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AIDS and Behavior
Published in: AIDS and Behavior 11/2014

01-11-2014 | Original Paper

Gender-Specific Risk Factors for Virologic Failure in KwaZulu-Natal: Automobile Ownership and Financial Insecurity

Authors: Anna Q. Hare, Claudia E. Ordóñez, Brent A. Johnson, Carlos del Rio, Rachel A. Kearns, Baohua Wu, Jane Hampton, Peng Wu, Henry Sunpath, Vincent C. Marconi

Published in: AIDS and Behavior | Issue 11/2014

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Abstract

We sought to examine which socioeconomic indicators are risk factors for virologic failure among HIV-1 infected patients receiving antiretroviral therapy (ART) in KwaZulu-Natal, South Africa. A case–control study of virologic failure was conducted among patients recruited from the outpatient clinic at McCord Hospital in Durban, South Africa between October 1, 2010 and June 30, 2012. Cases were those failing first-line ART, defined as viral load >1,000 copies/mL. Univariate logistic regression was performed on sociodemographic data for the outcome of virologic failure. Variables found significant (p < 0.05) were used in multivariate models and all models were stratified by gender. Of 158 cases and 300 controls, 35 % were male and median age was 40 years. Gender stratification of models revealed automobile ownership was a risk factor among males, while variables of financial insecurity (unemployment, non-spouse family paying for care, staying with family) were risk factors for women. In this cohort, financial insecurity among women and automobile ownership among men were risk factors for virologic failure. Risk factor differences between genders demonstrate limitations of generalized risk factor analysis.
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Metadata
Title
Gender-Specific Risk Factors for Virologic Failure in KwaZulu-Natal: Automobile Ownership and Financial Insecurity
Authors
Anna Q. Hare
Claudia E. Ordóñez
Brent A. Johnson
Carlos del Rio
Rachel A. Kearns
Baohua Wu
Jane Hampton
Peng Wu
Henry Sunpath
Vincent C. Marconi
Publication date
01-11-2014
Publisher
Springer US
Published in
AIDS and Behavior / Issue 11/2014
Print ISSN: 1090-7165
Electronic ISSN: 1573-3254
DOI
https://doi.org/10.1007/s10461-014-0849-1

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WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

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