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Published in: EcoHealth 2/2019

Open Access 01-06-2019 | Toxoplasmosis | Review

The One Health Approach to Toxoplasmosis: Epidemiology, Control, and Prevention Strategies

Authors: A. Alonso Aguirre, Travis Longcore, Michelle Barbieri, Haydee Dabritz, Dolores Hill, Patrice N. Klein, Christopher Lepczyk, Emily L. Lilly, Rima McLeod, Judith Milcarsky, Caroline E. Murphy, Chunlei Su, Elizabeth VanWormer, Robert Yolken, Grant C. Sizemore

Published in: EcoHealth | Issue 2/2019

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Abstract

One Health is a collaborative, interdisciplinary effort that seeks optimal health for people, animals, plants, and the environment. Toxoplasmosis, caused by Toxoplasma gondii, is an intracellular protozoan infection distributed worldwide, with a heteroxenous life cycle that practically affects all homeotherms and in which felines act as definitive reservoirs. Herein, we review the natural history of T. gondii, its transmission and impacts in humans, domestic animals, wildlife both terrestrial and aquatic, and ecosystems. The epidemiology, prevention, and control strategies are reviewed, with the objective of facilitating awareness of this disease and promoting transdisciplinary collaborations, integrative research, and capacity building among universities, government agencies, NGOs, policy makers, practicing physicians, veterinarians, and the general public.
Literature
Afonso E, Lemoine M, Poulle M, Ravat M, Romand S, Thulliez P, Villena I, Aubert D, Rabilloud M, Riche B, Gilot-Fromont E (2008) Spatial distribution of soil contamination by Toxoplasma gondii in relation to cat defecation behavior in an urban area. International Journal of Parasitology 38:1017-1023CrossRefPubMed
Aguirre AA (2011) Developing global capacity in conservation medicine: Predicting and preventing the next epidemic from wildlife. Global Bioethics 24:51-54CrossRef
Aguirre AA, Basu N, Kahn LH, Morin XK, Echaubard P, Wilcox BA, Beasley VR (2019) Transdisciplinary and social-ecological health frameworks—Novel approaches to emerging parasitic and vector-borne diseases. Parasite Epidemiology and Control 4:e00084CrossRef
Aguirre AA, Beasley VR, Augspurger T, Benson WH, Whaley J, Basu N (2016) One health—Transdisciplinary opportunities for SETAC leadership in integrating and improving the health of people, animals, and the environment. Environmental Toxicology and Chemistry 35:2383-2391CrossRefPubMed
Aguirre AA, Keefe TJ, Reif JS, Kashinsky L, Yochem PK, Saliki JT, et al. (2007) Infectious disease monitoring of the endangered Hawaiian monk seal. Journal of Wildlife Diseases 43:229-241CrossRefPubMed
Aguirre AA, Wilcox BA (2008) EcoHealth: Envisioning and creating a truly global transdiscipline. EcoHealth 5:238-239.CrossRefPubMed
Ajzenberg D, Bañuls AL, Su C, Dumètre A, Demar M, Carme B, Dardé ML (2004) Genetic diversity, clonality and sexuality in Toxoplasma gondii. International Journal of Paraitology 34:1185-1196.CrossRef
Arling TA, Yolken RH, Lapidus M, Langenberg P, Dickerson FB, Zimmerman SA, et al. (2009) Toxoplasma gondii antibody titers and history of suicide attempts in patients with recurrent mood disorders. Journal of Nervous and Mental Disease 197:905–908CrossRefPubMed
Azeez R, Prabhakar A (2016) A review of disease inference techniques. International Journal of Science and Research 5:514-518.
