Skip to main content
Top
Published in: AIDS and Behavior 4/2014

01-04-2014 | Substantive Review

Evidence Informing the Intersection of HIV, Aging and Health: A Scoping Review

Authors: Lori A. Chambers, Michael G. Wilson, Sergio Rueda, David Gogolishvili, Maggie Qiyun Shi, Sean B. Rourke, The Positive Aging Review Team

Published in: AIDS and Behavior | Issue 4/2014

Login to get access

Abstract

The growing number of people over age 50 with HIV requires research, policy, and practice to develop a more comprehensive understanding of the health consequences of HIV in older individuals. We conducted a scoping review of peer-reviewed and grey literature published since 1996 to explore the impacts of aging on the health of older people with HIV (50 years or older). We included 209 studies (two systematic reviews, 174 quantitative studies, 28 qualitative studies, and five mixed methods studies). Health topics addressed include: HIV- and aging-related comorbidities, disease progression, neurocognitive functioning, mental health conditions, psychological well-being, social supports, stigma, antiretroviral adherence, health care utilization/access, and sexual risk behaviour. We recommend that future research takes a broader view of health, looks at aging from a strength-based perspective and examines the issue using diverse perspectives (i.e., geographic location, multiple methods, time of diagnosis, time on antiretroviral therapy (ART), demographic diversity).
Appendix
Available only for authorised users
Literature
1.
go back to reference Karpiak SE, Shippy RA, Cantor M. Research on older adults with HIV. New York: AIDS Community Research Initiative of America; 2006. Karpiak SE, Shippy RA, Cantor M. Research on older adults with HIV. New York: AIDS Community Research Initiative of America; 2006.
4.
go back to reference Effros RB, Fletcher CV, Gebo K, Halter JB, Hazzard WR, Horne FM, et al. Workshop on HIV infection and aging: what is known and future research directions. Clin Infect Dis. 2008;47(4):542–53.PubMedCentralPubMedCrossRef Effros RB, Fletcher CV, Gebo K, Halter JB, Hazzard WR, Horne FM, et al. Workshop on HIV infection and aging: what is known and future research directions. Clin Infect Dis. 2008;47(4):542–53.PubMedCentralPubMedCrossRef
5.
go back to reference Public Health Agency of Canada. HIV/AIDS Epi Updates N. HIV/AIDS Epi Updates, November 2007. Ottawa: Surveillance and Risk Assessment Division, Centre for Infectious Disease Prevention and Control, Public Health Agency of Canada; 2007. Public Health Agency of Canada. HIV/AIDS Epi Updates N. HIV/AIDS Epi Updates, November 2007. Ottawa: Surveillance and Risk Assessment Division, Centre for Infectious Disease Prevention and Control, Public Health Agency of Canada; 2007.
9.
go back to reference Public Health Agency of Canada. HIV and AIDS in Canada. Surveillance Report to December 31, 2009. Ottawa: Surveillance and Risk Assessment Division, Centre for Communicable Diseases and Infection Control, Public Health Agency of Canada; 2010. Public Health Agency of Canada. HIV and AIDS in Canada. Surveillance Report to December 31, 2009. Ottawa: Surveillance and Risk Assessment Division, Centre for Communicable Diseases and Infection Control, Public Health Agency of Canada; 2010.
10.
go back to reference Health Protection Agency (HPK). HIV in the United Kingdom: 2008 Report. London: HPK; 2008. Health Protection Agency (HPK). HIV in the United Kingdom: 2008 Report. London: HPK; 2008.
12.
go back to reference Pearline RV, Tucker JD, Yuan LF, Bu J, Yin YP, Chen XS, et al. Sexually transmitted infections among individuals over fifty years of age in China. AIDS Patient Care STDs. 2010;24(6):345.PubMedCentralPubMedCrossRef Pearline RV, Tucker JD, Yuan LF, Bu J, Yin YP, Chen XS, et al. Sexually transmitted infections among individuals over fifty years of age in China. AIDS Patient Care STDs. 2010;24(6):345.PubMedCentralPubMedCrossRef
13.
go back to reference Negin J, Cumming RG. HIV infection in older adults in sub-Saharan Africa: extrapolating prevalence from existing data. Bull WHO. 2010;88(11):847–53.PubMedCentralPubMed Negin J, Cumming RG. HIV infection in older adults in sub-Saharan Africa: extrapolating prevalence from existing data. Bull WHO. 2010;88(11):847–53.PubMedCentralPubMed
14.
go back to reference Brasileiro M, Freitas MIF. Social representations about AIDS in people over 50, infected by HIV. Revista Latino-Americana de Enfermagem (RLAE). 2006;14(5):789–95.CrossRef Brasileiro M, Freitas MIF. Social representations about AIDS in people over 50, infected by HIV. Revista Latino-Americana de Enfermagem (RLAE). 2006;14(5):789–95.CrossRef
15.
go back to reference Canadian Working Group on HIV and Rehabilitation. HIV and aging background paper for the partners in Aging National Forum. 6th Canadian HIV/AIDS Skills Building Symposium, Montreal, QC2010, 22 Feb 2010. Canadian Working Group on HIV and Rehabilitation. HIV and aging background paper for the partners in Aging National Forum. 6th Canadian HIV/AIDS Skills Building Symposium, Montreal, QC2010, 22 Feb 2010.
