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Esophagus
Published in: Esophagus 1/2017

01-01-2017 | Review Article

Diagnosis and treatment of eosinophilic esophagitis in Japan

Authors: Yoshikazu Kinoshita, Norihisa Ishimura, Tsuyoshi Mishiro, Shunji Ishihara, Kyoichi Adachi

Published in: Esophagus | Issue 1/2017

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Abstract

Patients in Japan affected by eosinophilic esophagitis (EoE), considered to be a dietary allergen related chronic esophageal disease, are slowly increasing. For diagnosis, careful assessments of atopic diathesis and symptoms, an endoscopic examination focusing on EoE characteristic findings, and histopathological examination of appropriate biopsy samples are important. When clinicopathological examination results suggest EoE, proton pump inhibitor (PPI) administration should be attempted to determine the response (PPI-responsive esophageal eosinophilia, PPI-REE). For PPI-refractory cases, oral topical glucocorticoid administration is the first therapeutic option, followed by systemic glucocorticoids as necessary. Evidence-based guidelines are currently under development in Japan for standardizing diagnosis and treatment.
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Metadata
Title
Diagnosis and treatment of eosinophilic esophagitis in Japan
Authors
Yoshikazu Kinoshita
Norihisa Ishimura
Tsuyoshi Mishiro
Shunji Ishihara
Kyoichi Adachi
Publication date
01-01-2017
Publisher
Springer Japan
Published in
Esophagus / Issue 1/2017
Print ISSN: 1612-9059
Electronic ISSN: 1612-9067
DOI
https://doi.org/10.1007/s10388-016-0550-8

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