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Published in: AIDS and Behavior 4/2014

01-04-2014 | Original Paper

Effectiveness of Mindfulness-Based Cognitive Therapy on the Quality of Life, Emotional Status, and CD4 Cell Count of Patients Aging with HIV Infection

Authors: Marian Gonzalez-Garcia, Maria Jose Ferrer, Xavier Borras, Jose A. Muñoz-Moreno, Cristina Miranda, Jordi Puig, Nuria Perez-Alvarez, Joaquim Soler, Albert Feliu-Soler, Bonaventura Clotet, Carmina R. Fumaz

Published in: AIDS and Behavior | Issue 4/2014

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Abstract

Long-term diagnosed and treated HIV-infected patients have to cope with a wide range of challenges that threaten their ability to age successfully. We report the results of a randomized controlled trial testing the effects of a mindfulness-based cognitive therapy (MBCT) program on quality of life (QoL), emotional status, and immune status over a 3-month period. Forty HIV-infected patients diagnosed prior to 1996 and on cART for a minimum of 5 years were randomized to follow an MBCT program (n = 20) or remain as controls (routine follow-up) (n = 20). A regression analysis was performed, and the measurement of effect size was estimated using Cohen’s d. QoL, psychological stress, depressive symptoms, and anxiety symptoms improved in the MBCT group compared with the control group. During follow-up, patients in the MBCT group had a significantly increased CD4 cell count. Effect sizes for MBCT on the variables assessed were large (d = 0.8). The findings suggest that this program may help to promote successful aging in these patients.
Literature
1.
go back to reference Mrus JM, Leonard AC, Yi MS, et al. Health-related quality of life in veterans and non-veterans with HIV/AIDS. J Gen Intern Med. 2006;21(Suppl 5):S39–47.PubMedCentralPubMedCrossRef Mrus JM, Leonard AC, Yi MS, et al. Health-related quality of life in veterans and non-veterans with HIV/AIDS. J Gen Intern Med. 2006;21(Suppl 5):S39–47.PubMedCentralPubMedCrossRef
2.
go back to reference Lohse N, Hansen AB, Pedersen G, et al. Survival of persons with and without HIV infection in Denmark, 1995–2005. Ann Intern Med. 2007;146(2):87–95.PubMedCrossRef Lohse N, Hansen AB, Pedersen G, et al. Survival of persons with and without HIV infection in Denmark, 1995–2005. Ann Intern Med. 2007;146(2):87–95.PubMedCrossRef
3.
go back to reference Antiretroviral Therapy Cohort Collaboration. Life expectancy of individuals on combination antiretroviral therapy in high-income countries: a collaborative analysis of 14 cohort studies. Lancet. 2008;372(9635):293–9.CrossRef Antiretroviral Therapy Cohort Collaboration. Life expectancy of individuals on combination antiretroviral therapy in high-income countries: a collaborative analysis of 14 cohort studies. Lancet. 2008;372(9635):293–9.CrossRef
4.
go back to reference May M, Gompels M, Delpech V, et al. Impact of late diagnosis and treatment on life-expectancy in people with HIV-1: UK Collaborative HIV Cohort (UK CHIC) Study. BMJ. 2011;343:d6016.PubMedCentralPubMedCrossRef May M, Gompels M, Delpech V, et al. Impact of late diagnosis and treatment on life-expectancy in people with HIV-1: UK Collaborative HIV Cohort (UK CHIC) Study. BMJ. 2011;343:d6016.PubMedCentralPubMedCrossRef
5.
go back to reference Effros RB, Fletcher CV, Gebo K, et al. Aging and infectious diseases: workshop on HIV infection and aging: what is known and future research directions. Clin Infect Dis. 2008;47(4):542–53.PubMedCentralPubMedCrossRef Effros RB, Fletcher CV, Gebo K, et al. Aging and infectious diseases: workshop on HIV infection and aging: what is known and future research directions. Clin Infect Dis. 2008;47(4):542–53.PubMedCentralPubMedCrossRef
7.
go back to reference Bhatia R, Ryscavage P, Taiwo B. Accelerated aging and human immunodeficiency virus infection: emerging challenges of growing older in the era of successful antiretroviral therapy. J Neurovirol. 2012;18(4):247–55.PubMedCrossRef Bhatia R, Ryscavage P, Taiwo B. Accelerated aging and human immunodeficiency virus infection: emerging challenges of growing older in the era of successful antiretroviral therapy. J Neurovirol. 2012;18(4):247–55.PubMedCrossRef
8.