16.
go back to reference Önen NF, Overton ET. HIV and aging: two converging epidemics. Mo Med. 2009;106(4):269–73.PubMed Önen NF, Overton ET. HIV and aging: two converging epidemics. Mo Med. 2009;106(4):269–73.PubMed
17.
go back to reference High KP, Brennan-Ing M, Clifford DB, Cohen MH, Currier J, Deeks SG, et al. HIV and aging: state of knowledge and areas of critical need for research. A report to the NIH Office of AIDS Research by the HIV and aging working group. J Acquir Immune Defic Syndr. 2012;60(Suppl 1):S1–18.PubMedCrossRef High KP, Brennan-Ing M, Clifford DB, Cohen MH, Currier J, Deeks SG, et al. HIV and aging: state of knowledge and areas of critical need for research. A report to the NIH Office of AIDS Research by the HIV and aging working group. J Acquir Immune Defic Syndr. 2012;60(Suppl 1):S1–18.PubMedCrossRef
18.
20.
go back to reference Gonzalez R, Cherner M. Co-factors in HIV neurobehavioural disturbances: substance abuse, hepatitis C and aging. Int Rev Psychiatry. 2008;20(1):49–60.PubMedCrossRef Gonzalez R, Cherner M. Co-factors in HIV neurobehavioural disturbances: substance abuse, hepatitis C and aging. Int Rev Psychiatry. 2008;20(1):49–60.PubMedCrossRef
21.
go back to reference Capeau J. From lipodystrophy and insulin resistance to metabolic syndrome: HIV infection, treatment and aging. Curr Opin HIV AIDS. 2007;2(4):247–52.PubMedCrossRef Capeau J. From lipodystrophy and insulin resistance to metabolic syndrome: HIV infection, treatment and aging. Curr Opin HIV AIDS. 2007;2(4):247–52.PubMedCrossRef
22.
go back to reference Casau NC. Perspective on HIV infection and aging: emerging research on the horizon. Clin Infect Dis. 2005;41(6):855–63.PubMedCrossRef Casau NC. Perspective on HIV infection and aging: emerging research on the horizon. Clin Infect Dis. 2005;41(6):855–63.PubMedCrossRef
23.
go back to reference Smith RD, Delpech VC, Brown AE, Rice BD. HIV transmission and high rates of late diagnoses among adults aged 50 years and over. AIDS. 2010;24(13):2109–15.PubMedCrossRef Smith RD, Delpech VC, Brown AE, Rice BD. HIV transmission and high rates of late diagnoses among adults aged 50 years and over. AIDS. 2010;24(13):2109–15.PubMedCrossRef
24.
go back to reference Mutevedzi PC, Lessells RJ, Rodger AJ, Newell M-L. Association of age with mortality and virological and immunological response to antiretroviral therapy in rural South African adults. PLoS One. 2011;6(7):e21795.PubMedCentralPubMedCrossRef Mutevedzi PC, Lessells RJ, Rodger AJ, Newell M-L. Association of age with mortality and virological and immunological response to antiretroviral therapy in rural South African adults. PLoS One. 2011;6(7):e21795.PubMedCentralPubMedCrossRef
25.
go back to reference Althoff K, Justice A, Gange S, Deeks S, Saag M, Silverberg M, et al. Virologic and immunologic response to HAART, by age and regimen class. AIDS. 2010;24(16):2469–79.PubMedCentralPubMedCrossRef Althoff K, Justice A, Gange S, Deeks S, Saag M, Silverberg M, et al. Virologic and immunologic response to HAART, by age and regimen class. AIDS. 2010;24(16):2469–79.PubMedCentralPubMedCrossRef
26.
go back to reference Grabar S, Kousignian I, Sobel A, Le Bras P, Gasnault J, Enel P, et al. Immunologic and clinical responses to highly active antiretroviral therapy over 50 years of age. Results from the French Hospital Database on HIV. AIDS. 2004;18(15):2029–38.PubMedCrossRef Grabar S, Kousignian I, Sobel A, Le Bras P, Gasnault J, Enel P, et al. Immunologic and clinical responses to highly active antiretroviral therapy over 50 years of age. Results from the French Hospital Database on HIV. AIDS. 2004;18(15):2029–38.PubMedCrossRef
27.
go back to reference Peate I. Human immunodeficiency virus and the older person. Br J Nurs. 2007;16(10):606–10.PubMed Peate I. Human immunodeficiency virus and the older person. Br J Nurs. 2007;16(10):606–10.PubMed
28.
go back to reference Vance DE, Struzick TC. Addressing risk factors of cognitive impairment in adults aging with HIV: a social work model. J Gerontol Soc Work. 2007;49(4):51–77.PubMedCrossRef Vance DE, Struzick TC. Addressing risk factors of cognitive impairment in adults aging with HIV: a social work model. J Gerontol Soc Work. 2007;49(4):51–77.PubMedCrossRef
29.
go back to reference Valcour V, Shikuma C, Shiramizu B, Watters M, Poff P, Selnes O, et al. Higher frequency of dementia in older HIV-1 individuals: the Hawaii aging with HIV-1 cohort. Neurology. 2004;63(5):822–7.PubMedCentralPubMedCrossRef Valcour V, Shikuma C, Shiramizu B, Watters M, Poff P, Selnes O, et al. Higher frequency of dementia in older HIV-1 individuals: the Hawaii aging with HIV-1 cohort. Neurology. 2004;63(5):822–7.PubMedCentralPubMedCrossRef
30.
