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Published in: Journal of Public Health 6/2018

Open Access 01-12-2018 | Original Article

Vitamin D deficiency was common in all patients at a Swedish primary care centre, but more so in patients born outside of Europe

Authors: Per Wändell, Sahar Ayoob, Lennart Mossberg, Anna Andreasson

Published in: Journal of Public Health | Issue 6/2018

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Abstract

Background

Vitamin D is associated with extra-skeletal processes, and vitamin D deficiency might contribute to the development of chronic diseases.

Aim

To investigate vitamin D levels in an unselected patient population at a Swedish suburban primary care centre.

Methods

Vitamin D levels were assessed in 102 patients aged 20 to 65 years visiting the primary care centre, independent of cause of visit, during 2 weeks in January 2014. The difference in vitamin D levels between patients born in Europe and patients born outside Europe was calculated using linear regression, adjusting for gender and age. The difference in prevalence of vitamin D deficiency (< 25 nmol/l) was calculated using logistic regression adjusting for gender, age, vitamin D supplement, and sun exposure.

Results

Patients born outside Europe (n = 66) had 15 nmol/l [95% confidence interval (CI) 9.17–20.84] lower levels of vitamin D than patients born in Europe. Vitamin D deficiency was more common in patients born outside Europe (50%) than in patients born in Europe (11%, odds ratio 8.20 95% CI 2.49–26.98, p < 0.001).