Balasundaram MB, Andavar R, Palaniswamy M, Venkatapathy N (2010) Outbreak of acquired ocular toxoplasmosis involving 248 patients. Archives of Ophthalmology 128:28-32CrossRefPubMed
Ballash GA, Dubey J, Kwok O, Shoben AB, Robison TL, Kraft TJ, Dennis PM (2015) Seroprevalence of Toxoplama gondii in white-tailed deer (Odocoileus virginianus) and free-roaming cats (Felis catus) across a suburban to urban gradient in northeastern Ohio. EcoHealth 12:359-367CrossRefPubMed
Barbieri MM, Kashinsky L, Rotstein DS, Colegrove KM, Haman KH, Magargal SL, et al. (2016) Protozoal-related mortalities in endangered Hawaiian monk seals Monachus schauinslandi. Diseases of Aquatic Organisms 121:85-95CrossRefPubMed
Batz MB, Hoffmann S, Morris Jr. JG (2012) Ranking the disease burden of 14 pathogens in food sources in the United States using attribution data from outbreak investigations and expert elicitation. Journal of Food Protection 75:1278-1291.CrossRefPubMed
Berdoy M, Webster JP, Macdonald DW (2000) Fatal attraction in rats infected with Toxoplasma gondii. Proceedings of the Royal Society of Biological Sciences B 267:1591-1594.CrossRef
Bik HM, Maritz JM, Luong A, Shin H, Dominguez-Bello MG, Carlton JM (2016) Microbial community patterns associated with automated teller machine keypads in New York City. mSphere 1:e00226-00216CrossRef
Bowie WR, King AS, Werker DH, Isaac-Renton JL, Bell A, Eng SB, Marion SA (1997) Outbreak of toxoplasmosis associated with municipal drinking water. Lancet 350:173–177CrossRefPubMed
Boyer K, Hill D, Mui E, Wroblewski K, Karrison T, Dubey JP, et al. (2011) Unrecognized ingestion of Toxoplasma gondii oocysts leads to congenital toxoplasmosis and causes epidemics in North America. Clinical Infectious Diseases 53:1081–1089CrossRefPubMedPubMedCentral
Cabezón O, Millan J, Gomis M, Dubey JP, Ferroglio E, Almeria S (2010) Kennel dogs as sentinels of Leishmania infantum, Toxoplasma gondii, and Neospora caninum in Majorca Island, Spain. Parasitology Research 107:1505-1508CrossRefPubMed
Carlson-Bremer D, Colegrove KM, Gulland FM, Conrad PA, Mazet JA, Johnson CK (2015) Epidemiology and pathology of Toxoplasma gondii in free-ranging California sea lions (Zalophus californianus). Journal of Wildlife Diseases 51:362–373CrossRefPubMed
Carme B, Demar M, Ajzenberg D, Dardé ML (2009) Severe acquired toxoplasmosis caused by wild cycle of Toxoplasma gondii, French Guiana. Emerging Infectious Diseases 15:656-658CrossRefPubMedPubMedCentral
Chaichan P, Mercier A, Galal L, Mahittikorn A, Ariey F, Morand S, Bourmédiène F, Udonsom R, Hamidovic A, Murat JB, Sukthana Y, Dardé ML (2017) Geographical distribution of Toxoplasma gondii genotypes in Asia: A link with neighboring countries. Infection, Genetics and Evolution 53:227-238.CrossRefPubMed
Chomel BB, Zarnke RL, Kasten RW, Kass PH, Mendes E (1995) Serologic survey of Toxoplasma gondii in grizzly bears (Ursus arctos) and black bears (Ursus americanus), from Alaska, 1988 to 1991. Journal of Wildlife Diseases 31:472-479CrossRefPubMed
Cole RA, Lindsay DS, Howe DK, Roderick CL, Dubey JP, Thomas NJ, Baeten LA (2000) Biological and molecular characterizations of Toxoplasma gondii strain obtained from southern sea otters (Enhydra lutris nereis). Journal of Parasitology 86:526–530CrossRefPubMed
Conrad PA, Miller MA, Kreuder C, James ER, Mazet J, Dabritz H, et al. (2005) Transmission of Toxoplasma: clues from the study of sea otters as sentinels of Toxoplasma gondii flow into the marine environment. International Journal for Parasitology 35:1155–1168CrossRefPubMed
Crozier G, Schulte-Hostedde AI (2014) The ethical dimensions of wildlife disease management in an evolutionary context. Evolutionary Applications 7:788-798CrossRefPubMedPubMedCentral
Dabritz HA, Miller MA, Atwill ER, Gardner IA, Leutenegger CM, Melli AC, Conrad PA (2007) Detection of Toxoplasma gondii-like oocysts in cat feces and estimates of the environmental oocyst burden. Journal of the American Veterinary Medical Association 231:1676-1684.CrossRefPubMed
Dabritz HA, Conrad PA (2010) Cats and Toxoplasma: implications for public health. Zoonoses and Public Health 57:34–52CrossRefPubMed
Dardé ML (2004) Genetic analysis of the diversity in Toxoplasma gondii. Annali dell’Istituto Superiore di Sanità 40:57-63PubMed
Delair E, Latkany P, Noble AG, Rabiah P, McLeod R, Brezin A (2011) Clinical manifestations of ocular toxoplasmosis. Ocular Immunology and Inflammation 19:91-102CrossRefPubMed
Dixon B (2016) Emerging markets and parasitic diseases. In: One Health Case Studies. Cork S, Hall D, Liljebjelke K (editors), 5 M Publishing Ltd., Sheffield, UK, pp. 245-258.