go back to reference McMurtray A, Nakamoto B, Shikuma C, Valcour V. Cortical atrophy and white matter hyperintensities in HIV: the Hawaii Aging with HIV Cohort Study. J Stroke Cerebrovasc Dis. 2008;17(4):212–7.PubMedCentralPubMedCrossRef McMurtray A, Nakamoto B, Shikuma C, Valcour V. Cortical atrophy and white matter hyperintensities in HIV: the Hawaii Aging with HIV Cohort Study. J Stroke Cerebrovasc Dis. 2008;17(4):212–7.PubMedCentralPubMedCrossRef
31.
go back to reference Valcour V, Shikuma C, Shiramizu B, Watters M, Poff P, Selnes OA, et al. Age, apolipoprotein E4, and the risk of HIV dementia: the Hawaii aging with HIV cohort. J Neuroimmunol. 2004;157(1–2 Spec Iss):197–202.PubMedCrossRef Valcour V, Shikuma C, Shiramizu B, Watters M, Poff P, Selnes OA, et al. Age, apolipoprotein E4, and the risk of HIV dementia: the Hawaii aging with HIV cohort. J Neuroimmunol. 2004;157(1–2 Spec Iss):197–202.PubMedCrossRef
32.
go back to reference Vance DE, Moneyham L, Farr KF. Suicidal ideation in adults aging with HIV: neurological and cognitive considerations. J Psychosoc Nurs Ment Health Serv. 2008;46(11):33–8.PubMedCrossRef Vance DE, Moneyham L, Farr KF. Suicidal ideation in adults aging with HIV: neurological and cognitive considerations. J Psychosoc Nurs Ment Health Serv. 2008;46(11):33–8.PubMedCrossRef
33.
go back to reference Heckman TG, Kochman A, Sikkema KJ. Depressive symptoms in older adults living with HIV disease: application of the chronic illness quality of life model. J Ment Health Aging. 2002;8(4):267–79. Heckman TG, Kochman A, Sikkema KJ. Depressive symptoms in older adults living with HIV disease: application of the chronic illness quality of life model. J Ment Health Aging. 2002;8(4):267–79.
34.
go back to reference Shippy RA, Karpiak SE. Aging HIV/AIDS population: fragile social networks. Aging Ment Health. 2005;9(3):246–54.PubMedCrossRef Shippy RA, Karpiak SE. Aging HIV/AIDS population: fragile social networks. Aging Ment Health. 2005;9(3):246–54.PubMedCrossRef
35.
go back to reference Emlet CA. An examination of the social networks and social isolation in older and younger adults living with HIV/AIDS. Health Soc Work. 2006;31(4):299–308.PubMedCrossRef Emlet CA. An examination of the social networks and social isolation in older and younger adults living with HIV/AIDS. Health Soc Work. 2006;31(4):299–308.PubMedCrossRef
36.
go back to reference Vance DE, Moneyham L, Fordham P, Struzick TC. A model of suicidal ideation in adults aging with HIV. J Assoc Nurses AIDS Care. 2008;5:375–84.CrossRef Vance DE, Moneyham L, Fordham P, Struzick TC. A model of suicidal ideation in adults aging with HIV. J Assoc Nurses AIDS Care. 2008;5:375–84.CrossRef
37.
go back to reference Shippy RA, Karpiak SE. Perceptions of support among older adults with HIV. Res Aging. 2005;27(3):290–306.CrossRef Shippy RA, Karpiak SE. Perceptions of support among older adults with HIV. Res Aging. 2005;27(3):290–306.CrossRef
38.
go back to reference Vance DE, Woodley RA. Strengths and distress in adults who are aging with HIV: a pilot study. Psychol Rep. 2005;96(2):383–6.PubMedCrossRef Vance DE, Woodley RA. Strengths and distress in adults who are aging with HIV: a pilot study. Psychol Rep. 2005;96(2):383–6.PubMedCrossRef
39.
go back to reference Schrimshaw EW, Siegel K. Perceived barriers to social support from family and friends among older adults with HIV/AIDS. J Health Psychol. 2003;8(6):738–52.PubMedCrossRef Schrimshaw EW, Siegel K. Perceived barriers to social support from family and friends among older adults with HIV/AIDS. J Health Psychol. 2003;8(6):738–52.PubMedCrossRef
41.
go back to reference Schick V, Herbenick D, Reece M, Sanders SA, Dodge B, Middlestadt SE, et al. Sexual behaviors, condom use, and sexual health of Americans over 50: implications for sexual health promotion for older adults. J Sex Med. 2010;7:315–29.PubMedCrossRef Schick V, Herbenick D, Reece M, Sanders SA, Dodge B, Middlestadt SE, et al. Sexual behaviors, condom use, and sexual health of Americans over 50: implications for sexual health promotion for older adults. J Sex Med. 2010;7:315–29.PubMedCrossRef
42.
go back to reference Lindau ST, Schumm LP, Laumann EO, Levinson W, O’Muircheartaigh CA, Waite LJ. A study of sexuality and health among older adults in the United States. New Engl J Med. 2007;357(8):762–74.PubMedCentralPubMedCrossRef Lindau ST, Schumm LP, Laumann EO, Levinson W, O’Muircheartaigh CA, Waite LJ. A study of sexuality and health among older adults in the United States. New Engl J Med. 2007;357(8):762–74.PubMedCentralPubMedCrossRef
43.
