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Published in: Odontology 3/2019

01-07-2019 | Antibiotic | Original Article

Aerobic and anaerobic microorganisms and antibiotic sensitivity of odontogenic maxillofacial infections

Authors: Emmanuel López-González, Marlen Vitales-Noyola, Ana María González-Amaro, Verónica Méndez-González, Antonio Hidalgo-Hurtado, Rosaura Rodríguez-Flores, Amaury Pozos-Guillén

Published in: Odontology | Issue 3/2019

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Abstract

This study aimed to identify the aerobic and anaerobic causal microorganisms of odontogenic infections and their antibiotic sensitivity. Purulent exudates were taken from patients with odontogenic infections by transdermal puncture, and aerobic and anaerobic microorganisms were identified using biochemical tests. Susceptibility to antibiotics was tested using the Kirby-Bauer method; the inhibition halos were measured according to NCCLS, and based on the results, the microorganisms were classified as susceptible, intermediate or resistant to each antibiotic. Frequencies of species and percentages of resistance were calculated. The microorganisms associated with odontogenic infections were principally anaerobic (65.3% anaerobic vs. 35.7% aerobic), and the susceptibility to antibiotics was higher in anaerobic than in aerobic microorganisms. The majority of isolated microorganisms (82%) showed susceptibility to amoxicillin/clavulanic acid. The causal agents of odontogenic infections were anaerobic microorganisms, which exhibited high resistance to antibiotics.
Literature
1.
go back to reference Taub D, Yampolsky A, Diecidue R, Gold L. Controversies in the management of oral and maxillofacial infections. Oral Maxillofac Surg Clin North Am. 2017;4:465–73.CrossRef Taub D, Yampolsky A, Diecidue R, Gold L. Controversies in the management of oral and maxillofacial infections. Oral Maxillofac Surg Clin North Am. 2017;4:465–73.CrossRef
2.
go back to reference McDonald C, Hennedige A, Henry A, et al. Management of cervicofacial infections: a survey of current practice in maxillofacial units in the UK. Br J Oral Maxillofac Surg. 2017;9:940–5.CrossRef McDonald C, Hennedige A, Henry A, et al. Management of cervicofacial infections: a survey of current practice in maxillofacial units in the UK. Br J Oral Maxillofac Surg. 2017;9:940–5.CrossRef
3.
go back to reference The Japanese Association for Infectious Disease/Japanese Society of Chemotherapy, The JAID/JSC Committee for Developing Treatment Guide and Guidelines for Clinical Management of Infectious Disease, Odontogenic Infection Working Group. The 2016 JAID/JSC guidelines for clinical management of infectious disease-Odontogenic infections. J Infect Chemother. 2018;24:320–4.CrossRef The Japanese Association for Infectious Disease/Japanese Society of Chemotherapy, The JAID/JSC Committee for Developing Treatment Guide and Guidelines for Clinical Management of Infectious Disease, Odontogenic Infection Working Group. The 2016 JAID/JSC guidelines for clinical management of infectious disease-Odontogenic infections. J Infect Chemother. 2018;24:320–4.CrossRef
4.
go back to reference Bahl R, Sandhu S, Singh K, Sahai N, Gupta M. Odontogenic infections: microbiology and management. Contemp Clin Dent. 2014;3:307–11.CrossRef Bahl R, Sandhu S, Singh K, Sahai N, Gupta M. Odontogenic infections: microbiology and management. Contemp Clin Dent. 2014;3:307–11.CrossRef
5.
go back to reference Heim N, Faron A, Wiedemeyer V, Reich R, Martini M. Microbiology and antibiotic sensitivity of head and neck space infections of odontogenic origin. Differences in inpatient and outpatient management. J Craniomaxillofac Surg. 2017;45:1731–5.CrossRefPubMed Heim N, Faron A, Wiedemeyer V, Reich R, Martini M. Microbiology and antibiotic sensitivity of head and neck space infections of odontogenic origin. Differences in inpatient and outpatient management. J Craniomaxillofac Surg. 2017;45:1731–5.CrossRefPubMed