go back to reference Guaraldi G, Orlando G, Zona S, et al. Premature age-related comorbidities among HIV-infected persons compared with the general population. Clin Infect Dis. 2011;53(11):1120–6.PubMedCrossRef Guaraldi G, Orlando G, Zona S, et al. Premature age-related comorbidities among HIV-infected persons compared with the general population. Clin Infect Dis. 2011;53(11):1120–6.PubMedCrossRef
9.
go back to reference Capeau J. Premature aging and premature age-related comorbidities in HIV-infected patients: facts and hypotheses. Clin Infect Dis. 2011;53(11):1127–9.PubMedCrossRef Capeau J. Premature aging and premature age-related comorbidities in HIV-infected patients: facts and hypotheses. Clin Infect Dis. 2011;53(11):1127–9.PubMedCrossRef
10.
11.
go back to reference Bing EG, Hays RD, Jacobson LP, et al. Health-related quality of life among people with HIV disease: results from the Multicenter AIDS Cohort Study. Qual Life Res. 2000;9(1):55–63.PubMedCrossRef Bing EG, Hays RD, Jacobson LP, et al. Health-related quality of life among people with HIV disease: results from the Multicenter AIDS Cohort Study. Qual Life Res. 2000;9(1):55–63.PubMedCrossRef
12.
go back to reference Davis S. Clinical sequelae affecting quality of life in the HIV-infected patient. J Assoc Nurses AIDS Care. 2004;15(Suppl 5):28S–33S.PubMedCrossRef Davis S. Clinical sequelae affecting quality of life in the HIV-infected patient. J Assoc Nurses AIDS Care. 2004;15(Suppl 5):28S–33S.PubMedCrossRef
13.
go back to reference Silverman GK, Jacobs SC, Kasl SV, et al. Quality of life impairments associated with diagnostic criteria for traumatic grief. Psychol Med. 2000;30(4):857–62.PubMedCrossRef Silverman GK, Jacobs SC, Kasl SV, et al. Quality of life impairments associated with diagnostic criteria for traumatic grief. Psychol Med. 2000;30(4):857–62.PubMedCrossRef
14.
go back to reference Liu C, Johnson L, Ostrow D, Silvestre A, Vusscher B, Jacobson LP. Predictors for lower quality of life in the HAART era among HIV-infected men. J Acquir Immune Defic Syndr. 2006;42(4):470–7.PubMedCrossRef Liu C, Johnson L, Ostrow D, Silvestre A, Vusscher B, Jacobson LP. Predictors for lower quality of life in the HAART era among HIV-infected men. J Acquir Immune Defic Syndr. 2006;42(4):470–7.PubMedCrossRef
15.
go back to reference Burgess AP, Carretero M, Elkington A, Pasqual-Marsettin E, Lobaccaro C, Catalán J. The role of personality, coping style and social support in health-related quality of life in HIV infection. Qual Life Res. 2000;9(4):423–37.PubMedCrossRef Burgess AP, Carretero M, Elkington A, Pasqual-Marsettin E, Lobaccaro C, Catalán J. The role of personality, coping style and social support in health-related quality of life in HIV infection. Qual Life Res. 2000;9(4):423–37.PubMedCrossRef
16.
go back to reference Vance DE, Struzick T, Childs G. Challenges of depression and suicidal ideation associated with aging with HIV/AIDS: implications for social work. J Gerontol Soc Work. 2010;53(2):159–75.PubMedCrossRef Vance DE, Struzick T, Childs G. Challenges of depression and suicidal ideation associated with aging with HIV/AIDS: implications for social work. J Gerontol Soc Work. 2010;53(2):159–75.PubMedCrossRef
17.
go back to reference Owen G, Catalan J. ‘We never expected this to happen’: narratives of ageing with HIV among gay men living in London, UK. Cult Health Sex. 2012;14(1):59–72.PubMedCrossRef Owen G, Catalan J. ‘We never expected this to happen’: narratives of ageing with HIV among gay men living in London, UK. Cult Health Sex. 2012;14(1):59–72.PubMedCrossRef
18.
go back to reference Fumaz CR, Muñoz-Moreno JA, Ferrer MJ, et al. Emotional impact of premature aging symptoms in long-term treated HIV-infected subjects. J Acquir Immune Defic Syndr. 2012;59(1):e5–8.PubMedCrossRef Fumaz CR, Muñoz-Moreno JA, Ferrer MJ, et al. Emotional impact of premature aging symptoms in long-term treated HIV-infected subjects. J Acquir Immune Defic Syndr. 2012;59(1):e5–8.PubMedCrossRef
19.