go back to reference Lovejoy TI, Heckman TG, Sikkema KJ, Hansen NB, Kochman A, Suhr JA, et al. Patterns and correlates of sexual activity and condom use behavior in persons 50-plus years of age living with HIV/AIDS. AIDS Behav. 2008;6:943–56.CrossRef Lovejoy TI, Heckman TG, Sikkema KJ, Hansen NB, Kochman A, Suhr JA, et al. Patterns and correlates of sexual activity and condom use behavior in persons 50-plus years of age living with HIV/AIDS. AIDS Behav. 2008;6:943–56.CrossRef
44.
go back to reference Cooperman NA, Arnsten JH, Klein RS. Current sexual activity and risky sexual behavior in older men with or at risk for HIV infection. AIDS Educ Prev. 2007;19(4):321–33.PubMedCentralPubMedCrossRef Cooperman NA, Arnsten JH, Klein RS. Current sexual activity and risky sexual behavior in older men with or at risk for HIV infection. AIDS Educ Prev. 2007;19(4):321–33.PubMedCentralPubMedCrossRef
45.
go back to reference Crum NF, Furtek KJ, Olson PE, Amling CL, Wallace MR. A review of hypogonadism and erectile dysfunction among HIV-infected men during the pre- and post-HAART eras: diagnosis, pathogenesis, and management. AIDS Patient Care STDs. 2005;19(10):655–71.PubMedCrossRef Crum NF, Furtek KJ, Olson PE, Amling CL, Wallace MR. A review of hypogonadism and erectile dysfunction among HIV-infected men during the pre- and post-HAART eras: diagnosis, pathogenesis, and management. AIDS Patient Care STDs. 2005;19(10):655–71.PubMedCrossRef
46.
go back to reference Centers for Disease Control and Prevention. CDC HIV/AIDS Facts: HIV/AIDS among persons aged 50 and older [Fact Sheet]. Atlanta: US: DHHS, CDC, 2008. Centers for Disease Control and Prevention. CDC HIV/AIDS Facts: HIV/AIDS among persons aged 50 and older [Fact Sheet]. Atlanta: US: DHHS, CDC, 2008.
47.
go back to reference Arksey H, O’Malley L. Scoping studies: towards a methodological framework. Int J Soc Res Methodol. 2005;8(1):19–32.CrossRef Arksey H, O’Malley L. Scoping studies: towards a methodological framework. Int J Soc Res Methodol. 2005;8(1):19–32.CrossRef
48.
go back to reference Mays N, Roberts E, Popay J. Synthesising research evidence. In: Fulop N, Allen P, Clarke A, Black N, editors. Studying the organisation and delivery of health services: research methods. London: Routlidge; 2001. p. 188–220. Mays N, Roberts E, Popay J. Synthesising research evidence. In: Fulop N, Allen P, Clarke A, Black N, editors. Studying the organisation and delivery of health services: research methods. London: Routlidge; 2001. p. 188–220.
49.
50.
go back to reference Shea B, Grimshaw J, Wells G, Boers M, Andersson N, Hamel C, et al. Development of AMSTAR: a measurement tool to assess the methodological quality of systematic reviews. BMC Med Res Methodol. 2007;7(1):10–6.PubMedCentralPubMedCrossRef Shea B, Grimshaw J, Wells G, Boers M, Andersson N, Hamel C, et al. Development of AMSTAR: a measurement tool to assess the methodological quality of systematic reviews. BMC Med Res Methodol. 2007;7(1):10–6.PubMedCentralPubMedCrossRef
51.
go back to reference Oxman AD, Fretheim A, Schünemann HJ. Improving the use of research evidence in guideline development: introduction. Health Res Policy Syst. 2006;4(1):12.PubMedCentralPubMedCrossRef Oxman AD, Fretheim A, Schünemann HJ. Improving the use of research evidence in guideline development: introduction. Health Res Policy Syst. 2006;4(1):12.PubMedCentralPubMedCrossRef
53.
go back to reference Kearney F, Moore AR, Donegan CF, Lambert J. The ageing of HIV: implications for geriatric medicine. Age Ageing. 2010;39(5):536–41.PubMedCrossRef Kearney F, Moore AR, Donegan CF, Lambert J. The ageing of HIV: implications for geriatric medicine. Age Ageing. 2010;39(5):536–41.PubMedCrossRef
54.
go back to reference Sankar A, Nevedal A, Neufeld S, Berry R, Luborsky M. What do we know about older adults and HIV? A review of social and behavioral literature. AIDS Care. 2011;23(10):1187–207.PubMedCentralPubMedCrossRef Sankar A, Nevedal A, Neufeld S, Berry R, Luborsky M. What do we know about older adults and HIV? A review of social and behavioral literature. AIDS Care. 2011;23(10):1187–207.PubMedCentralPubMedCrossRef
56.
go back to reference Brennan M, Strauss SM, Karpiak SE. Religious congregations and the growing needs of older adults with HIV. J Relig Spiritual Aging. 2010;22(4):307–28.CrossRef Brennan M, Strauss SM, Karpiak SE. Religious congregations and the growing needs of older adults with HIV. J Relig Spiritual Aging. 2010;22(4):307–28.CrossRef
57.
go back to reference Poindexter CC, Shippy RA. HIV diagnosis disclosure: stigma management and stigma Resistance. J Gerontol Soc Work. 2010;53(4):366–81.PubMedCrossRef Poindexter CC, Shippy RA. HIV diagnosis disclosure: stigma management and stigma Resistance. J Gerontol Soc Work. 2010;53(4):366–81.PubMedCrossRef
58.