6.
go back to reference Tung-Yiu W, Jehn-Shyun H, Ching-Hung C, Hung-An C. Cervical necrotizing fasciitis of odontogenic origin: a report of 11 cases. J Oral Maxillofac Surg. 2000;12:1347–52. discussion 1353.CrossRef Tung-Yiu W, Jehn-Shyun H, Ching-Hung C, Hung-An C. Cervical necrotizing fasciitis of odontogenic origin: a report of 11 cases. J Oral Maxillofac Surg. 2000;12:1347–52. discussion 1353.CrossRef
8.
go back to reference Arora N, Juneja R, Meher R. Complication of an odontogenic infection to an orbital abscess: the role of a medical fraudster (“Quack”). Iran J Otorhinolaryngol. 2018;30:181–4.PubMedPubMedCentral Arora N, Juneja R, Meher R. Complication of an odontogenic infection to an orbital abscess: the role of a medical fraudster (“Quack”). Iran J Otorhinolaryngol. 2018;30:181–4.PubMedPubMedCentral
9.
go back to reference Farmahan S, Tuopar D, Ameerally PJ, Kotecha R, Sisodia B. Microbiological examination and antibiotic sensitivity of infections in the head and neck. Has anything changed? Br J Oral Maxillofac Surg. 2014;52:632–5.CrossRefPubMed Farmahan S, Tuopar D, Ameerally PJ, Kotecha R, Sisodia B. Microbiological examination and antibiotic sensitivity of infections in the head and neck. Has anything changed? Br J Oral Maxillofac Surg. 2014;52:632–5.CrossRefPubMed
10.
go back to reference Chunduri NS, Madasu K, Goteki VR, Karpe T, Reddy H. Evaluation of bacterial spectrum of orofacial infections and their antibiotic susceptibility. Ann Maxillofac Surg. 2012;2:46–50.CrossRefPubMedPubMedCentral Chunduri NS, Madasu K, Goteki VR, Karpe T, Reddy H. Evaluation of bacterial spectrum of orofacial infections and their antibiotic susceptibility. Ann Maxillofac Surg. 2012;2:46–50.CrossRefPubMedPubMedCentral
11.
go back to reference Walia IS, Borle RM, Mehendiratta D, Yadav AO. Microbiology and antibiotic sensitivity of head and neck space infections of odontogenic origin. J Maxillofac Oral Surg. 2014;1:16–21.CrossRef Walia IS, Borle RM, Mehendiratta D, Yadav AO. Microbiology and antibiotic sensitivity of head and neck space infections of odontogenic origin. J Maxillofac Oral Surg. 2014;1:16–21.CrossRef
12.
go back to reference Tüzüner Öncül AM, Uzunoğlu E, Karahan ZC, Aksoy AM, Kişnişci R, Karaahmetoğlu Ö. Detecting gram-positive anaerobic cocci directly from the clinical samples by multiplex polymerase chain reaction in odontogenic infections. J Oral Maxillofac Surg. 2015;73:259–66.CrossRefPubMed Tüzüner Öncül AM, Uzunoğlu E, Karahan ZC, Aksoy AM, Kişnişci R, Karaahmetoğlu Ö. Detecting gram-positive anaerobic cocci directly from the clinical samples by multiplex polymerase chain reaction in odontogenic infections. J Oral Maxillofac Surg. 2015;73:259–66.CrossRefPubMed
13.
14.
go back to reference Performed standards for antimicrobial disk susceptibility tests. National Committee for Clinical Laboratory Standards. Approved standard M2-A8. 8th ed. Pa: NCCLS, Wayne; 2003. Performed standards for antimicrobial disk susceptibility tests. National Committee for Clinical Laboratory Standards. Approved standard M2-A8. 8th ed. Pa: NCCLS, Wayne; 2003.
15.
go back to reference Babu VR, Ikkurthi S, Perisetty DK, Babu KAS, Rasool M, Shaik S. A prospective comparison of computed tomography and magnetic resonance imaging as a diagnostic tool for maxillofacial space infections. J Int Soc Prev Community Dent. 2018;8:343–8.CrossRefPubMedPubMedCentral Babu VR, Ikkurthi S, Perisetty DK, Babu KAS, Rasool M, Shaik S. A prospective comparison of computed tomography and magnetic resonance imaging as a diagnostic tool for maxillofacial space infections. J Int Soc Prev Community Dent. 2018;8:343–8.CrossRefPubMedPubMedCentral
16.
