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AIDS and Behavior
Published in: AIDS and Behavior 1/2013

01-01-2013 | Original Paper

Association Between Use of Specific Drugs and Antiretroviral Adherence: Findings from MACH 14

Authors: M. I. Rosen, A. C. Black, J. H. Arnsten, K. Goggin, R. H. Remien, J. M. Simoni, C. E. Golin, D. R. Bangsberg, H. Liu

Published in: AIDS and Behavior | Issue 1/2013

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Abstract

To determine the association between individual substances of abuse and antiretroviral adherence, analyses require a large sample assessed using electronic data monitoring (EDM). In this analysis, EDM data from 1,636 participants in 12 US adherence-focused studies were analyzed to determine the associations between recent use of various substances and adherence during the preceding 4 weeks. In bivariate analyses comparing adherence among patients who had used a specific substance to those who had not, adherence was significantly lower among those who had recently used cocaine, other stimulants or heroin but not among those who had used cannabis or alcohol. In multivariate analyses controlling for sociodemographics, amount of alcohol use and recent use of any alcohol, cocaine, other stimulants and heroin each was significantly negatively associated with adherence. The significant associations of cocaine, other stimulants, heroin, and alcohol use with adherence suggest that these are important substances to target with adherence-focused interventions.
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Metadata
Title
Association Between Use of Specific Drugs and Antiretroviral Adherence: Findings from MACH 14
Authors
M. I. Rosen
A. C. Black
J. H. Arnsten
K. Goggin
R. H. Remien
J. M. Simoni
C. E. Golin
D. R. Bangsberg
H. Liu
Publication date
01-01-2013
Publisher
Springer US
Published in
AIDS and Behavior / Issue 1/2013
Print ISSN: 1090-7165
Electronic ISSN: 1573-3254
DOI
https://doi.org/10.1007/s10461-011-0124-7

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