go back to reference Irwin MR. Human psychoneuroimmunology: 20 years of discovery. Brain Behav Immun. 2008;22(2):129–39.PubMedCrossRef Irwin MR. Human psychoneuroimmunology: 20 years of discovery. Brain Behav Immun. 2008;22(2):129–39.PubMedCrossRef
20.
go back to reference Leserman J. Role of depression, stress, and trauma in HIV disease progression. Psychosom Med. 2008;70(5):539–45.PubMedCrossRef Leserman J. Role of depression, stress, and trauma in HIV disease progression. Psychosom Med. 2008;70(5):539–45.PubMedCrossRef
21.
go back to reference Bottonari KA, Safren SA, McQuaid JR, Hsiao C-B, Roberts JE. A longitudinal investigation of the impact of life stress on HIV treatment adherence. J Behav Med. 2010;33(6):486–95.PubMedCentralPubMedCrossRef Bottonari KA, Safren SA, McQuaid JR, Hsiao C-B, Roberts JE. A longitudinal investigation of the impact of life stress on HIV treatment adherence. J Behav Med. 2010;33(6):486–95.PubMedCentralPubMedCrossRef
22.
go back to reference Campos LN, Guimaraes MD, Remien RH. Anxiety and depression symptoms as risk factors for non-adherence to antiretroviral therapy in Brazil. AIDS Behav. 2010;14(2):289–99.PubMedCentralPubMedCrossRef Campos LN, Guimaraes MD, Remien RH. Anxiety and depression symptoms as risk factors for non-adherence to antiretroviral therapy in Brazil. AIDS Behav. 2010;14(2):289–99.PubMedCentralPubMedCrossRef
23.
go back to reference Kacanek D, Jacobson DL, Spiegelman D, Wanke C, Isaac R, Wilson IB. Incident depression symptoms are associated with poorer HAART adherence: a longitudinal analysis from the nutrition for healthy living study. J Acquir Immune Defic Syndr. 2010;53(2):266–72.PubMedCentralPubMedCrossRef Kacanek D, Jacobson DL, Spiegelman D, Wanke C, Isaac R, Wilson IB. Incident depression symptoms are associated with poorer HAART adherence: a longitudinal analysis from the nutrition for healthy living study. J Acquir Immune Defic Syndr. 2010;53(2):266–72.PubMedCentralPubMedCrossRef
24.
go back to reference Logsdon-Conradsen S. Using mindfulness meditation to promote holistic health in individuals with HIV/AIDS. Cogn Behav Pract. 2002;9(1):67–72.CrossRef Logsdon-Conradsen S. Using mindfulness meditation to promote holistic health in individuals with HIV/AIDS. Cogn Behav Pract. 2002;9(1):67–72.CrossRef
25.
go back to reference High KP, Brennan-Ing M, Clifford DB, et al. HIV and aging: state of knowledge and areas of critical need for research. A report to the NIH Office of AIDS Research by the HIV and Aging Working Group. J Acquir Immune Defic Syndr. 2012;60(Suppl 1):S1–18.PubMedCrossRef High KP, Brennan-Ing M, Clifford DB, et al. HIV and aging: state of knowledge and areas of critical need for research. A report to the NIH Office of AIDS Research by the HIV and Aging Working Group. J Acquir Immune Defic Syndr. 2012;60(Suppl 1):S1–18.PubMedCrossRef
26.
go back to reference Carlson LE. Mindfulness-based interventions for physical conditions: a narrative review evaluating levels of evidence. ISRN Psychiatry. 2012;2012:651583.PubMedCentralPubMedCrossRef Carlson LE. Mindfulness-based interventions for physical conditions: a narrative review evaluating levels of evidence. ISRN Psychiatry. 2012;2012:651583.PubMedCentralPubMedCrossRef
27.
go back to reference Segal ZV, Williams JMG, Teasdale JD. Mindfulness-based cognitive therapy for depression: a new approach to preventing relapse. New York: Guilford Press; 2002. Segal ZV, Williams JMG, Teasdale JD. Mindfulness-based cognitive therapy for depression: a new approach to preventing relapse. New York: Guilford Press; 2002.