go back to reference Grov C, Golub SA, Parsons JT, Brennan M, Karpiak SE. Loneliness and HIV-related stigma explain depression among older HIV-positive adults. AIDS Care. 2010;22(5):630–9.PubMedCentralPubMedCrossRef Grov C, Golub SA, Parsons JT, Brennan M, Karpiak SE. Loneliness and HIV-related stigma explain depression among older HIV-positive adults. AIDS Care. 2010;22(5):630–9.PubMedCentralPubMedCrossRef
59.
go back to reference Poindexter C, Shippy RA. Networks of older New Yorkers with HIV: fragility, resilience, and transformation. AIDS Patient Care STDs. 2008;22(9):723–33.PubMedCrossRef Poindexter C, Shippy RA. Networks of older New Yorkers with HIV: fragility, resilience, and transformation. AIDS Patient Care STDs. 2008;22(9):723–33.PubMedCrossRef
60.
go back to reference Golub SA, Tomassilli JC, Pantalone DW, Brennan M, Karpiak SE, Parsons JT. Prevalence and correlates of sexual behavior and risk management among HIV-positive adults over 50. Sex Transm Dis. 2010;37(10):615.PubMed Golub SA, Tomassilli JC, Pantalone DW, Brennan M, Karpiak SE, Parsons JT. Prevalence and correlates of sexual behavior and risk management among HIV-positive adults over 50. Sex Transm Dis. 2010;37(10):615.PubMed
61.
go back to reference Sacktor N, Skolasky R, Selnes OA, Watters M, Poff P, Shiramizu B, et al. Neuropsychological test profile differences between young and old human immunodeficiency virus-positive individuals. J Neurovirol. 2007;13(3):203–9.PubMedCrossRef Sacktor N, Skolasky R, Selnes OA, Watters M, Poff P, Shiramizu B, et al. Neuropsychological test profile differences between young and old human immunodeficiency virus-positive individuals. J Neurovirol. 2007;13(3):203–9.PubMedCrossRef
62.
go back to reference Valcour V, Watters M, Williams A, Sacktor N, McMurtray A, Shikuma C. Aging exacerbates extrapyramidal motor signs in the era of highly active antiretroviral therapy. J Neurovirol. 2008;14(5):362–7.PubMedCentralPubMedCrossRef Valcour V, Watters M, Williams A, Sacktor N, McMurtray A, Shikuma C. Aging exacerbates extrapyramidal motor signs in the era of highly active antiretroviral therapy. J Neurovirol. 2008;14(5):362–7.PubMedCentralPubMedCrossRef
63.
go back to reference Valcour V, Yee P, Williams AE, Shiramizu B, Watters M, Selnes O, et al. Lowest ever CD4 lymphocyte count (CD4 nadir) as a predictor of current cognitive and neurological status in human immunodeficiency virus type 1 infection—the Hawaii aging with HIV cohort. J Neurovirol. 2006;12(5):387–91.PubMedCrossRef Valcour V, Yee P, Williams AE, Shiramizu B, Watters M, Selnes O, et al. Lowest ever CD4 lymphocyte count (CD4 nadir) as a predictor of current cognitive and neurological status in human immunodeficiency virus type 1 infection—the Hawaii aging with HIV cohort. J Neurovirol. 2006;12(5):387–91.PubMedCrossRef
64.
go back to reference Watters MR, Poff PW, Shiramizu BT, Holck PS, Fast KMS, Shikuma CM, et al. Symptomatic distal sensory polyneuropathy in HIV after age 50. Neurology. 2004;62(8):1378–83.PubMedCrossRef Watters MR, Poff PW, Shiramizu BT, Holck PS, Fast KMS, Shikuma CM, et al. Symptomatic distal sensory polyneuropathy in HIV after age 50. Neurology. 2004;62(8):1378–83.PubMedCrossRef
65.
go back to reference McMurtray A, Nakamoto B, Shikuma C, Valcour V. Small-vessel vascular disease in human immunodeficiency virus infection: the Hawaii aging with HIV cohort study. Cerebrovasc Dis. 2007;24(2–3):236–41.PubMedCrossRef McMurtray A, Nakamoto B, Shikuma C, Valcour V. Small-vessel vascular disease in human immunodeficiency virus infection: the Hawaii aging with HIV cohort study. Cerebrovasc Dis. 2007;24(2–3):236–41.PubMedCrossRef
66.
67.
go back to reference Valcour V, Shikuma C, Shiramizu B, Williams A, Watters M, Grove JS, et al. Diabetes, insulin resistance, and dementia among HIV-1-infected patients. JAIDS. 2005;38(1):31–6.PubMedCentralPubMed Valcour V, Shikuma C, Shiramizu B, Williams A, Watters M, Grove JS, et al. Diabetes, insulin resistance, and dementia among HIV-1-infected patients. JAIDS. 2005;38(1):31–6.PubMedCentralPubMed
68.
go back to reference Braithwaite RS, Roberts MS, Chang CCH, Goetz MB, Gibert CL, Rodriguez-Barradas MC, et al. Influence of alternative thresholds for initiating HIV treatment on quality-adjusted life expectancy: a decision model. Ann Intern Med. 2008;148(3):178–85.PubMedCentralPubMedCrossRef Braithwaite RS, Roberts MS, Chang CCH, Goetz MB, Gibert CL, Rodriguez-Barradas MC, et al. Influence of alternative thresholds for initiating HIV treatment on quality-adjusted life expectancy: a decision model. Ann Intern Med. 2008;148(3):178–85.PubMedCentralPubMedCrossRef
69.
