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01-06-2004 | Original Article

Whole-body ¹⁸FDG PET plus pelvic MRI in the pre-treatment assessment of cervical cancers: an alternative to the FIGO clinical staging

Author: Tarik Belhocine

Published in: Gynecological Surgery | Issue 2/2004

Abstract

Growing evidence indicates that whole-body ¹⁸F-fluorodeoxyglucose positron emission tomography (wb-¹⁸FDG PET) plus pelvic magnetic resonance imaging (pMRI) may significantly improve the pre-treatment staging of primary cervical cancers. Such a combined protocol provides complementary insights into primary tumour delineation, loco-regional involvement and distant spread. As such, pMRI appears particularly reliable for the accurate measurement of tumour size, the detection of parametrial invasion and, even more so, for its exclusion. So far, wb-¹⁸FDG PET yields unique information about extra-pelvic nodal and visceral tumour status. Of note, however, is the limitation of both imaging techniques for the detection of microscopic pelvic lymph node metastases, especially in early stage disease. Promising data also highlight the prognostic value of ¹⁸FDG uptake as a marker of disease aggressiveness and of tumour resistance to treatment. The recent development of combined PET-CT scans as well as the validation of the sentinel node concept in gynaecological malignancies may grant new perspectives for optimal management of cervical cancers in the pre-treatment setting.

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Title: Whole-body 18FDG PET plus pelvic MRI in the pre-treatment assessment of cervical cancers: an alternative to the FIGO clinical staging
Author: Tarik Belhocine
Publication date: 01-06-2004
Publisher: Springer-Verlag
Published in: Gynecological Surgery / Issue 2/2004
Print ISSN: 1613-2076
Electronic ISSN: 1613-2084
DOI: https://doi.org/10.1007/s10397-004-0021-4

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Whole-body ¹⁸FDG PET plus pelvic MRI in the pre-treatment assessment of cervical cancers: an alternative to the FIGO clinical staging

Abstract

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

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