28.
go back to reference Kabat-Zinn J. Full catastrophe living: using the wisdom of your body and mind to face stress, pain, and illness. New York: Delta; 1990. Kabat-Zinn J. Full catastrophe living: using the wisdom of your body and mind to face stress, pain, and illness. New York: Delta; 1990.
29.
go back to reference Beck AT, Rush AJ, Shaw BF, Emery G. Cognitive therapy of depression. New York: Guilford Press; 1979. Beck AT, Rush AJ, Shaw BF, Emery G. Cognitive therapy of depression. New York: Guilford Press; 1979.
30.
go back to reference Foley E, Baillie A, Huxter M, Price M, Sinclair E. Mindfulness-based cognitive therapy for individuals whose lives have been affected by cancer: a randomized controlled trial. J Consult Clin Psychol. 2010;78(1):72–9.PubMedCrossRef Foley E, Baillie A, Huxter M, Price M, Sinclair E. Mindfulness-based cognitive therapy for individuals whose lives have been affected by cancer: a randomized controlled trial. J Consult Clin Psychol. 2010;78(1):72–9.PubMedCrossRef
31.
go back to reference Moustgaard AK. Mindfulness-based cognitive therapy (MBCT) for stroke survivors: an application of a novel intervention. Doctoral dissertation, Lakehead University, Canada; 2005. Moustgaard AK. Mindfulness-based cognitive therapy (MBCT) for stroke survivors: an application of a novel intervention. Doctoral dissertation, Lakehead University, Canada; 2005.
32.
go back to reference Sibinga EM, Stewart M, Magyari T, Welsh CK, Hutton N, Ellen JM. Mindfulness-based stress reduction for HIV-infected youth: a pilot study. Explore (NY). 2008;4(1):36–7.PubMedCrossRef Sibinga EM, Stewart M, Magyari T, Welsh CK, Hutton N, Ellen JM. Mindfulness-based stress reduction for HIV-infected youth: a pilot study. Explore (NY). 2008;4(1):36–7.PubMedCrossRef
33.
go back to reference Duncan LG, Moskowitz JT, Neilands TB, Dilworth SE, Hecht FM, Johnson MO. Mindfulness-based stress reduction for HIV treatment side effects: a randomized, wait-list controlled trial. J Pain Symptom Manage. 2012;43(2):161–71.PubMedCentralPubMedCrossRef Duncan LG, Moskowitz JT, Neilands TB, Dilworth SE, Hecht FM, Johnson MO. Mindfulness-based stress reduction for HIV treatment side effects: a randomized, wait-list controlled trial. J Pain Symptom Manage. 2012;43(2):161–71.PubMedCentralPubMedCrossRef
34.
go back to reference Gayner B, Esplen MJ, Deroche P, et al. A randomized controlled trial of mindfulness-based stress reduction to manage affective symptoms and improve quality of life in gay men living with HIV. J Behav Med. 2012;35(3):272–85.PubMedCrossRef Gayner B, Esplen MJ, Deroche P, et al. A randomized controlled trial of mindfulness-based stress reduction to manage affective symptoms and improve quality of life in gay men living with HIV. J Behav Med. 2012;35(3):272–85.PubMedCrossRef
35.
go back to reference Robinson FP, Mathews HL, Witek-Janusez L. Psycho-endocrine-immune response to mindfulness-based stress reduction in individuals infected with the human immunodeficiency virus: a quasiexperimental study. J Altern Complement Med. 2003;9(5):683–94.PubMedCrossRef Robinson FP, Mathews HL, Witek-Janusez L. Psycho-endocrine-immune response to mindfulness-based stress reduction in individuals infected with the human immunodeficiency virus: a quasiexperimental study. J Altern Complement Med. 2003;9(5):683–94.PubMedCrossRef
36.
go back to reference Creswell JD, Myers HF, Cole SW, Irwin MR. Mindfulness meditation training effects on CD4+ T lymphocytes in HIV-1 infected adults: a small randomized controlled trial. Brain Behav Immun. 2009;23(2):184–8.PubMedCentralPubMedCrossRef Creswell JD, Myers HF, Cole SW, Irwin MR. Mindfulness meditation training effects on CD4+ T lymphocytes in HIV-1 infected adults: a small randomized controlled trial. Brain Behav Immun. 2009;23(2):184–8.PubMedCentralPubMedCrossRef
37.
