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Japanese Journal of Ophthalmology
Published in: Japanese Journal of Ophthalmology 6/2016

01-11-2016 | Clinical Investigation

Changes in chorioretinal blood flow velocity and cerebral blood flow after carotid endarterectomy

Authors: Hiroshi Enaida, Shinji Nagata, Atsunobu Takeda, Shintaro Nakao, Yasuhiro Ikeda, Tatsuro Ishibashi

Published in: Japanese Journal of Ophthalmology | Issue 6/2016

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Abstract

Purpose

To investigate the changes in chorioretinal blood flow velocity and cerebral blood after carotid endarterectomy (CEA).

Methods

Nine patients with moderate to severe internal carotid artery stenosis underwent CEA. Chorioretinal blood flow velocity was measured by laser speckle flowgraphy (LSFG), while cerebral blood flow (CBF) was measured by single-photon emission computed tomography (SPECT), on the affected side both before and after CEA. LSFG was evaluated in five areas to determine mean blur rate, while CBF was calculated from regional CBF and cerebrovascular reactivity (CVR), at the middle cerebral artery (MCA) region of each patient.

Results

Five cases showed an increase (mean 3.49 %, range −29.82 to 35.59 %) of average chorioretinal blood flow velocity using LSFG after CEA. A particularly averaged increase in chorioretinal blood flow was observed in the macular area compared with other areas. Similarly, there was an increase in CBF at rest (mean 11.46 %, range −14.51 to 74.14 %) observed using SPECT after surgery. Improvement of CVR was confirmed in four cases. All general and visual symptoms disappeared after CEA. Severe adverse effects, including hyperperfusion syndrome, were not observed in any cases.

Conclusions

LSFG may be useful for the analysis of chorioretinal blood flow changes after CEA.
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Metadata
Title
Changes in chorioretinal blood flow velocity and cerebral blood flow after carotid endarterectomy
Authors
Hiroshi Enaida
Shinji Nagata
Atsunobu Takeda
Shintaro Nakao
Yasuhiro Ikeda
Tatsuro Ishibashi
Publication date
01-11-2016
Publisher
Springer Japan
Published in
Japanese Journal of Ophthalmology / Issue 6/2016
Print ISSN: 0021-5155
Electronic ISSN: 1613-2246
DOI
https://doi.org/10.1007/s10384-016-0472-y

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