Conclusion

Lower levels of vitamin D and the prevalence of vitamin D deficiency were more common in patients born outside Europe compared to patients born in Europe.
Literature
go back to reference Brunvand L, Quigstad E, Urdal P, Haug E (1996) Vitamin D deficiency and fetal growth. Early Hum Dev 45:27–33CrossRef Brunvand L, Quigstad E, Urdal P, Haug E (1996) Vitamin D deficiency and fetal growth. Early Hum Dev 45:27–33CrossRef
go back to reference Danescu LG, Levy S, Levy J (2009) Vitamin D and diabetes mellitus. Endocrine 35:11–17CrossRef Danescu LG, Levy S, Levy J (2009) Vitamin D and diabetes mellitus. Endocrine 35:11–17CrossRef
go back to reference Durup D, Jorgensen HL, Christensen J, Tjonneland A, Olsen A, Halkjaer J, Lind B, Heegaard AM, Schwarz P (2015) A reverse J-shaped association between serum 25-Hydroxyvitamin D and cardiovascular disease mortality: the CopD study. J Clin Endocrinol Metab 100:2339–2346CrossRef Durup D, Jorgensen HL, Christensen J, Tjonneland A, Olsen A, Halkjaer J, Lind B, Heegaard AM, Schwarz P (2015) A reverse J-shaped association between serum 25-Hydroxyvitamin D and cardiovascular disease mortality: the CopD study. J Clin Endocrinol Metab 100:2339–2346CrossRef
go back to reference Elidrissy AT, Sedrani SH, Lawson DE (1984) Vitamin D deficiency in mothers of rachitic infants. Calcif Tissue Int 36:266–268CrossRef Elidrissy AT, Sedrani SH, Lawson DE (1984) Vitamin D deficiency in mothers of rachitic infants. Calcif Tissue Int 36:266–268CrossRef
go back to reference Forslund T, Wettermark B, Wandell P, von Euler M, Hasselstrom J, Hjemdahl P (2014) Risks for stroke and bleeding with warfarin or aspirin treatment in patients with atrial fibrillation at different CHA(2)DS(2)VASc scores: experience from the Stockholm region. Eur J Clin Pharmacol 70:1477–1485CrossRef Forslund T, Wettermark B, Wandell P, von Euler M, Hasselstrom J, Hjemdahl P (2014) Risks for stroke and bleeding with warfarin or aspirin treatment in patients with atrial fibrillation at different CHA(2)DS(2)VASc scores: experience from the Stockholm region. Eur J Clin Pharmacol 70:1477–1485CrossRef
go back to reference Garland CF, Gorham ED, Mohr SB, Garland FC (2009) Vitamin D for cancer prevention: global perspective. Ann Epidemiol 19:468–483CrossRef Garland CF, Gorham ED, Mohr SB, Garland FC (2009) Vitamin D for cancer prevention: global perspective. Ann Epidemiol 19:468–483CrossRef
go back to reference Grant WB, Juzeniene A, Moan JE (2011) Review article: health benefit of increased serum 25(OH)D levels from oral intake and ultraviolet-B irradiance in the Nordic countries. Scand J Public Health 39:70–78CrossRef Grant WB, Juzeniene A, Moan JE (2011) Review article: health benefit of increased serum 25(OH)D levels from oral intake and ultraviolet-B irradiance in the Nordic countries. Scand J Public Health 39:70–78CrossRef
go back to reference Holick MF, Chen TC (2008) Vitamin D deficiency: a worldwide problem with health consequences. Am J Clin Nutr 87:1080S–1086SCrossRef Holick MF, Chen TC (2008) Vitamin D deficiency: a worldwide problem with health consequences. Am J Clin Nutr 87:1080S–1086SCrossRef
go back to reference Holvik K, Meyer HE, Haug E, Brunvand L (2005) Prevalence and predictors of vitamin D deficiency in five immigrant groups living in Oslo, Norway: the Oslo Immigrant Health Study. Eur J Clin Nutr 59:57–63CrossRef Holvik K, Meyer HE, Haug E, Brunvand L (2005) Prevalence and predictors of vitamin D deficiency in five immigrant groups living in Oslo, Norway: the Oslo Immigrant Health Study. Eur J Clin Nutr 59:57–63CrossRef
go back to reference Lips P (2007) Vitamin D status and nutrition in Europe and Asia. J Steroid Biochem Mol Biol 103:620–625CrossRef Lips P (2007) Vitamin D status and nutrition in Europe and Asia. J Steroid Biochem Mol Biol 103:620–625CrossRef
go back to reference Lips P (2010) Worldwide status of vitamin D nutrition. J Steroid Biochem Mol Biol 121:297–300CrossRef Lips P (2010) Worldwide status of vitamin D nutrition. J Steroid Biochem Mol Biol 121:297–300CrossRef
go back to reference Meyer HE, Holvik K, Lofthus CM, Tennakoon SU (2008) Vitamin D status in Sri Lankans living in Sri Lanka and Norway. Br J Nutr 99:941–944CrossRef Meyer HE, Holvik K, Lofthus CM, Tennakoon SU (2008) Vitamin D status in Sri Lankans living in Sri Lanka and Norway. Br J Nutr 99:941–944CrossRef
go back to reference Michaelsson K, Baron JA, Snellman G, Gedeborg R, Byberg L, Sundstrom J, Berglund L, Arnlov J, Hellman P, Blomhoff R, Wolk A, Garmo H, Holmberg L, Melhus H (2010) Plasma vitamin D and mortality in older men: a community-based prospective cohort study. Am J Clin Nutr 92:841–848CrossRef Michaelsson K, Baron JA, Snellman G, Gedeborg R, Byberg L, Sundstrom J, Berglund L, Arnlov J, Hellman P, Blomhoff R, Wolk A, Garmo H, Holmberg L, Melhus H (2010) Plasma vitamin D and mortality in older men: a community-based prospective cohort study. Am J Clin Nutr 92:841–848CrossRef
go back to reference Oksuzyan A, Juel K, Vaupel JW, Christensen K (2008) Men: good health and high mortality. Sex differences in health and aging. Aging Clin Exp Res 20:91–102CrossRef Oksuzyan A, Juel K, Vaupel JW, Christensen K (2008) Men: good health and high mortality. Sex differences in health and aging. Aging Clin Exp Res 20:91–102CrossRef
go back to reference van der Meer IM, Middelkoop BJ, Boeke AJ, Lips P (2011) Prevalence of vitamin D deficiency among Turkish, Moroccan, Indian and sub-Sahara African populations in Europe and their countries of origin: an overview. Osteoporos Int 22:1009–1021CrossRef van der Meer IM, Middelkoop BJ, Boeke AJ, Lips P (2011) Prevalence of vitamin D deficiency among Turkish, Moroccan, Indian and sub-Sahara African populations in Europe and their countries of origin: an overview. Osteoporos Int 22:1009–1021CrossRef
go back to reference Wandell PE (2013) Population groups in dietary transition. Food Nutr Res 57CrossRef Wandell PE (2013) Population groups in dietary transition. Food Nutr Res 57CrossRef
go back to reference Zarrinkoub R, Wettermark B, Wandell P, Mejhert M, Szulkin R, Ljunggren G, Kahan T (2013) The epidemiology of heart failure, based on data for 2.1 million inhabitants in Sweden. Eur J Heart Fail 15:995–1002CrossRef Zarrinkoub R, Wettermark B, Wandell P, Mejhert M, Szulkin R, Ljunggren G, Kahan T (2013) The epidemiology of heart failure, based on data for 2.1 million inhabitants in Sweden. Eur J Heart Fail 15:995–1002CrossRef
Metadata
Title
Vitamin D deficiency was common in all patients at a Swedish primary care centre, but more so in patients born outside of Europe
Authors
Per Wändell
Sahar Ayoob
Lennart Mossberg
Anna Andreasson
Publication date
01-12-2018
Publisher
Springer Berlin Heidelberg
Published in
Journal of Public Health / Issue 6/2018
Print ISSN: 2198-1833
Electronic ISSN: 1613-2238
DOI
https://doi.org/10.1007/s10389-018-0910-z

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