go back to reference Jam S, Imani AH, Foroughi M, SeyedAlinaghi S, Koochak HE, Mohraz M. The effects of mindfulness-based stress reduction (MBSR) program in Iranian HIV/AIDS patients: a pilot study. Acta Med Iran. 2010;48(2):101–6.PubMed Jam S, Imani AH, Foroughi M, SeyedAlinaghi S, Koochak HE, Mohraz M. The effects of mindfulness-based stress reduction (MBSR) program in Iranian HIV/AIDS patients: a pilot study. Acta Med Iran. 2010;48(2):101–6.PubMed
38.
go back to reference SeyedAlinaghi S, Jam S, Foroughi M, et al. Randomized controlled trial of mindfulness-based stress reduction delivered to human immunodeficiency virus-positive patients in Iran: effects on CD4+ T lymphocyte count and medical and psychological symptoms. Psychosom Med. 2012;74(6):620–7.PubMedCentralPubMedCrossRef SeyedAlinaghi S, Jam S, Foroughi M, et al. Randomized controlled trial of mindfulness-based stress reduction delivered to human immunodeficiency virus-positive patients in Iran: effects on CD4+ T lymphocyte count and medical and psychological symptoms. Psychosom Med. 2012;74(6):620–7.PubMedCentralPubMedCrossRef
39.
go back to reference Weston E, Moran P, Acree M, et al. Effect of MBSR and psychological state on inflammatory markers in HIV positive adults. BMC Complement Altern Med. 2012;12(Suppl 1):O6.PubMedCentralCrossRef Weston E, Moran P, Acree M, et al. Effect of MBSR and psychological state on inflammatory markers in HIV positive adults. BMC Complement Altern Med. 2012;12(Suppl 1):O6.PubMedCentralCrossRef
40.
go back to reference Wood NA. Mindfulness-based cognitive therapy for the symptoms of depression in a community-based HIV/AIDS Clinic: outcomes and feasibility. Chester: Widener University; 2008. Wood NA. Mindfulness-based cognitive therapy for the symptoms of depression in a community-based HIV/AIDS Clinic: outcomes and feasibility. Chester: Widener University; 2008.
41.
go back to reference Teasdale JD, Segal ZV, Williams JMG, Ridgeway VA, Soulsby JM, Lau MA. Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. J Consult Clin Psychol. 2000;68(4):615–23.PubMedCrossRef Teasdale JD, Segal ZV, Williams JMG, Ridgeway VA, Soulsby JM, Lau MA. Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. J Consult Clin Psychol. 2000;68(4):615–23.PubMedCrossRef
42.
go back to reference Tuldrà A, Fumaz CR, Ferrer MJ, et al. Prospective randomized two-arm controlled study to determine the efficacy of a specific intervention to improve long-term adherence to highly active antiretroviral therapy. J Acquir Inmune Defic Syndr. 2000;25(3):221–8.CrossRef Tuldrà A, Fumaz CR, Ferrer MJ, et al. Prospective randomized two-arm controlled study to determine the efficacy of a specific intervention to improve long-term adherence to highly active antiretroviral therapy. J Acquir Inmune Defic Syndr. 2000;25(3):221–8.CrossRef
43.
go back to reference Fumaz CR, Muñoz-Moreno JA, Moltó J, et al. Sustained antiretroviral treatment adherence in survivors of the pre-HAART era: attitudes and beliefs. AIDS Care. 2008;20(7):796–805.PubMedCrossRef Fumaz CR, Muñoz-Moreno JA, Moltó J, et al. Sustained antiretroviral treatment adherence in survivors of the pre-HAART era: attitudes and beliefs. AIDS Care. 2008;20(7):796–805.PubMedCrossRef
44.
go back to reference Paterson DL, Swindells S, Mohr J, et al. Adherence to protease inhibitor therapy and outcomes in patients with HIV infection. Ann Intern Med. 2000;133(1):21–30.PubMedCrossRef Paterson DL, Swindells S, Mohr J, et al. Adherence to protease inhibitor therapy and outcomes in patients with HIV infection. Ann Intern Med. 2000;133(1):21–30.PubMedCrossRef
45.
go back to reference Hendricks K, Tang A, Spiegelman D, Skinner S, Woods M. Dietary intake in human immunodeficiency virus-infected adults: a comparison of dietary assessment methods. J Am Diet Assoc. 2005;105(4):532–40.PubMedCrossRef Hendricks K, Tang A, Spiegelman D, Skinner S, Woods M. Dietary intake in human immunodeficiency virus-infected adults: a comparison of dietary assessment methods. J Am Diet Assoc. 2005;105(4):532–40.PubMedCrossRef
46.