go back to reference Oursler KK, Goulet JL, Leaf DA, Akingicil A, Katzel LI, Justice A, et al. Association of comorbidity with physical disability in older HIV-infected adults. AIDS Patient Care STDs. 2006;20(11):782–91.PubMedCrossRef Oursler KK, Goulet JL, Leaf DA, Akingicil A, Katzel LI, Justice A, et al. Association of comorbidity with physical disability in older HIV-infected adults. AIDS Patient Care STDs. 2006;20(11):782–91.PubMedCrossRef
70.
go back to reference Green TC, Kershaw T, Lin H, Heimer R, Goulet JL, Kraemer KL, et al. Patterns of drug use and abuse among aging adults with and without HIV: a latent class analysis of a US Veteran cohort. Drug Alcohol Depend. 2010;110(3):208–20.PubMedCentralPubMedCrossRef Green TC, Kershaw T, Lin H, Heimer R, Goulet JL, Kraemer KL, et al. Patterns of drug use and abuse among aging adults with and without HIV: a latent class analysis of a US Veteran cohort. Drug Alcohol Depend. 2010;110(3):208–20.PubMedCentralPubMedCrossRef
71.
go back to reference Justice AC, Zingmond DS, Gordon KS, Fultz SL, Goulet JL, King Jr, et al. Drug toxicity, HIV progression, or comorbidity of aging: does tipranavir use increase the risk of intracranial hemorrhage? Clin Infect Dis. 2008;47(9):1226–30.PubMedCrossRef Justice AC, Zingmond DS, Gordon KS, Fultz SL, Goulet JL, King Jr, et al. Drug toxicity, HIV progression, or comorbidity of aging: does tipranavir use increase the risk of intracranial hemorrhage? Clin Infect Dis. 2008;47(9):1226–30.PubMedCrossRef
72.
go back to reference Zingmond DS, Kilbourne AM, Justice AC, Wenger NS, Rodriguez-Barradas M, Rabeneck L, et al. Differences in symptom expression in older HIV-positive patients: the veterans aging cohort 3 site study and HIV cost and service utilization study experience. J Acquir Immune Defic Syndr. 2003;33(Suppl. 2):S84–92.PubMedCrossRef Zingmond DS, Kilbourne AM, Justice AC, Wenger NS, Rodriguez-Barradas M, Rabeneck L, et al. Differences in symptom expression in older HIV-positive patients: the veterans aging cohort 3 site study and HIV cost and service utilization study experience. J Acquir Immune Defic Syndr. 2003;33(Suppl. 2):S84–92.PubMedCrossRef
73.
go back to reference Braithwaite RS, Goulet J, Kudel I, Tsevat J, Justice AC. Quantifying the decrement in utility from perceived side effects of combination antiretroviral therapies in patients with HIV. Value Health. 2008;11(5):975–9.PubMedCentralPubMedCrossRef Braithwaite RS, Goulet J, Kudel I, Tsevat J, Justice AC. Quantifying the decrement in utility from perceived side effects of combination antiretroviral therapies in patients with HIV. Value Health. 2008;11(5):975–9.PubMedCentralPubMedCrossRef
74.
go back to reference Goulet JL, Fultz SL, Rimland D, Butt A, Gibert C, Rodriguez-Barradas M, et al. Aging and infectious diseases: do patterns of comorbidity vary by HIV status, age, and HIV severity? Clin Infect Dis. 2007;45(12):1593–601.PubMedCentralPubMedCrossRef Goulet JL, Fultz SL, Rimland D, Butt A, Gibert C, Rodriguez-Barradas M, et al. Aging and infectious diseases: do patterns of comorbidity vary by HIV status, age, and HIV severity? Clin Infect Dis. 2007;45(12):1593–601.PubMedCentralPubMedCrossRef
75.
go back to reference Butt AA, McGinnis K, Rodriguez-Barradas MC, Crystal S, Simberkoff M, Goetz MB, et al. HIV infection and the risk of diabetes mellitus. AIDS. 2009;23(10):1227–34.PubMedCentralPubMedCrossRef Butt AA, McGinnis K, Rodriguez-Barradas MC, Crystal S, Simberkoff M, Goetz MB, et al. HIV infection and the risk of diabetes mellitus. AIDS. 2009;23(10):1227–34.PubMedCentralPubMedCrossRef
76.
go back to reference Oursler KK, Goulet JL, Crystal S, Justice AC, Crothers K, Butt AA, et al. Association of age and comorbidity with physical function in HIV-infected and uninfected patients: results from the Veterans Aging Cohort Study. AIDS Patient Care STDs. 2011;25(1):13–20.PubMedCentralPubMedCrossRef Oursler KK, Goulet JL, Crystal S, Justice AC, Crothers K, Butt AA, et al. Association of age and comorbidity with physical function in HIV-infected and uninfected patients: results from the Veterans Aging Cohort Study. AIDS Patient Care STDs. 2011;25(1):13–20.PubMedCentralPubMedCrossRef
77.
go back to reference Nokes KM, Coleman CL, Hamilton MJ, Corless IB, Sefcik E, Kirksey KM, et al. Age-related effects on symptom status and health-related quality of life in persons with HIV/AIDS. Appl Nurs Res. 2011;24(1):10–6.PubMedCrossRef Nokes KM, Coleman CL, Hamilton MJ, Corless IB, Sefcik E, Kirksey KM, et al. Age-related effects on symptom status and health-related quality of life in persons with HIV/AIDS. Appl Nurs Res. 2011;24(1):10–6.PubMedCrossRef
78.
