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Japanese Journal of Ophthalmology
Published in: Japanese Journal of Ophthalmology 4/2019

01-07-2019 | Retinal Detachment | Clinical Investigation

Clinical factors contributing to postoperative aqueous flare intensity after 27-gauge pars plana vitrectomy for the primary rhegmatogenous retinal detachment

Authors: Akira Tetsumoto, Hisanori Imai, Keiko Otsuka, Wataru Matsumiya, Akiko Miki, Makoto Nakamura

Published in: Japanese Journal of Ophthalmology | Issue 4/2019

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Abstract

Purpose

To investigate the perioperative clinical factors, which contribute to the postsurgical aqueous flare intensity (AFI) following 27-gauge pars plana vitrectomy (27GPPV) for primary rhegmatogenous retinal detachment (RRD).

Study design

Retrospective clinical study.

Methods

We performed retrospective analyses of the medical records of 47 eyes of 47 patients with primary RRD who had undergone 27GPPV with a wide-angle viewing system. AFI was measured preoperatively and 1 week, 1 month, 3 months, 6 months, and 12 months after the surgery.

Results

AFI was significantly increased 1 week after the surgery (p<0.01) and then decreased overtime. At 6 months after surgery it was still statistically significantly higher than preoperative AFI (p=0.03). There was no statistical difference between preoperative AFI and that at 12 months following surgery. Multiple regression analyses revealed that the number of retinal photocoagulations and the performance of scleral indentation had significant positive correlation with AFI at 1 week, 1 month, 3 months, and 6 months, and at 1 month and 3 months after the surgery, respectively.