go back to reference Mitrou PN, Kipnis V, Thiébaut AC, et al. Mediterranean dietary pattern and prediction of all-cause mortality in a US population: results from the NIH-AARP Diet and Health Study. Arch Intern Med. 2007;167(22):2461–8.PubMedCrossRef Mitrou PN, Kipnis V, Thiébaut AC, et al. Mediterranean dietary pattern and prediction of all-cause mortality in a US population: results from the NIH-AARP Diet and Health Study. Arch Intern Med. 2007;167(22):2461–8.PubMedCrossRef
47.
go back to reference Wilson PW, D’Agostino RB, Levy D, Belanger AM, Silbershatz H, Kannel WB. Prediction of coronary heart disease using risk factor categories. Circulation. 1998;97(18):1837–47.PubMedCrossRef Wilson PW, D’Agostino RB, Levy D, Belanger AM, Silbershatz H, Kannel WB. Prediction of coronary heart disease using risk factor categories. Circulation. 1998;97(18):1837–47.PubMedCrossRef
48.
go back to reference Hunt SM, McKenna SP, McEwen J, Williams J, Papp E. The Nottingham Health Profile: subjective health status and medical consultations. Soc Sci Med A. 1981;15(3 Pt 1):221–9.PubMed Hunt SM, McKenna SP, McEwen J, Williams J, Papp E. The Nottingham Health Profile: subjective health status and medical consultations. Soc Sci Med A. 1981;15(3 Pt 1):221–9.PubMed
49.
go back to reference Alonso J, Anto JM, Moreno C. Spanish version of the Nottingham Health Profile: translation and preliminary validity. Am J Public Health. 1990;80(6):704–8.PubMedCentralPubMedCrossRef Alonso J, Anto JM, Moreno C. Spanish version of the Nottingham Health Profile: translation and preliminary validity. Am J Public Health. 1990;80(6):704–8.PubMedCentralPubMedCrossRef
50.
go back to reference Alonso J, Prieto L, Antó JM. The Spanish version of the Nottingham Health Profile: a review of adaptation and instrument characteristics. Qual Life Res. 1994;3(6):385–93.PubMedCrossRef Alonso J, Prieto L, Antó JM. The Spanish version of the Nottingham Health Profile: a review of adaptation and instrument characteristics. Qual Life Res. 1994;3(6):385–93.PubMedCrossRef
51.
go back to reference Badia X, Alonso J, Brosa M, Lock P. Reliability of the Spanish version of the Nottingham Health Profile in patients with stable end-stage renal disease. Soc Sci Med. 1994;38(1):153–8.PubMedCrossRef Badia X, Alonso J, Brosa M, Lock P. Reliability of the Spanish version of the Nottingham Health Profile in patients with stable end-stage renal disease. Soc Sci Med. 1994;38(1):153–8.PubMedCrossRef
52.
go back to reference Permanyer-Miralda G, Alonso J, Antó JM, Alijarde-Guimerá M, Soler–Soler J. Comparison of perceived health status and conventional functional evaluation in stable patients with coronary artery disease. J Clin Epidemiol. 1991;44(8):779–86.PubMedCrossRef Permanyer-Miralda G, Alonso J, Antó JM, Alijarde-Guimerá M, Soler–Soler J. Comparison of perceived health status and conventional functional evaluation in stable patients with coronary artery disease. J Clin Epidemiol. 1991;44(8):779–86.PubMedCrossRef
53.
go back to reference Cohen S, Williamson G. Perceived stress in a probability sample of the United States. In: Spacapan S, Oskamp S, editors. The social psychology of health: Claremont symposium on applied social psychology. Newbury Park: Sage; 1988. p. 31–67. Cohen S, Williamson G. Perceived stress in a probability sample of the United States. In: Spacapan S, Oskamp S, editors. The social psychology of health: Claremont symposium on applied social psychology. Newbury Park: Sage; 1988. p. 31–67.
54.
go back to reference Remor E. Psychometric properties of a European Spanish version of the Perceived Stress Scale (PSS). Span J Psychol. 2006;9(1):86–93.PubMed Remor E. Psychometric properties of a European Spanish version of the Perceived Stress Scale (PSS). Span J Psychol. 2006;9(1):86–93.PubMed
55.
go back to reference Beck AT, Steer R, Brown GK. BDI-II: Beck Depression Inventory. 2nd ed. San Antonio: The Psychological Corporation; 1996. Beck AT, Steer R, Brown GK. BDI-II: Beck Depression Inventory. 2nd ed. San Antonio: The Psychological Corporation; 1996.