go back to reference Worm SW, De Wit S, Weber R, Sabin CA, Reiss P, El-Sadr W, et al. Diabetes mellitus, preexisting coronary heart disease, and the risk of subsequent coronary heart disease events in patients infected with human immunodeficiency virus: the data collection on adverse events of anti-HIV drugs (D:A:D Study). Circulation. 2009;119(6):805–11.PubMedCentralPubMedCrossRef Worm SW, De Wit S, Weber R, Sabin CA, Reiss P, El-Sadr W, et al. Diabetes mellitus, preexisting coronary heart disease, and the risk of subsequent coronary heart disease events in patients infected with human immunodeficiency virus: the data collection on adverse events of anti-HIV drugs (D:A:D Study). Circulation. 2009;119(6):805–11.PubMedCentralPubMedCrossRef
79.
go back to reference Sabin C. Response to combination antiretroviral therapy: variation by age. AIDS. 2008;22(12):1463–73. Sabin C. Response to combination antiretroviral therapy: variation by age. AIDS. 2008;22(12):1463–73.
80.
go back to reference Carr A, Grund B, Neuhaus J, El-Sadr WM, Grandits G, Gibert C, et al. Asymptomatic myocardial ischaemia in HIV-infected adults. AIDS. 2008;22(2):237–47.CrossRef Carr A, Grund B, Neuhaus J, El-Sadr WM, Grandits G, Gibert C, et al. Asymptomatic myocardial ischaemia in HIV-infected adults. AIDS. 2008;22(2):237–47.CrossRef
81.
go back to reference Popay J, Rogers A, Williams G. Rationale and standards for the systematic review of qualitative literature in health services research. Qual Health Res. 1998;8(3):341–51.PubMedCrossRef Popay J, Rogers A, Williams G. Rationale and standards for the systematic review of qualitative literature in health services research. Qual Health Res. 1998;8(3):341–51.PubMedCrossRef
82.
go back to reference Grypdonck MHF. Qualitative health research in the era of evidence-based practice. Qual Health Res. 2006;16(10):1371–85.PubMedCrossRef Grypdonck MHF. Qualitative health research in the era of evidence-based practice. Qual Health Res. 2006;16(10):1371–85.PubMedCrossRef
83.
go back to reference Malterud K. The art and science of clinical knowledge: evidence beyond measures and numbers. The Lancet. 2001;358(9279):397–400.CrossRef Malterud K. The art and science of clinical knowledge: evidence beyond measures and numbers. The Lancet. 2001;358(9279):397–400.CrossRef
84.
go back to reference Barbour RS. The case for combining qualitative and quantitative approaches in health services research. J Health Serv Res Policy. 1999;4(1):39–43.PubMed Barbour RS. The case for combining qualitative and quantitative approaches in health services research. J Health Serv Res Policy. 1999;4(1):39–43.PubMed
85.
go back to reference Murray J, Adam BD. Aging, sexuality, and HIV issues among older gay men. Can J Hum Sex. 2001;10(3–4):75–90. Murray J, Adam BD. Aging, sexuality, and HIV issues among older gay men. Can J Hum Sex. 2001;10(3–4):75–90.
86.
go back to reference Lichtenstein B. Stigma as a barrier to treatment of sexually transmitted infection in the American deep south: issues of race, gender and poverty. Soc Sci Med. 2003;57(12):2435–45.PubMedCrossRef Lichtenstein B. Stigma as a barrier to treatment of sexually transmitted infection in the American deep south: issues of race, gender and poverty. Soc Sci Med. 2003;57(12):2435–45.PubMedCrossRef
87.
go back to reference Gott M, Hinchliff S. How important is sex in later life? The views of older people. Soc Sci Med. 2003;56(8):1617–28.PubMedCrossRef Gott M, Hinchliff S. How important is sex in later life? The views of older people. Soc Sci Med. 2003;56(8):1617–28.PubMedCrossRef
88.
go back to reference Heckman T, Sikkema K, Hansen N, Kochman A, Heh V. A randomized clinical trial evaluating a coping improvement group intervention for HIV-infected older adults. J Behav Med. 2009;34(Suppl 1):102–11. Heckman T, Sikkema K, Hansen N, Kochman A, Heh V. A randomized clinical trial evaluating a coping improvement group intervention for HIV-infected older adults. J Behav Med. 2009;34(Suppl 1):102–11.
89.
go back to reference Heckman TG, Barcikowski R, Ogles B, Suhr J, Carlson B, Holroyd K, et al. A telephone-delivered coping improvement group intervention for middle-aged and older adults living with HIV/AIDS. Ann Behav Med. 2006;32(1):27–38.PubMedCrossRef Heckman TG, Barcikowski R, Ogles B, Suhr J, Carlson B, Holroyd K, et al. A telephone-delivered coping improvement group intervention for middle-aged and older adults living with HIV/AIDS. Ann Behav Med. 2006;32(1):27–38.PubMedCrossRef
90.
go back to reference Heckman TG, Kochman A, Sikkema KJ, Kalichman SC, Masten J, Bergholte J, et al. Pilot coping improvement intervention for late middle-aged and older adults living with HIV/AIDS in the USA. AIDS Care. 2001;13(1):129–39.PubMedCrossRef Heckman TG, Kochman A, Sikkema KJ, Kalichman SC, Masten J, Bergholte J, et al. Pilot coping improvement intervention for late middle-aged and older adults living with HIV/AIDS in the USA. AIDS Care. 2001;13(1):129–39.PubMedCrossRef
91.