Du F, Zhang Q, Yu Q, Hu M, Zhou Y, Zhao J (2012a) Soil contamination of Toxoplasma gondii oocysts in pig farms in central China. Veterinary Parasitology 187: 53-56.CrossRefPubMed
Du F, Feng HL, Nie H, Tu P, Zhang QL, Hu M, Zhou YQ, Zhao JL (2012b). Survey on the contamination of Toxoplasma gondii oocysts in the soil of public parks of Wuhan, China. Veterinary Parasitology 184:141-146CrossRefPubMed
Dubey JP (1996) Infectivity and pathogenicity of Toxoplasma gondii oocysts for cats. Journal of Parasitology 82:957-961CrossRefPubMed
Dubey JP (2010) Toxoplasmosis of Animals and Humans, CRC Press, Boca Raton, Florida
Dubey JP, Jones JL (2008) Toxoplasma gondii infection in humans and animals in the United States. International Journal for Parasitology 38:1257–1278CrossRefPubMed
Dubey JP, Lindsay DS, Lappin MR (2009) Toxoplasmosis and other intestinal coccidial infections in cats and dogs. Veterinary Clinics of North America: Small Animal Practice 39:1009-1034CrossRefPubMed
Dubey JP, Lunney JK, Shen SK, Kwok OCH, Ashford DA, Thulliez P (1996) Infectivity of low numbers of Toxoplasma gondii oocysts to pigs. Journal of Parasitology 82:438-443CrossRefPubMed
Dubey JP, Lago EG, Gennari SM, Su C, Jones JL (2012) Toxoplasmosis in humans and animals in Brazil: high prevalence, high burden of disease, and epidemiology. Parasitology 139:1375-1424CrossRefPubMed
Dubey JP, Dennis P, Verma S, Choudhary S, Ferreira L, Oliveira S, et al. (2014) Epidemiology of toxoplasmosis in white tailed deer (Odocoileus virginianus): Occurrence, congenital transmission, correlates of infection, isolation, and genetic characterization of Toxoplasma gondii. Veterinary Parasitology 202:270-275CrossRefPubMed
Dubey JP, Zarnke R, Thomas N, Wong S, Van Bonn W, Briggs M, et al. (2003) Toxoplasma gondii, Neospora caninum, Sarcocystis neurona, and Sarcocystis canis-like infections in marine mammals. Veterinary Parasitology 116:275-296CrossRefPubMed
Dubey JP, Lipscomb TP, Mense M (2004) Toxoplasmosis in an elephant seal (Mirounga angustirostris). Journal of Parasitology 90:410–411CrossRefPubMed
Flegr J, Prandota J, Sovičková M, Israili ZH (2014) Toxoplasmosis—a global threat. Correlation of latent toxoplasmosis with specific disease burden in a set of 88 countries. PLoS ONE 9:e90203CrossRefPubMedPubMedCentral
Flegr J, Havlíček J, Kodym P, Malý M, Smahel Z (2002) Increased risk of traffic accidents in subjects with latent toxoplasmosis: a retrospective case-control study. BMC Infectious Diseases 2:11.CrossRefPubMedPubMedCentral
Flegr J, Klose J, Novotná M, Berenreitterová M, Havlíček J (2009) Increased incidence of traffic accidents in Toxoplasma-infected military drivers and protective effect RhD molecule revealed by a large-scale prospective cohort study. BMC Infectious Diseases 9:72.CrossRefPubMedPubMedCentral
Fredebaugh SL, Mateus-Pinilla NE, McAllister M, Warner RE, Weng H-Y (2011) Prevalence of antibody to Toxoplasma gondii in terrestrial wildlife in a natural area. Journal of Wildlife Diseases 47:381–392CrossRefPubMed
Frenkel JK, Lindsay DS, Parker BB, Dobesh M (2003) Dogs as possible mechanical carriers of Toxoplasma, and their fur as a source of infection of young children. International Journal of Infectious Diseases 7:292–293CrossRefPubMed
Frenkel JK, Ruiz A, Chinchilla M (1975) Soil survival of toxoplasma oocysts in Kansas and Costa Rica. American Journal of Tropical Medicine and Hygiene 24:439-443.CrossRefPubMed
Gao X, Wang H, Wang H, Qin H, Xiao J (2016) Land use and soil contamination with Toxoplasma gondii oocysts in urban areas. Science of the Total Environment 568:1086-1091CrossRefPubMed
