective predictors of unprotected anal intercourse among HIV-seropositive men who have sex with men initiating antiretroviral therapy. AIDS Behav. 2014;18(1):78–87.CrossRefPubMed
24.
Clutterbuck DJ, Gorman D, McMillan A, Lewis R, Macintyre CA. Substance use and unsafe sex amongst homosexual men in Edinburgh. AIDS Care. 2001;13(4):527–35.CrossRefPubMed
25.
Chiasson MA, Hirshfield S, Remien RH, Humberstone M, Wong T, Wolitski RJ. A comparison of on-line and off-line sexual risk in men who have sex with men: an event-based on-line survey. J Acquir Immune Defic Syndr. 2007;44(2):235–43.CrossRefPubMed
26.
Prestage G, Van de Ven P, Mao L, Grulich A, Kippax S, Kaldor J. Contexts for last occasions of unprotected anal intercourse among HIV-negative gay men in Sydney: the health in men cohort. AIDS Care. 2005;17(1):23–32.CrossRefPubMed
27.
Maisto SA, Palfai T, Vanable P, Heath J, Woolf-King S. The effects of alcohol and sexual arousal on determinants of sexual risk in men who have sex with men. Arch Sex Behav. 2012;41(4):971–86.CrossRefPubMedCentralPubMed
28.
Vosburgh HW, Mansergh G, Sullivan PS, Purcell DW. A review of the literature on event-level substance use and sexual risk behavior among men who have sex with men. AIDS Behav. 2012;16(6):1394–410.CrossRefPubMed
29.
First MB, Spitzer RL, Gibbon M, Williams JBW. Structured Clinical Interview for DSM-IV Axis I Disorders. New York: New York State Psychiatric Institute; 1995.
30.
Radloff LS. The CES-D scale: a self-report depression scale for research in the general population. Appl Psychol Meas. 1977;1(Summer):385–401.CrossRef
31.
Sobell MB, Maisto SA, Sobell LC, Cooper AM, Cooper TC, Sanders B. Developing a prototype for evaluating alcohol treatment effectiveness. In: Sobell LC, Sobell MB, Ward E, editors. Evaluating alcohol and drug abuse treatment effectiveness: Recent advances. New York: Pergamon Press; 1980.
32.
Sobell LC, Sobell MB. Convergent validity: an approach to increasing confidence in treatment outcome conclusions with alcohol and drug abusers. In: Sobell LC, Sobell MB, Ward E, editors. Evaluating alcohol and drug abuse treatment effectiveness: recent advances. New York: Pergamon Press; 1980. p. 177–183.
33.
Sobell LC, Sobell MB. Validity of self-reports in three populations of alcoholics. J Consult Clin Psychol. 1979;46:901–7.CrossRef
34.
Fals-Stewart W, O’Farrell TJ, Freitas TT, McFarlin SK, Rutigliano P. The Timeline Followback reports of psychoactive substance use by drug-abusing patients: psychometric properties. J Consult Clin Psychol. 2000;68(1):134–44.CrossRefPubMed
35.
Sobell LC, Maisto SA, Sobell MB, Cooper AM. Reliability of alcohol abusers’ self-reports of drinking behavior. Behav Res Ther. 1979;17:157–60.CrossRefPubMed
36.
Weinhardt LS, Carey MP, Maisto SA, Carey KB, Cohen MM, Wickramasinghe SM. Reliability of the timeline follow-back sexual behavior interview. Ann Behav Med. 1998;20(1):25–30.CrossRefPubMedCentralPubMed
37.
Irwin TW, Morgenstern J, Parsons JT, Wainberg M, Labouvie E. Alcohol and sexual HIV risk behavior among problem drinking men who have sex with men: An event level analysis of timeline followback data. AIDS Behav. 2006;10(3):299–307.CrossRefPubMed
38.
National Institute on Alcohol Abuse and Alcoholism. Helping Patients Who Drink Too Much: A Clinician’s Guide. Rockville, MD: U.S. Department of Health and Human Services; 2005.
39.
Greenfield TK, Ye Y, Bond J, et al. Risks of alcohol use disorders related to drinking patterns in the U.S. general population. J Stud Alcohol Drugs. 2014;75(2):319–27.CrossRefPubMedCentralPubMed
40.
Kalichman SC, Rompa D, Cage M. Distinguishing between overlapping somatic symptoms of depression and HIV disease in people living with HIV-AIDS. J Nerv Ment Dis. 2000;188(10):662–70.CrossRefPubMed
41.
Reisner SL, Mimiaga MJ, Bland S, et al. Problematic alcohol use and HIV risk among Black men who have sex with men in Massachusetts. AIDS Care. 2010;22(5):577–87.CrossRefPubMed
42.
Reisner SL, Mimiaga MJ, Skeer M, et al. Clinically significant depressive symptoms as a risk factor for HIV infection among black MSM in Massachusetts. AIDS Behav. 2009;13(4):798–810.CrossRefPubMedCentralPubMed
43.
Seage GR, Mayer KH, Horsburgh CR, Holmberg SD, Moon MW, Lamb GA. The relation between nitrite inhalants, unprotected receptive anal intercourse, and the risk of human immunodeficiency virus infection. Am J Epidemiol. 1992;135(1):1–11.PubMed
44.
Leigh BC. Alcohol expectancies and reasons for drinking: comments from a study of sexuality. Psychol Addict Behav. 1990;4(2):91.CrossRef
45.
Truong HM, Kellogg T, Klausner J, et al. Increases in sexually transmitted infections and sexual risk behaviour without a concurrent increase in HIV incidence among men who have sex with men in San Francisco: a suggestion of HIV serosorting? Sex Transm Infect. 2006;82(6):461–6.CrossRefPubMedCentralPubMed
46.
47.
Crepaz N, Hart TA, Marks G. Highly active antiretroviral therapy and sexual risk behavior. JAMA. 2004;292(2):224–36.CrossRefPubMed
48.
Leigh BC. Alcohol expectancies and reasons for drinking: comments from a study of sexuality. Psychol Addict Behav. 1990;42:91–6.CrossRef
Metadata
Title
Daily Associations Between Alcohol Use and Unprotected Anal Sex Among Heavy Drinking HIV-Positive Men Who Have Sex with Men
Authors
Christopher W. Kahler
Tyler B. Wray
David W. Pantalone
Ryan D. Kruis
Nadine R. Mastroleo
Peter M. Monti
Kenneth H. Mayer
Publication date
01-03-2015
Publisher
Springer US
Published in
AIDS and Behavior / Issue 3/2015
Print ISSN: 1090-7165
Electronic ISSN: 1573-3254
DOI
https://doi.org/10.1007/s10461-014-0896-7

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