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Magnetic Resonance Materials in Physics, Biology and Medicine

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01-10-2020 | Magnetic Resonance Imaging | Research Article

Investigation of phase-contrast magnetic resonance imaging underestimation of turbulent flow through the aortic valve phantom: experimental and computational study using lattice Boltzmann method

Authors: Radek Fučík, Radek Galabov, Petr Pauš, Pavel Eichler, Jakub Klinkovský, Robert Straka, Jaroslav Tintěra, Radomír Chabiniok

Published in: Magnetic Resonance Materials in Physics, Biology and Medicine | Issue 5/2020

Abstract

Objective

The accuracy of phase-contrast magnetic resonance imaging (PC-MRI) measurement is investigated using a computational fluid dynamics (CFD) model with the objective to determine the magnitude of the flow underestimation due to turbulence behind a narrowed valve in a phantom experiment.

Materials and methods

An acrylic stationary flow phantom is used with three insertable plates mimicking aortic valvular stenoses of varying degrees. Positive and negative horizontal fluxes are measured at equidistant slices using standard PC-MRI sequences by 1.5T and 3T systems. The CFD model is based on the 3D lattice Boltzmann method (LBM). The experimental and simulated data are compared using the Bland-Altman-derived limits of agreement. Based on the LBM results, the turbulence is quantified and confronted with the level of flow underestimation.

Results

LBM gives comparable results to PC-MRI for valves up to moderate stenosis on both field strengths. The flow magnitude through a severely stenotic valve was underestimated due to signal void in the regions of turbulent flow behind the valve, consistently with the level of quantified turbulence intensity.

Discussion

Flow measured by PC-MRI is affected by noise and turbulence. LBM can simulate turbulent flow efficiently and accurately, it has therefore the potential to improve clinical interpretation of PC-MRI.

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Title: Investigation of phase-contrast magnetic resonance imaging underestimation of turbulent flow through the aortic valve phantom: experimental and computational study using lattice Boltzmann method
Authors: Radek Fučík
Radek Galabov
Petr Pauš
Pavel Eichler
Jakub Klinkovský
Robert Straka
Jaroslav Tintěra
Radomír Chabiniok
Publication date: 01-10-2020
Publisher: Springer International Publishing
Keywords: Magnetic Resonance Imaging
Magnetic Resonance Imaging
Aortic Valve Stenosis
Published in: Magnetic Resonance Materials in Physics, Biology and Medicine / Issue 5/2020
Print ISSN: 0968-5243
Electronic ISSN: 1352-8661
DOI: https://doi.org/10.1007/s10334-020-00837-5

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Investigation of phase-contrast magnetic resonance imaging underestimation of turbulent flow through the aortic valve phantom: experimental and computational study using lattice Boltzmann method

Abstract

Objective

Materials and methods

Results

Discussion

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Abstract

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Materials and methods

Results

Discussion

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