Gajewski PD, Falkenstein M, Hengstler JG, Golka K (2014) Toxoplasma gondii impairs memory in infected seniors. Brain, Behavior, and Immunity 36:193-199CrossRefPubMed
Georgi JR (1985) Protozoans in: Parasitology for Veterinarians, 4th Edition. WB Saunders:62-72
Gortazar C, Reperant LA, Kuiken T, de la Fuente J, Boadella M, Martínez-Lopez B, et al. (2014) Crossing the interspecies barrier: opening the door to zoonotic pathogens. PLoS Pathogens 10:e1004129CrossRefPubMedPubMedCentral
Guo M, Mishra A, Buchanan RL, Dubey JP, Hill DE, Gamble HR et al. (2016) A systematic meta-analysis of Toxoplasma gondii prevalence in food animals in the United States. Foodborne Pathogens and Disease 13:109-118CrossRefPubMed
Hill D, Coss C, Dubey JP, Wroblewski K, Sautter M, Hosten T, et al. (2011) Identification of a sporozoite-specific antigen from Toxoplasma gondii. Journal of Parasitology 97:328–337CrossRefPubMed
Hill D, Dubey JP (2013) Toxoplasma gondii prevalence in farm animals in the United States. International Journal for Parasitology 43:107-113CrossRefPubMed
Hill DE, Dubey JP (2014) Toxoplasmosis, Reston, VA: U.S. Geological Survey Circular 1389, 84 pp
Hill DE, Dubey JP (2016) Toxoplasma gondii as a parasite in food: analysis and control. Microbiology Spectrum 4:1-17
Hill DE, Chirukandoth S, Dubey JP (2005) Biology and epidemiology of Toxoplasma gondii in man and animals. Animal Health Research Reviews 6:41-61CrossRefPubMed
Hoffmann S, Batz MB, Morris Jr JG (2012) Annual cost of illness and quality-adjusted life year losses in the United States due to 14 Foodborne Pathogens. Journal of Food Protection 75:1292-1302.CrossRefPubMed
Holshuh H, Sherrod A, Taylor C, Andrews B, Howard E (1985) Toxoplasmosis in a feral northern fur seal. Journal of the American Veterinary Medical Association 187:1229-1230PubMed
Holtz E (2014) Trap-Neuter-Return ordinances and policies in the United States: the future of animal control, Bethesda, Maryland: Alley Cat Allies, 12 pp
Howe DK, Sibley LD (1995) Toxoplasma gondii comprises three clonal lineages: correlation of parasite genotype with human disease. Journal of Infectious Diseases 172: 1561-1566.CrossRefPubMed
Inskeep W II, Gardiner C, Harris R, Dubey JP, Goldston R (1990) Toxoplasmosis in Atlantic bottle-nosed dolphins (Tursiops truncatus). Journal of Wildlife Diseases 26:377-382CrossRefPubMed
Jardine J, Dubey JP (2002) Congenital toxoplasmosis in a Indo-Pacific bottlenose dolphin (Tursiops aduncus). Journal of Parasitology 88:197-199CrossRefPubMed
Jenkins EJ, Simon A, Bachand N, Stephen C (2015) Wildlife parasites in a One Health world. Trends in Parasitology 31:174-180CrossRefPubMed
Jensen S, Nymo I, Forcada J, Godfroid J, Hall A (2012) Prevalence of Toxoplasma gondii antibodies in pinnipeds from Antarctica. Microbiology 11:562-568
Jessup DA, M Miller, J Ames, M Harris, C Kreuder, PA Conrad, JAK Mazet (2004) Southern sea otter as a sentinel of marine ecosystem health. EcoHealth 1:239-245.CrossRef
Johnson CK, Tinker TM, Estes JA, Conrad PA, Staedler M, Miller MA, Jessup DA, and Mazet JAK (2009) Prey choice and habitat use drive sea otter pathogen exposure in a resource-limited coastal system. Proceedings of the National Academy of Sciences USA 106(7):2242-2247CrossRef
Jones JL, Kruszon-Moran D, Elder S, Rivera HN, Press C, Montoya JG, McQuillan GM (2018) Toxoplasma gondii infection in the United States, 2011-2014. American Journal of Tropical Medical Hygiene 98:551-557CrossRef
Jones JL, Holland GN (2010) Annual burden of ocular toxoplasmosis in the United States. American Journal of Tropical Medicine Hygiene 82:464-465CrossRefPubMed
