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Magnetic Resonance Materials in Physics, Biology and Medicine
Published in: Magnetic Resonance Materials in Physics, Biology and Medicine 1/2020

Open Access 01-02-2020 | Biomarkers | Review

Consensus-based technical recommendations for clinical translation of renal BOLD MRI

Authors: Octavia Bane, Iosif A. Mendichovszky, Bastien Milani, Ilona A. Dekkers, Jean-Francois Deux, Per Eckerbom, Nicolas Grenier, Michael E. Hall, Tsutomu Inoue, Christoffer Laustsen, Lilach O. Lerman, Chunlei Liu, Glen Morrell, Michael Pedersen, Menno Pruijm, Elizabeth A. Sadowski, Erdmann Seeliger, Kanishka Sharma, Harriet Thoeny, Peter Vermathen, Zhen J. Wang, Zbigniew Serafin, Jeff L. Zhang, Susan T. Francis, Steven Sourbron, Andreas Pohlmann, Sean B. Fain, Pottumarthi V. Prasad

Published in: Magnetic Resonance Materials in Physics, Biology and Medicine | Issue 1/2020

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Abstract

Harmonization of acquisition and analysis protocols is an important step in the validation of BOLD MRI as a renal biomarker. This harmonization initiative provides technical recommendations based on a consensus report with the aim to move towards standardized protocols that facilitate clinical translation and comparison of data across sites. We used a recently published systematic review paper, which included a detailed summary of renal BOLD MRI technical parameters and areas of investigation in its supplementary material, as the starting point in developing the survey questionnaires for seeking consensus. Survey data were collected via the Delphi consensus process from 24 researchers on renal BOLD MRI exam preparation, data acquisition, data analysis, and interpretation. Consensus was defined as ≥ 75% unanimity in response. Among 31 survey questions, 14 achieved consensus resolution, 12 showed clear respondent preference (65–74% agreement), and 5 showed equal (50/50%) split in opinion among respondents. Recommendations for subject preparation, data acquisition, processing and reporting are given based on the survey results and review of the literature. These technical recommendations are aimed towards increased inter-site harmonization, a first step towards standardization of renal BOLD MRI protocols across sites. We expect this to be an iterative process updated dynamically based on progress in the field.
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Metadata
Title
Consensus-based technical recommendations for clinical translation of renal BOLD MRI
Authors
Octavia Bane
Iosif A. Mendichovszky
Bastien Milani
Ilona A. Dekkers
Jean-Francois Deux
Per Eckerbom
Nicolas Grenier
Michael E. Hall
Tsutomu Inoue
Christoffer Laustsen
Lilach O. Lerman
Chunlei Liu
Glen Morrell
Michael Pedersen
Menno Pruijm
Elizabeth A. Sadowski
Erdmann Seeliger
Kanishka Sharma
Harriet Thoeny
Peter Vermathen
Zhen J. Wang
Zbigniew Serafin
Jeff L. Zhang
Susan T. Francis
Steven Sourbron
Andreas Pohlmann
Sean B. Fain
Pottumarthi V. Prasad
Publication date
01-02-2020
Publisher
Springer International Publishing
Keyword
Biomarkers
Published in
Magnetic Resonance Materials in Physics, Biology and Medicine / Issue 1/2020
Print ISSN: 0968-5243
Electronic ISSN: 1352-8661
DOI
https://doi.org/10.1007/s10334-019-00802-x

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