go back to reference Nadig K, Taylor NG. Management of odontogenic infection at a district general hospital. Br Dent J. 2018;224:962–6.CrossRefPubMed Nadig K, Taylor NG. Management of odontogenic infection at a district general hospital. Br Dent J. 2018;224:962–6.CrossRefPubMed
17.
go back to reference Bakathir AA, Moos KF, Ayoub AF, Bagg J. Factors contributing to the spread of odontogenic infections: a prospective pilot study. Sultan Qaboos Univ Med J. 2009;9:296–304.PubMedPubMedCentral Bakathir AA, Moos KF, Ayoub AF, Bagg J. Factors contributing to the spread of odontogenic infections: a prospective pilot study. Sultan Qaboos Univ Med J. 2009;9:296–304.PubMedPubMedCentral
18.
go back to reference Chang JS, Yoo KH, Yoon SH, et al. Odontogenic infection involving the secondary fascial space in diabetic and non-diabetic patients: a clinical comparative study. J Korean Assoc Oral Maxillofac Surg. 2013;39:175–81.CrossRefPubMedPubMedCentral Chang JS, Yoo KH, Yoon SH, et al. Odontogenic infection involving the secondary fascial space in diabetic and non-diabetic patients: a clinical comparative study. J Korean Assoc Oral Maxillofac Surg. 2013;39:175–81.CrossRefPubMedPubMedCentral
19.
go back to reference Lin RH, Huang CC, Tsou YA, et al. Correlation between imaging characteristics and microbiology in patients with deep neck infections: a retrospective review of one hundred sixty-one cases. Surg Infect (Larchmt). 2014;15:794–9.CrossRef Lin RH, Huang CC, Tsou YA, et al. Correlation between imaging characteristics and microbiology in patients with deep neck infections: a retrospective review of one hundred sixty-one cases. Surg Infect (Larchmt). 2014;15:794–9.CrossRef
20.
go back to reference Shakya N, Sharma D, Newaskar V, Agrawal D, Shrivastava S, Yadav R. Epidemiology, microbiology and antibiotic sensitivity of odontogenic space infections in Central India. J Maxillofac Oral Surg. 2018;3:324–31.CrossRef Shakya N, Sharma D, Newaskar V, Agrawal D, Shrivastava S, Yadav R. Epidemiology, microbiology and antibiotic sensitivity of odontogenic space infections in Central India. J Maxillofac Oral Surg. 2018;3:324–31.CrossRef
22.
go back to reference Bhagania M, Youseff W, Mehra P, Figueroa R. Treatment of odontogenic infections: an analysis of two antibiotic regimens. J Oral Biol Craniofac Res. 2018;8:78–81.CrossRefPubMedPubMedCentral Bhagania M, Youseff W, Mehra P, Figueroa R. Treatment of odontogenic infections: an analysis of two antibiotic regimens. J Oral Biol Craniofac Res. 2018;8:78–81.CrossRefPubMedPubMedCentral
23.
go back to reference Mathew GC, Ranganathan LK, Gandhi S, et al. Odontogenic maxillofacial space infections at a tertiary care center in North India: a five-year retrospective study. Int J Infect Dis. 2012;16:e296–302.CrossRefPubMed Mathew GC, Ranganathan LK, Gandhi S, et al. Odontogenic maxillofacial space infections at a tertiary care center in North India: a five-year retrospective study. Int J Infect Dis. 2012;16:e296–302.CrossRefPubMed
24.
go back to reference Shah A, Ramola V, Nautiyal V. Aerobic microbiology and culture sensitivity of head and neck space infection of odontogenic origin. Natl J Maxillofac Surg. 2016;7:56–61.CrossRefPubMedPubMedCentral Shah A, Ramola V, Nautiyal V. Aerobic microbiology and culture sensitivity of head and neck space infection of odontogenic origin. Natl J Maxillofac Surg. 2016;7:56–61.CrossRefPubMedPubMedCentral
25.
go back to reference Hyun SY, Oh HK, Ryu JY, Kim JJ, Cho JY, Kim HM. Closed suction drainage for deep neck infections. J Craniomaxillofac Surg. 2014;42:751–6.CrossRefPubMed Hyun SY, Oh HK, Ryu JY, Kim JJ, Cho JY, Kim HM. Closed suction drainage for deep neck infections. J Craniomaxillofac Surg. 2014;42:751–6.CrossRefPubMed
26.