Jones, JL, Kruszon-Moran D, Sanders-Lewis K, Wilson M (2007) Toxoplasma gondii infection in the United States, 1999-2004, decline from the prior decade. American Journal of Tropical Medicine and Hygiene 77:405-410.CrossRefPubMed
Jones JL, Kruszon-Moran D, Wilson M, McQuillan G, Navin T, McAuley JB (2001) Toxoplasma gondii infection in the United States: seroprevalence and risk factors. American Journal of Epidemiology 154:357-365.CrossRefPubMed
Khan A, Dubey JP, Su C, Ajioka JW, Rosenthal BM, Sibley LD (2011) Genetic analyses of typical Toxoplasma gondii strains reveal a fourth clonal lineage in North America. International Journal of Parasitology 41:645-655.CrossRefPubMed
Kianersi F, Nadarei Beni A, Ghanbari H, Fazel F (2012) Ocular toxoplasmosis and retinal detachment: five case reports. European Review for Medical and Pharmacological Sciences 16:84-89PubMed
Lehmann T, Marcet PL, Graham DH, Dahl ER, Dubey JP (2006) Globalization and the population structure of Toxoplasma gondii. Proceedings of the National Academy of Sciences of the United States of America 103:11423-11428CrossRefPubMedPubMedCentral
Lélu M, Langlais M, Poulle M-L, Gilot-Fromont E (2010) Transmission dynamics of Toxoplasma gondii along an urban–rural gradient. Theoretical Population Biology 78:139-147CrossRefPubMed
Lélu M, Villena I, Dardé M-L, Aubert D, Geers R, Dupuis E, et al. (2012) Quantitative estimation of the viability of Toxoplasma gondii oocysts in soil. Applied and Environmental Microbiology 78:5127-5132CrossRefPubMedPubMedCentral
Levy JK, Crawford PC (2004) Humane strategies for controlling feral cat populations. Journal of the American Veterinary Medical Association 225:1354–1360CrossRefPubMed
Lindsay DS, Dubey JP (2009) Long-term survival of Toxoplasma gondii sporulated oocysts in seawater. Journal of Parasitology 95:1019-1020CrossRefPubMed
Littnan CL, Stewart BS, Yochem PK, Braun R (2006) Survey for selected pathogens and evaluation of disease risk factors for endangered Hawaiian monk seals in the main Hawaiian Islands. EcoHealth 3:232-244CrossRef
Lohr CA, Lepczyk CA (2014) Desires and management preferences of stakeholders regarding feral cats in the Hawaiian Islands. Conservation Biology 28:392-403CrossRefPubMed
Longcore T, Rich C, Sullivan LM (2009) Critical assessment of claims regarding management of feral cats by trap-neuter-return. Conservation Biology 23:887-894CrossRefPubMed
Lorenzi H, Khan A, Behnke MS, Namasivayam S, Swapna LS, Hadjithomas M, et al (2016) Local admixture of amplified and diversified secreted pathogenesis determinants shapes mosaic Toxoplasma gondii genomes Nature Communications 7:10147.CrossRefPubMedPubMedCentral
Loss SR, Will T, Marra PP (2015) Direct mortality of birds from anthropogenic causes. Annual Review of Ecology, Evolution, and Systematics 46:99-120.CrossRef
Loss SR, Marra PP (2018) Merchants of doubt in the free-ranging cat conflict. Conservation Biology 32:265-266.CrossRefPubMed
Lykins J, Wang K, Wheeler K, Clouser F, Dixon A, Bassati KE, et al. (2016) Understanding toxoplasmosis in the United States through “large data” analyses. Clinical Infectious Diseases 63: 468-475CrossRefPubMedPubMedCentral
Markell EK (1986) Other Blood-and Tissue-Dwelling Protozoa in: Medical Parasitology, 6th Edition. WB Saunders Co: 131-138.
Massolo A, Liccioli S (2016) Applying One Health, multi-scale approach to understanding and preventing zoonotic parasite transmission in urban ecosystems: Echinococcus multilocularis and alveolar echinococcoicis in North America. In: One Health Case Studies. Cork S, Hall D, Liljebjelke K (editors), 5M Publishing Ltd., Sheffield, UK, pp. 40-53.