Conclusion

Intraoperative retinal photocoagulation and scleral indentation are probable causes of increased AFI after 27G PPV for RRD.
Literature
1.
Kobashi H, Takano M, Yanagita T, Shiratani T, Wang G, Hoshi K, et al. Scleral buckling and pars plana vitrectomy for rhegmatogenous retinal detachment: an analysis of 542 eyes. Curr Eye Res. 2014;39:204–11.CrossRefPubMed
2.
Miki D, Hida T, Hotta K, Shinoda K, Hirakata A. Comparison of scleral buckling and vitrectomy for retinal detachment resulting from flap tears in superior quadrants. Jpn J Ophthalmol. 2001;45:187–91.CrossRefPubMed
3.
Kadonosono K, Yamakawa T, Uchio E, Yanagi Y, Tamaki Y, Araie M. Comparison of visual function after epiretinal membrane removal by 20-gauge and 25-gauge vitrectomy. Am J Ophthalmol. 2006;142:513–5.CrossRefPubMed
4.
Yoon YH, Kim DS, Kim JG, Hwang JU. Sutureless vitreoretinal surgery using a new 25- gauge transconjunctival system. Ophthalmic Surg Lasers Imaging. 2006;37:12–9.CrossRefPubMed
5.
Park DH, Shin JP, Kim SY. Surgically induced astigmatism in combined phacoemulsification and vitrectomy: 23-gauge transconjunctival sutureless vitrectomy versus 20-gauge standard vitrectomy. Graefes Arch Clin Exp Ophthalmol. 2009;247:1331–7.CrossRefPubMed
6.
Galway G, Drury B, Cronin BG, Bourke RD. A comparison of induced astigmatism in 20- vs 25-gauge vitrectomy procedures. Eye (London). 2010;24:315–7.CrossRef
7.
Rizzo S, Genovesi-Ebert F, Murri S, Belting C, Vneto A, Cresti F, et al. 25-gauge, sutureless vitrectomy and standard 20-gauge pars plana vitrectomy in idiopathic epiretinal membrane surgery: a comparative pilot study. Graefes Arch Clin Exp Ophthalmol. 2006;244:472–9.CrossRefPubMed
8.
Falkner-Radler CI, Myung JS, Moussa S, Chan RV, Smretschnig E, Kiss S, et al. Trends in primary retinal detachment surgery: results of a Bicenter study. Retina. 2011;31:928–36.CrossRefPubMed
9.
Ho JD, Liou SW, Tsai CY, Tsai RJ, Lin HC. Trends and outcomes of treatment for primary rhegmatogenous retinal detachment: a 9-year nationwide population-based study. Eye (London). 2009;23:669–75.CrossRef
10.
Wong CW, Wong WL, Yeo IY, Loh BK, Wong DW, Onq SG, et al. Trends and factors related to outcomes for primary rhegmatogenous retinal detachment surgery in a large asian tertiary eye center. Retina. 2014;34:684–92.CrossRefPubMed
11.
12.
13.
Romano MR, Cennamo G, Ferrara M, Cennamo M, Cennamo G. Twenty-seven-gauge versus 25-gauge vitrectomy for primary rhegmatogenous retinal detachment. Retina. 2017;37:637–42.CrossRefPubMed
14.
15.
Yoon YH, Sheu SJ, Terasaki H. Primary vitrectomy in rhegmatogenous retinal detachment. In: Schachat AP, Wilkinson CP, Wiedemann P, editors. Ryan’s retina. Philadelphia, PA: Elsevier; 2018. p. 1933–42.
16.
Conart JB, Kurun S, Ameloot F, Tréchot F, Leroy B, Berrod JP. Validity of aqueous flare measurement in predicting proliferative vitreoretinopathy in patients with rhegmatogenous retinal detachment. Acta Ophthalmol. 2017;95:e278–83.CrossRefPubMed
17.
Mulder VC, Tode J, van Dijk EH, Purtskhvanidze K, Roider J, van Meurs JC, et al. Preoperative aqueous humour flare values do not predict proliferative vitreoretinopathy in patients with rhegmatogenous retinal detachment. Br J Ophthalmol. 2017;101:1285–9.CrossRefPubMed
18.
Mulder VC, van Dijk EHC, van Meurs IA, La Heij EC, van Meurs JC. Postoperative aqueous humour flare as a surrogate marker for proliferative vitreoretinopathy development. Acta Ophthalmol. 2018;96:192–6.CrossRefPubMed
19.
Hoshi S, Okamoto F, Hasegawa Y, Sugiura Y, Okamoto Y, Hiraoka T, et al. Time course of changes in aqueous flare intensity after vitrectomy for rhegmatogenous retinal detachment. Retina. 2012;32:1862–7.CrossRefPubMed
20.
21.
Inoue M, Tsukahara Y, Shirabe H, Yamamoto M. Disruption of the blood-aqueous barrier following retinal laser photocoagulation and cryopexy in pigmented rabbits. Ophthalmic Res. 2001;33:37–41.CrossRefPubMed
22.
Marshall J, Hamilton AM, Bird AC. Histopathology of ruby and argon laser lesions in monkey and human retina. A comparative study. Br J Ophthalmol. 1975;59:610–30.CrossRefPubMedPubMedCentral
23.
Yamada Y, Takamura Y, Matsumura T, Morioka M, Gozawa M, Inatani M. Posterior subtenon infusion of triamcinolone acetonide as adjunctive treatment to panretinal photocoagulation using pattern scan laser for diabetic retinopathy. Jpn J Ophthalmol. 2018;62:686–92.CrossRefPubMed
24.
Arimura S, Takamura Y, Miyake S, Gozawa M, Iwasaki K, Tomomatsu T, et al. The effect of triamcinolone acetonide or bevacizumab on the levels of proinflammatory cytokines after retinal laser photocoagulation in pigmented rabbits. Exp Eye Res. 2016;149:1–7.CrossRefPubMed
25.
Takamura Y, Shimura M, Katome T, Someya H, Sugimoto M, Hirano T, et al. Effect of intravitreal triamcinolone acetonide injection at the end of vitrectomy for vitreous haemorrhage related to proliferative diabetic retinopathy. Br J Ophthalmol. 2018;102:1351–7.CrossRefPubMedPubMedCentral
Metadata
Title
Clinical factors contributing to postoperative aqueous flare intensity after 27-gauge pars plana vitrectomy for the primary rhegmatogenous retinal detachment
Authors
Akira Tetsumoto
Hisanori Imai
Keiko Otsuka
Wataru Matsumiya
Akiko Miki
Makoto Nakamura
Publication date
01-07-2019
Publisher
Springer Japan
Published in
Japanese Journal of Ophthalmology / Issue 4/2019
Print ISSN: 0021-5155
Electronic ISSN: 1613-2246
DOI
https://doi.org/10.1007/s10384-019-00672-9

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