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Japanese Journal of Ophthalmology
Published in: Japanese Journal of Ophthalmology 4/2013

01-07-2013 | Clinical Investigation

Laser speckle flowgraphy for differentiating between nonarteritic ischemic optic neuropathy and anterior optic neuritis

Authors: Tomoyuki Maekubo, Hideki Chuman, Nobuhisa Nao-i

Published in: Japanese Journal of Ophthalmology | Issue 4/2013

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Abstract

Purpose

The aim of this study was to investigate the usefulness of laser speckle flowgraphy (LSFG) for the differentiation of acute nonarteritic ischemic optic neuropathy (NAION) from anterior optic neuritis (ON).

Methods

To investigate blood flow in the optic disc under normal conditions, NAION, and anterior ON, we compared the tissue blood flow of the right eye with that of the left eye in the control group, and that of the affected eye with that of the unaffected eye in the NAION and anterior ON groups.

Results

In the normal control group, the tissue blood flow did not significantly differ between the right and left eyes. In the NAION group, all 6 patients had decreased optic disc blood flow in the NAION eye when compared with the unaffected eye. By contrast, in the anterior ON group, all 6 patients had increased optic disc blood flow in the anterior ON eye when compared with the unaffected eye. In the NAION group, the mean blur rate (MBR) of the affected eyes was 29.5 % lower than that of the unaffected eyes. In the anterior ON group, the MBR of the affected eyes was 15.9 % higher than that of the unaffected eyes.

Conclusions

LSFG could be useful in differentiating between NAION and anterior ON. In addition, this imaging technique saves time and is noninvasive.
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Metadata
Title
Laser speckle flowgraphy for differentiating between nonarteritic ischemic optic neuropathy and anterior optic neuritis
Authors
Tomoyuki Maekubo
Hideki Chuman
Nobuhisa Nao-i
Publication date
01-07-2013
Publisher
Springer Japan
Published in
Japanese Journal of Ophthalmology / Issue 4/2013
Print ISSN: 0021-5155
Electronic ISSN: 1613-2246
DOI
https://doi.org/10.1007/s10384-013-0246-8

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