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Published in:

01-06-2007 | Original Paper

Development of the retinal vasculature

Author: Marcus Fruttiger

Published in: Angiogenesis | Issue 2/2007

Abstract

Blood vessels that supply the inner portion of the retina are extensively reorganized during development. The vessel regression, sprouting angiogenesis, vascular remodelling and vessel differentiation events involved critically depend on cell–cell signalling between different cellular components such as neurons, glia, endothelial cells, pericytes and immune cells. Studies in mice using transgenic and gene deletion approaches have started to unravel the genetic basis of some of these signalling pathways and have lead to a much improved understanding of the molecular mechanisms controlling retinal blood vessel behaviour both during development and under pathological conditions. Such insight will provide the basis of future therapeutic approaches aimed at manipulating retinal blood vessels.

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Title: Development of the retinal vasculature
Author: Marcus Fruttiger
Publication date: 01-06-2007
Publisher: Kluwer Academic Publishers
Published in: Angiogenesis / Issue 2/2007
Print ISSN: 0969-6970
Electronic ISSN: 1573-7209
DOI: https://doi.org/10.1007/s10456-007-9065-1

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Abstract

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Year in Review: Heart failure and cardiomyopathies

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

Incentivised to exercise

New intervention for STEMI-related cardiogenic shock

» View more highlights on the ACC 2024 congress hub page

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

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Other articles of this Issue 2/2007

Molecular genetics of AMD and current animal models

Progenitor cells and retinal angiogenesis

Retinopathy of prematurity

Ocular drug development - Future Directions

Vascular permeability in ocular disease and the role of tight junctions

Combination therapy for the treatment of ocular neovascularization

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

Incentivised to exercise

New intervention for STEMI-related cardiogenic shock

» View more highlights on the ACC 2024 congress hub page