McAuley J, Boyer KM, Patel D, Mets M, Swisher C, Roizen N, et al. (1994) Early and longitudinal evaluations of treated infants and children and untreated historical patients with congenital toxoplasmosis: the Chicago Collaborative Treatment Trial. Clinical Infectious Diseases 18: 38-72CrossRefPubMed
McLeod R, Lykins J, Noble A.G, Rabiah P, Swisher CN, Heydemann PT, et al. (2014) Management of congenital toxoplasmosis. Current Pediatrics Reports 2:166-194CrossRef
Mead PS. Slutsker L, Dietz V, McCaig LF, Bresee JS, Shapiro C, Griffin PM, Tauxe RV (1999) Food-related illness and death in the United States. Emerging Infectious Diseases 5:607–625.CrossRefPubMedPubMedCentral
Migaki G, Sawa T, Dubey JP (1990) Fatal disseminated toxoplasmosis in a spinner dolphin (Stenella longirostris). Veterinary Pathology 27:463-464CrossRefPubMed
Miller MA, Gardner IA, Kreuder C, Paradies DM, Worcester KR, Jessup DA, et al. (2002) Coastal freshwater runoff is a risk factor for Toxoplasma gondii infection of southern sea otters (Enhydra lutris nereis). International Journal for Parasitology 32:997–1006CrossRefPubMed
Miller MA, Grigg ME, Kreuder C, James ER, Melli AC, Crosbie PR, Jessup DA, Boothroyd JC, Brownstein D, Conrad PA (2004) An unusual genotype of Toxoplasma gondii is common in California sea otters (Enhydra lutris nereis) and is a cause of mortality. International Journal of Parasitology 34:275-284.CrossRefPubMed
Miller MA, Miller WA, Conrad PA, James ER, Melli AC, Leutenegger CM, et al. (2008) Type X Toxoplasma gondii in a wild mussel and terrestrial carnivores from coastal California: new linkages between terrestrial mammals, runoff and toxoplasmosis of sea otters. International Journal for Parasitology 38:1319–1328CrossRefPubMed
Miller NL, Frenkel J, Dubey JP (1972) Oral infections with Toxoplasma cysts and oocysts in felines, other mammals, and in birds. Journal of Parasitology 58:928-937CrossRefPubMed
Minbaeva G, Schweiger A, Bodosheva A, Kuttubaev O, Hehl AB, Tanner I, Ziadinov I, Torgerson PR, Deplazes P (2013) Toxoplasma gondii infection in Kyrgyzstan: Seroprevalence, risk factor analysis, and estimate of congenital and AIDS-related toxoplasmosis. PLoS Neglected Tropical Diseases 7:e2043CrossRefPubMedPubMedCentral
Montoya JG, Remington JS (1995) Studies on the serodiagnosis of toxoplasmic lymphadentis. Clinical Infectious Diseases 20:781-789CrossRefPubMed
Muñoz-Zanzi CA, Fry P, Lesina B, Hill D (2010) Toxoplasma gondii oocyst–specific antibodies and source of infection. Emerging Infectious Diseases 16:1591CrossRefPubMedPubMedCentral
Muñoz-Zanzi CA, Tamayo R, Balboa J, Hill D (2012) Detection of oocyst-associated toxoplasmosis in swine from southern Chile. Zoonoses and Public Health 59:389-392CrossRefPubMed
Ngo HM, Zhou Y, Lorenzi H, Wang K, Kim T, Zhou Y, et al. (2017) Toxoplasma modulcates signature pathways of human epilepsy, neurodegeneration, and cancer. Scientific Reports 7:11496CrossRefPubMedPubMedCentral
Nunes Mecca J, Meireles LR, Franco de Andrade Jr H (2011) Quality control of Toxoplasma gondii in meat packages: Standardization of an ELISA test and its use for detection in rabbit meat cuts. Meat Science 88:584-589CrossRef
Oksanen A, Åsbakk K, Prestrud K, Aars J, Derocher A, Tryland M, et al. (2009) Prevalence of antibodies against Toxoplasma gondii in polar bears (Ursus maritimus) from Svalbard and East Greenland. Journal of Parasitology 95:89-94CrossRefPubMed
Ortiz S, Martin R, de Juan V (2013) Ocular toxoplasmosis: A case report. International Journal of Clinical Medicine 4:1-4.CrossRef
Peyron F, McLeod R, Ajzenberg D, Contopoulos-Inoannidis D, Kieffer F, Mandelbrot L, et al. (2017) Congenital toxoplasmosis in France and the United States: one parasite, two diverging approaches. PloS Neglected Tropical Diseases 11:e0005222.CrossRefPubMedPubMedCentral