56.
go back to reference Sanz J, García MP, Espinosa R, et al. Adaptación española del Inventario para la Depresión de Beck-II (BDI-II): 3. Propiedades psicométricas en pacientes con trastornos psicológicos. Clínica y Salud. 2005;16(2):121–42. Sanz J, García MP, Espinosa R, et al. Adaptación española del Inventario para la Depresión de Beck-II (BDI-II): 3. Propiedades psicométricas en pacientes con trastornos psicológicos. Clínica y Salud. 2005;16(2):121–42.
57.
go back to reference Beck AT, Brown G, Epstein N, et al. An inventory for measuring clinical anxiety: psychometric properties. J Consult Clin Psychol. 1988;56(6):893–7.PubMedCrossRef Beck AT, Brown G, Epstein N, et al. An inventory for measuring clinical anxiety: psychometric properties. J Consult Clin Psychol. 1988;56(6):893–7.PubMedCrossRef
58.
go back to reference Sanz J, Navarro ME. Propiedades psicométricas de una versión española del Inventario de Ansiedad de Beck (BAI) en estudiantes universitarios. Ansiedad y Estrés. 2003;9(1):59–84. Sanz J, Navarro ME. Propiedades psicométricas de una versión española del Inventario de Ansiedad de Beck (BAI) en estudiantes universitarios. Ansiedad y Estrés. 2003;9(1):59–84.
59.
go back to reference Sanz J, Garcia-Vera MP, Fortun M. El “inventario de ansiedad de beck” (BAI): propiedades psicométricas de la versión española en pacientes con trastornos psicológicos. The Free Library (2012, September 1). http://www.thefreelibrary.com/El “inventario de ansiedad de beck” (BAI): propiedades psicometricas…-a0314254361. Accessed 2 July 2013. Sanz J, Garcia-Vera MP, Fortun M. El “inventario de ansiedad de beck” (BAI): propiedades psicométricas de la versión española en pacientes con trastornos psicológicos. The Free Library (2012, September 1). http://​www.​thefreelibrary.​com/​El “inventario de ansiedad de beck” (BAI): propiedades psicometricas…-a0314254361. Accessed 2 July 2013.
60.
go back to reference Cohen J. Statistical power analysis for the behavioral sciences. 2nd ed. Hillsdale: Lawrence Erlbaum Associates; 1988. Cohen J. Statistical power analysis for the behavioral sciences. 2nd ed. Hillsdale: Lawrence Erlbaum Associates; 1988.
61.
go back to reference Casado JM, González N, Moraleda S, Orueta R, Carmona J, Gomez-Calcerrada RM. Calidad de vida relacionada con la salud en pacientes ancianos en atención primaria. Atención Primaria. 2001;28(3):167–73.PubMedCrossRef Casado JM, González N, Moraleda S, Orueta R, Carmona J, Gomez-Calcerrada RM. Calidad de vida relacionada con la salud en pacientes ancianos en atención primaria. Atención Primaria. 2001;28(3):167–73.PubMedCrossRef
62.
go back to reference Ozturk A, Simşek T, Yümin ET, Sertel M, Yümin M. The relationship between physical, functional capacity and quality of life (QoL) among elderly people with a chronic disease. Arch Gerontol Geriatr. 2011;53(3):278–83.PubMedCrossRef Ozturk A, Simşek T, Yümin ET, Sertel M, Yümin M. The relationship between physical, functional capacity and quality of life (QoL) among elderly people with a chronic disease. Arch Gerontol Geriatr. 2011;53(3):278–83.PubMedCrossRef
63.
go back to reference Kuyken W, Byford S, Taylor RS, et al. Mindfulness-based cognitive therapy to prevent relapse in recurrent depression. J Consult Clin Psychol. 2008;76(6):966–78.PubMedCrossRef Kuyken W, Byford S, Taylor RS, et al. Mindfulness-based cognitive therapy to prevent relapse in recurrent depression. J Consult Clin Psychol. 2008;76(6):966–78.PubMedCrossRef
64.
go back to reference Godfrin KA, van Heeringen C. The effects of mindfulness-based cognitive therapy on recurrence of depressive episodes, mental health and quality of life: a randomized controlled study. Behav Res Ther. 2010;48(8):738–46.PubMedCrossRef Godfrin KA, van Heeringen C. The effects of mindfulness-based cognitive therapy on recurrence of depressive episodes, mental health and quality of life: a randomized controlled study. Behav Res Ther. 2010;48(8):738–46.PubMedCrossRef
65.