go back to reference Neundorfer MM, Camp CJ, Lee MM, Skrajner MJ, Malone ML, Carr JR. Compensating for cognitive deficits in persons aged 50 and over with HIV/AIDS: a pilot study of a cognitive intervention. J HIV/AIDS Soc Serv. 2004;3(1):79–97.CrossRef Neundorfer MM, Camp CJ, Lee MM, Skrajner MJ, Malone ML, Carr JR. Compensating for cognitive deficits in persons aged 50 and over with HIV/AIDS: a pilot study of a cognitive intervention. J HIV/AIDS Soc Serv. 2004;3(1):79–97.CrossRef
92.
go back to reference Vance DE, Burrage J, Couch A Jr, Raper J. Promoting successful aging with HIV through hardiness: implications for nursing practice and research. J Gerontol Nurs. 2008;34(6):22–9.PubMedCrossRef Vance DE, Burrage J, Couch A Jr, Raper J. Promoting successful aging with HIV through hardiness: implications for nursing practice and research. J Gerontol Nurs. 2008;34(6):22–9.PubMedCrossRef
93.
go back to reference Jimenez AD. Triple jeopardy: targeting older men of color who have sex with men. J Acquir Immune Defic Syndr. 2003;33(Suppl 2):S222–5.PubMedCrossRef Jimenez AD. Triple jeopardy: targeting older men of color who have sex with men. J Acquir Immune Defic Syndr. 2003;33(Suppl 2):S222–5.PubMedCrossRef
94.
go back to reference Jacobs RJ, Thomlison B. Self-silencing and age as risk factors for sexually acquired HIV in midlife and older women. J Aging Health. 2009;21(1):102–28.PubMedCrossRef Jacobs RJ, Thomlison B. Self-silencing and age as risk factors for sexually acquired HIV in midlife and older women. J Aging Health. 2009;21(1):102–28.PubMedCrossRef
95.
go back to reference Appay V, Sauce D. Immune activation and inflammation in HIV-1 infection: causes and consequences. J Pathol. 2008;214(2):231–41.PubMedCrossRef Appay V, Sauce D. Immune activation and inflammation in HIV-1 infection: causes and consequences. J Pathol. 2008;214(2):231–41.PubMedCrossRef
96.
go back to reference Gandhi RT, Sax PE, Grinspoon SK. Metabolic and cardiovascular complications in HIV-infected patients: new challenges for a new age. J Infect Dis. 2012;205(suppl 3):S353–4.PubMedCentralPubMedCrossRef Gandhi RT, Sax PE, Grinspoon SK. Metabolic and cardiovascular complications in HIV-infected patients: new challenges for a new age. J Infect Dis. 2012;205(suppl 3):S353–4.PubMedCentralPubMedCrossRef
97.
98.
go back to reference Pineda JA, Alcamí J, Blanco JR, Blanco J, Boix V, Casado JL, et al. Hot immunological topics in HIV infection. J AIDS Clin Res. 2011;2(118):2. Pineda JA, Alcamí J, Blanco JR, Blanco J, Boix V, Casado JL, et al. Hot immunological topics in HIV infection. J AIDS Clin Res. 2011;2(118):2.
99.
go back to reference Ances BM, Ortega M, Vaida F, Heaps J, Paul R. Independent effects of HIV, aging, and HAART on brain volumetric measures. JAIDS. 2012;59(5):469–77.PubMedCentralPubMed Ances BM, Ortega M, Vaida F, Heaps J, Paul R. Independent effects of HIV, aging, and HAART on brain volumetric measures. JAIDS. 2012;59(5):469–77.PubMedCentralPubMed
100.
go back to reference Guaraldi G, Orlando G, Zona S, Menozzi M, Carli F, Garlassi E, et al. Premature age-related comorbidities among HIV-infected persons compared with the general population. Clin Infect Dis. 2011;53(11):1120–6.PubMedCrossRef Guaraldi G, Orlando G, Zona S, Menozzi M, Carli F, Garlassi E, et al. Premature age-related comorbidities among HIV-infected persons compared with the general population. Clin Infect Dis. 2011;53(11):1120–6.PubMedCrossRef
102.
go back to reference World Health Organization. Preamble to the Constitution of the World Health Organization as adopted by the International Health Conference, New York, 19-22 June, 1946; signed on 22 July 1946 by the representatives of 61 States (Official Records of the World Health Organization, no. 2, p. 100) and entered into force on 7 April 1948. World Health Organization. Preamble to the Constitution of the World Health Organization as adopted by the International Health Conference, New York, 19-22 June, 1946; signed on 22 July 1946 by the representatives of 61 States (Official Records of the World Health Organization, no. 2, p. 100) and entered into force on 7 April 1948.
Metadata
Title
Evidence Informing the Intersection of HIV, Aging and Health: A Scoping Review
Authors
Lori A. Chambers
Michael G. Wilson
Sergio Rueda
David Gogolishvili
Maggie Qiyun Shi
Sean B. Rourke
The Positive Aging Review Team
Publication date
01-04-2014
Publisher
Springer US
Published in
AIDS and Behavior / Issue 4/2014
Print ISSN: 1090-7165
Electronic ISSN: 1573-3254
DOI
https://doi.org/10.1007/s10461-013-0627-5

Other articles of this Issue 4/2014

AIDS and Behavior 4/2014 Go to the issue
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discuss last year's major advances in heart failure and cardiomyopathies.