Peyron F, Wallon M, Kieffer F, Garweg J (2016) Toxoplasmosis In: Remnington and Klein’s Infectious Diseases of the Fetus and Newborn Infant 8th ed. Wilson CB, Nizet V, Maldonado YA, Remington JS, Klein JO (editors), Elsevier Saunders., Philadelphia, pp 949-1042
Poirotte C, Kappeler PM, Ngoubangoye B, Bourgeois S, Moussodji M, Charpentier MJE (2016) Morbid attraction to leopard urine in Toxoplasma-infected chimpanzees. Current Biology 26:R83-R101CrossRef
Rengifo-Herrera C, Ortega-Mora LM, Álvarez-García G, Gómez-Bautista M, García-Párraga D, García-Peña FJ, Pedraza-Díaz S (2012) Detection of Toxoplasma gondii antibodies in Antarctic pinnipeds. Veterinary Parasitology 190:259-262CrossRefPubMed
Rubin C, Dunham B, Sleeman J (2014) Making One Health a reality—crossing bureaucratic boundaries. Microbiology Spectrum 2:OH-0016-2012PubMed
Saeij JP, Boyle JP, Boothroyd JC (2005) Differences among the three major strains of Toxoplasma gondii and their specific interactions with the infected host. Trends in Parasitology 21:476-481.CrossRefPubMed
Scallan E, Hoekstra RM, Angulo FJ, Tauxe RV, Widdowson M, Roy SL, et al. (2011) Foodborne illness acquired in the United States—major pathogens. Emerging Infectious Diseases 17:7-15CrossRefPubMedPubMedCentral
Shapiro K, C Krusor, FFM Mazzillo, PA Conrad, JL Largier, JAK Mazet (2014) Aquatic polymers can drive pathogen transmission in coastal ecosystems Proceedings of the Royal Society B 281:1785CrossRef
Shwab EK, Zhu X-Q, Majumdar D, Pena HF, Gennari SM, Dubey JP, Su C (2014) Geographical patterns of Toxoplasma gondii genetic diversity revealed by multilocus PCR-RFLP genotyping. Parasitology 141:453-461CrossRefPubMed
Sibley LD, Boothroyd JC (1992) Virulent strains of Toxoplasma gondii compromise a single clonal lineage. Nature 359(6390):82-85.CrossRefPubMed
Sroka J, Wójcik-Fatla A, Dutkiewicz J (2006) Occurrence of Toxoplasma gondii in water from wells located on farms. Annals of Agricultural and Environmental Medicine 13:169–175PubMed
Su C, Khan A, Zhou P, Majumdar D, Ajzenberg D, Dardé ML, Zhu XQ, Ajioka JW, Rosenthal BM, Dubey JP, Sibley LD (2012) Globally diverse Toxoplasma gondii isolates comprise six major clades originating from a small number of distinct ancestral lineages. Proceeding s of the National Academy of Sciences USA 109:5844-5849.CrossRef
Suvisaari J, Torniainen-Holm M, Lindgren M, Harkanen T, Yolken RH (2017) Toxoplasma gondii infection and common mental disorders in the Finnish general population. Journal of Affective Disorders 223: 20-25CrossRefPubMedPubMedCentral
Suzán G, García-Peña GE, Castro-Arellano I, Rico O, Rubio AV, Tolsá MJ, et al. (2015) Metacommunity and phylogenetic structure determine wildlife and zoonotic infectious disease patterns in time and space. Ecology and Evolution 5:865-873CrossRefPubMedPubMedCentral
Thompson RCA (2013) Parasite zoonoses and wildlife: One Health, spillover and human activity. International Journal of Parasitology 43:1079-1088.CrossRefPubMed
Torgerson PR, Mastroiacovo P (2013) The global burden of congenital toxoplasmosis: a systematic review. Bulletin of the World Health Organization 91:501-508CrossRefPubMedPubMedCentral
Torrey EF, Yolken RH (2013) Toxoplasma oocysts as a public health problem. Trends in Parasitology 29:380–384CrossRefPubMed
Undseth Ø, Gerlyng P, Goplen AK, Holter ES, von der Lippe E, Dunlop O (2014) Primary toxoplasmosis with critical illness and multi-organ failure in an immunocompetent young man. Scandinavian Journal of Infectious Diseases 46:58-62CrossRefPubMed
VanWormer E, Carpenter TE, Singh P, Shapiro K, Wallender WW, Conrad PA, et al. (2016) Coastal development and precipitation drive pathogen flow from land to sea: evidence from a Toxoplasma gondii and felid host system. Scientific Reports 6:29252CrossRefPubMedPubMedCentral