go back to reference Fating NS, Saikrishna D, Vijay Kumar GS, Shetty SK, Raghavendra Rao M. Detection of bacterial flora in orofacial space infections and their antibiotic sensitivity profile. J Maxillofac Oral Surg. 2014;13:525–32.CrossRefPubMed Fating NS, Saikrishna D, Vijay Kumar GS, Shetty SK, Raghavendra Rao M. Detection of bacterial flora in orofacial space infections and their antibiotic sensitivity profile. J Maxillofac Oral Surg. 2014;13:525–32.CrossRefPubMed
27.
go back to reference Gómez-Arámbula H, Hidalgo-Hurtado A, Rodríguez-Flores R, González-Amaro AM, Garrocho-Rangel A, Pozos-Guillén A. Moxifloxacin versus clindamycin/ceftriaxone in the management of odontogenic maxillofacial infectious processes: a preliminary, intrahospital, controlled clinical trial. J Clin Exp Dent. 2015;7:e634–9.PubMedPubMedCentral Gómez-Arámbula H, Hidalgo-Hurtado A, Rodríguez-Flores R, González-Amaro AM, Garrocho-Rangel A, Pozos-Guillén A. Moxifloxacin versus clindamycin/ceftriaxone in the management of odontogenic maxillofacial infectious processes: a preliminary, intrahospital, controlled clinical trial. J Clin Exp Dent. 2015;7:e634–9.PubMedPubMedCentral
28.
go back to reference Farmahan S, Tuopar D, Ameerally PJ. A study to investigate changes in the microbiology and antibiotic sensitivity of head and neck space infections. Surgeon. 2015;13:316–20.CrossRefPubMed Farmahan S, Tuopar D, Ameerally PJ. A study to investigate changes in the microbiology and antibiotic sensitivity of head and neck space infections. Surgeon. 2015;13:316–20.CrossRefPubMed
29.
go back to reference Davis K, Gill D, Mouton CP, Southerland J, Halpern L. An unusual odontogenic infection due to clostridium subterminale in an immunocompetent patient: a case report and review of the literature. IDCases. 2018;12:34–40.CrossRefPubMedPubMedCentral Davis K, Gill D, Mouton CP, Southerland J, Halpern L. An unusual odontogenic infection due to clostridium subterminale in an immunocompetent patient: a case report and review of the literature. IDCases. 2018;12:34–40.CrossRefPubMedPubMedCentral
30.
go back to reference Tancawan AL, Pato MN, Abidin KZ, et al. Amoxicillin/clavulanic acid for the treatment of odontogenic infections: a randomised study comparing efficacy and tolerability versus Clindamycin. Int J Dent. 2015;2015:472470.CrossRefPubMedPubMedCentral Tancawan AL, Pato MN, Abidin KZ, et al. Amoxicillin/clavulanic acid for the treatment of odontogenic infections: a randomised study comparing efficacy and tolerability versus Clindamycin. Int J Dent. 2015;2015:472470.CrossRefPubMedPubMedCentral
31.
go back to reference Dar-Odeh NS, Abu-Hammad OA, Al-Omiri MK, Khraisat AS, Shehabi AA. Antibiotic prescribing practices by dentists: a review. Ther Clin Risk Manag. 2010;6:301–6.CrossRefPubMedPubMedCentral Dar-Odeh NS, Abu-Hammad OA, Al-Omiri MK, Khraisat AS, Shehabi AA. Antibiotic prescribing practices by dentists: a review. Ther Clin Risk Manag. 2010;6:301–6.CrossRefPubMedPubMedCentral
32.
go back to reference Sweeney LC, Dave J, Chambers PA, Heritage J. Antibiotic resistance in general dental practice—a cause for concern? J Antimicrob Chemother. 2004;53:567–76.CrossRefPubMed Sweeney LC, Dave J, Chambers PA, Heritage J. Antibiotic resistance in general dental practice—a cause for concern? J Antimicrob Chemother. 2004;53:567–76.CrossRefPubMed
33.
go back to reference Svensäter G, Bergenholtz G. Biofilm in endodontic infections. Endodontic Topics. 2004;9:27–36.CrossRef Svensäter G, Bergenholtz G. Biofilm in endodontic infections. Endodontic Topics. 2004;9:27–36.CrossRef
Metadata
Title
Aerobic and anaerobic microorganisms and antibiotic sensitivity of odontogenic maxillofacial infections
Authors
Emmanuel López-González
Marlen Vitales-Noyola
Ana María González-Amaro
Verónica Méndez-González
Antonio Hidalgo-Hurtado
Rosaura Rodríguez-Flores
Amaury Pozos-Guillén
Publication date
01-07-2019
Publisher
Springer Japan
Published in
Odontology / Issue 3/2019
Print ISSN: 1618-1247
Electronic ISSN: 1618-1255
DOI
https://doi.org/10.1007/s10266-019-00414-w

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