go back to reference Splevins K, Smith A, Simpson J. Do improvements in emotional distress correlate with becoming more mindful? A study of older adults. Aging Ment Health. 2009;13(3):328–35.PubMedCrossRef Splevins K, Smith A, Simpson J. Do improvements in emotional distress correlate with becoming more mindful? A study of older adults. Aging Ment Health. 2009;13(3):328–35.PubMedCrossRef
66.
go back to reference Baer RA. Mindfulness training as a clinical intervention: a conceptual and empirical review. Clin Psychol Sci Pract. 2003;10(2):125–43.CrossRef Baer RA. Mindfulness training as a clinical intervention: a conceptual and empirical review. Clin Psychol Sci Pract. 2003;10(2):125–43.CrossRef
67.
go back to reference Finucane A, Mercer SW. An exploratory mixed methods study of the acceptability and effectiveness of mindfulness-based cognitive therapy for patients with active depression and anxiety in primary care. BMC Psychiatry. 2006;6:14.PubMedCentralPubMedCrossRef Finucane A, Mercer SW. An exploratory mixed methods study of the acceptability and effectiveness of mindfulness-based cognitive therapy for patients with active depression and anxiety in primary care. BMC Psychiatry. 2006;6:14.PubMedCentralPubMedCrossRef
68.
go back to reference Kenny M, Williams JM. Treatment-resistant depressed patients show a good response to mindfulness-based cognitive therapy. Behav Res Ther. 2007;45(3):617–25.PubMedCentralPubMedCrossRef Kenny M, Williams JM. Treatment-resistant depressed patients show a good response to mindfulness-based cognitive therapy. Behav Res Ther. 2007;45(3):617–25.PubMedCentralPubMedCrossRef
69.
go back to reference Fumaz CR, Gonzalez-Garcia M, Borras X, et al. Psychological stress is associated with high levels of IL-6 in HIV-1 infected individuals on effective combined antiretroviral treatment. Brain Behav Immun. 2012;26(4):568–72.PubMedCrossRef Fumaz CR, Gonzalez-Garcia M, Borras X, et al. Psychological stress is associated with high levels of IL-6 in HIV-1 infected individuals on effective combined antiretroviral treatment. Brain Behav Immun. 2012;26(4):568–72.PubMedCrossRef
70.
go back to reference Witek-Janusek L, Albuquerque K, Chroniak KR, Chroniak C, Durazo-Arvizu R, Mathews HL. Effect of mindfulness based stress reduction on immune function, quality of life and coping in women newly diagnosed with early stage breast cancer. Brain Behav Immun. 2008;22(6):969–81.PubMedCentralPubMedCrossRef Witek-Janusek L, Albuquerque K, Chroniak KR, Chroniak C, Durazo-Arvizu R, Mathews HL. Effect of mindfulness based stress reduction on immune function, quality of life and coping in women newly diagnosed with early stage breast cancer. Brain Behav Immun. 2008;22(6):969–81.PubMedCentralPubMedCrossRef
71.
go back to reference Brewer JA, Mallik S, Babuscio TA, et al. Mindfulness training for smoking cessation: results from a randomized controlled trial. Drug Alcohol Depend. 2011;119(1–2):72–80.PubMedCentralPubMedCrossRef Brewer JA, Mallik S, Babuscio TA, et al. Mindfulness training for smoking cessation: results from a randomized controlled trial. Drug Alcohol Depend. 2011;119(1–2):72–80.PubMedCentralPubMedCrossRef
Metadata
Title
Effectiveness of Mindfulness-Based Cognitive Therapy on the Quality of Life, Emotional Status, and CD4 Cell Count of Patients Aging with HIV Infection
Authors
Marian Gonzalez-Garcia
Maria Jose Ferrer
Xavier Borras
Jose A. Muñoz-Moreno
Cristina Miranda
Jordi Puig
Nuria Perez-Alvarez
Joaquim Soler
Albert Feliu-Soler
Bonaventura Clotet
Carmina R. Fumaz
Publication date
01-04-2014
Publisher
Springer US
Published in
AIDS and Behavior / Issue 4/2014
Print ISSN: 1090-7165
Electronic ISSN: 1573-3254
DOI
https://doi.org/10.1007/s10461-013-0612-z

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