VanWormer E, Conrad PA, Miller MA, Melli AC, Carpenter TE, Mazet JAK (2013) Toxoplasma gondii, source to sea: higher contribution of domestic felids to terrestrial parasite loading despite lower infection prevalence. EcoHealth 10:277-289CrossRefPubMed
VanWormer E, Miller MA, Conrad PA, Grigg ME, Rejmanek D, Carpenter TE, Mazet JA (2014) Using molecular epidemiology to track Toxoplasma gondii from terrestrial carnivores to marine hosts: implications for public health and conservation. PLoS Neglected Tropical Diseases 8:e2852CrossRefPubMedPubMedCentral
Verma SK, Sweeny AR, Lovallo MJ, Calero-Bernal R, Kwok OC, Jiang T, et al. (2017) Seroprevalence, isolation and co-infection of multiple Toxoplasma gondii strains in individual bobcats (Lynx rufus) from Mississippi, USA. International Journal for Parasitology 47:297-303CrossRefPubMed
Vesco G, Buffolano W, La Chiusa S, Mancuso G, Caracappa S, Chianca A, et al. (2007) Toxoplasma gondii infections in sheep in Sicily, southern Italy. Veterinary Parasitology 146:3–8CrossRefPubMed
Vinetz JM, Wilcox BA, Aguirre AA, Gollin LX, Katz AR, Fujikoya RS, Maly K, Horwitz P, Chang H (2005) Beyond disciplinary boundaries: Leptospirosis as a model of incorporating transdisciplinary approaches to understand disease emergence. EcoHealth 2:291-306CrossRef
Vollaire MR, Radecki SV, Lappin MR (2005) Seroprevalence of Toxoplasma gondii antibodies in clinically ill cats in the United States. American Journal of Veterinary Research 66: 874-877CrossRefPubMed
Vyas A, Kim SK, Giacomini N, Boothroyd JC, Sapolsky RM (2007) Behavioral changes induced by Toxoplasma infection in rodents are highly specific to aversion of cat odors. Proceedings of the National Academy of Sciences USA 104:6442-6447.CrossRef
Wang ZD., Liu HH, Ma ZX, Ma HY, Li ZY, Yang ZB, et al. (2017) Toxoplasma gondii infection in immunocompromised patients: a systematic review and meta-analysis. Frontiers in Microbiology 8:389.PubMedPubMedCentral
Wendte JM, Gibson AK, Grigg ME (2011) Population genetics of Toxoplasma gondii: new perspectives from parasite genotypes in wildlife. Veterinary Parasitology 182:96-111CrossRefPubMedPubMedCentral
Wilking H, Thamm M, Stark K, Aebischer T, Seeber F (2016) Prevalence, incidence estimations, and risk factors of Toxoplasma gondii infection in Germany: a representative, cross-sectional, serological study. Scientific Reports 6:22551CrossRefPubMedPubMedCentral
Work TM., Verma SK, Su C, Medeiros J, Kaiakapu T, Kwok OC, Dubey JP (2016) Toxoplasma gondii antibody prevalence and two new genotypes of the parasite in endangered Hawaiian geese (Nene: Branta sandvicensis). Journal of Wildlife Diseases 52:253-257CrossRefPubMed
Xiao J, Yolken RH (2015) Strain hypothesis of Toxoplasma gondii infection on the outcome of human diseases. Acta Physiologica 213:828-845CrossRefPubMed
Xiao J, Li Y, Prandovszky E, Kannan G, Viscidi RP, Pletnikov MV, Yolken RH (2016) Behavioral abnormalities in a mouse model of chronic toxoplasmosis are associated with MAG1 antibody levels and cyst burden. PloS Neglected Tropical Diseases 10:e0004674CrossRefPubMedPubMedCentral
Yolken RH, Dickerson FB, Torrey EF (2009) Toxoplasma and schizophrenia. Parasite Immunology 31:706–715CrossRefPubMed
Metadata
Title
The One Health Approach to Toxoplasmosis: Epidemiology, Control, and Prevention Strategies
Authors
A. Alonso Aguirre
Travis Longcore
Michelle Barbieri
Haydee Dabritz
Dolores Hill
Patrice N. Klein
Christopher Lepczyk
Emily L. Lilly
Rima McLeod
Judith Milcarsky
Caroline E. Murphy
Chunlei Su
Elizabeth VanWormer
Robert Yolken
Grant C. Sizemore
Publication date
01-06-2019
Publisher
Springer US
Keyword
Toxoplasmosis
Published in
EcoHealth / Issue 2/2019
Print ISSN: 1612-9202
Electronic ISSN: 1612-9210
DOI
https://doi.org/10.1007/s10393-019-01405-7

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