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Open Access 01-10-2010 | Original

Are Cox-2 drugs the second line option in indomethacin responsive headaches?

Authors: Jesús Porta-Etessam, Marialuz Cuadrado, Octavio Rodríguez-Gómez, Sara García-Ptacek, Cristina Valencia

Published in: The Journal of Headache and Pain | Issue 5/2010

Abstract

Paroxysmal hemicrania and hemicrania continua are both indomethacin-responsive headaches. Although indomethacin use to be well tolerated, some patients developed gastrointestinal side effects. We report four cases of hemicrania continua and a patient suffering chronic paroxysmal hemicrania completely responsive to celecoxib. In our experience celecoxib is a good option treatment for patients suffering from hemicrania continua or chronic paroxysmal hemicranea that presents indomethacin adverse effects.

Pareja JA, Caminero AB, Franco E, Casado JL, Pascual J, Sànchez del Rìo M (2001) Dose, efficacy and tolerability of longterm indomethacin treatment of chronic paroxysmal hemicrania and hemicrania continua. Cephalalgia 21:906–910, 1:STN:280:DC%2BD387nvF2jtQ%3D%3D, 10.1046/j.1468-2982.2001.00287.xPubMedCrossRef

Prasit P, Wang Z, Brideau C et al (1999) The discovery of rofecoxib, [MK 966, Vioxx, 4-(4 k-methylsulfonylphenyl)-3-phenyl-2 (5H)-furanone], an orally active cyclooxygenase-2-inhibitor. Bioorg Med Chem Lett 5(9):1773–1778, 10.1016/S0960-894X(99)00288-7CrossRef

Wheeler SD (2000) Rofecoxib-responsive hemicrania continua. Headache 40:436–437, 10.1046/j.1526-4610.2000.00078.xCrossRef

Peres MFP, Zukerman E (2000) Hemicrania continua responsive to rofecoxib. Cephalalgia 20:130–131, 1:STN:280:DC%2BD3M%2FlsFGmuw%3D%3D, 10.1046/j.1468-2982.2000.00029.xPubMedCrossRef

Piovesan EJ, Zukerman E, Kowacs PA, Werneck LC (2002) COX-2 inhibitor for the treatment of idiopathic stabbing headache secondary to cerebrovascular diseases. Cephalagia 22:197–200, 1:STN:280:DC%2BD38zht1elsQ%3D%3D, 10.1046/j.1468-2982.2002.00346.xCrossRef

Lisotto C, Maggioni F, Mainardi F, Zanchin G (2003) Rofecoxib for the treatment of chronic paroxysmal hemicrania. Cephalalgia 23:318–320, 1:STN:280:DC%2BD3s7pslWguw%3D%3D, 10.1046/j.1468-2982.2003.00500.xPubMedCrossRef

Siow HC (2004) Seasonal episodic paroxysmal hemicrania responding to cyclooxygenase-2 inhibitors. Cephalalgia 24:414–415, 1:STN:280:DC%2BD2c3kt12ksw%3D%3D, 10.1111/j.1468-2982.2003.00695.xPubMedCrossRef

Peres MF, Silberstein SD (2002) Hemicrania continua responds to cyclo-oxygenase 2 inhibitors. Headache 42:530–531, 10.1046/j.1526-4610.2002.02131.xPubMedCrossRef

O’Connor MB, Murphy E, Phelan MJ, Regan MJ (2008) Primary stabbing headache can be responsive to etoricoxib, a selective COX-2 inhibitor. Eur J Neurol 15:e1, 10.1111/j.1468-1331.2007.01962.xPubMedCrossRef

10.

O’Connor MB, Murphy E, Phelan MJ, Regan MJ (2007) The use of etoricoxib to treat an idiopathic stabbing headache: a case report. J Med Case Reports 1:100, 10.1186/1752-1947-1-100PubMedCentralCrossRef

11.

Ferrante E, Rossi P, Tassorelli C, Lisotto C, Nappi G (2010) Focus on therapy of primary stabbing headache. J Headache Pain 11:157–160, 1:CAS:528:DC%2BC3cXjtlalsrs%3D, 10.1007/s10194-010-0189-0PubMedCentralPubMedCrossRef

12.

Hannerz J, Ericson K, Bergstrand G (1987) Chronic paroxysmal hemicrania: orbital phlebography and steroid treatment. A case report. Cephalalgia 7:189–192, 1:STN:280:DyaL1c%2Fgt1eisA%3D%3D, 10.1046/j.1468-2982.1987.0703189.xPubMedCrossRef

13.

Wamer JS, Wamil AW, McLean MJ (1994) Acetazolamide for the treatment of chronic paroxysmal hemicrania. Headache 34:597–599, 10.1111/j.1526-4610.1994.hed3410597.xCrossRef

14.

Coria F, Claveria LE, Jimenez-Jimenez FJ, de Seijas EV (1992) Episodic paroxysmal hemicrania responsive to calcium channel blockers. J Neurol Neurosurg Psychiatry 55:166, 1:STN:280:DyaK387ms1yntQ%3D%3D, 10.1136/jnnp.55.2.166PubMedCentralPubMedCrossRef

15.

Evers S, Husstedt IW (1996) Alternatives in drug treatment of chronic paroxysmal hemicrania. Headache 36:429–432, 1:STN:280:DyaK28znslKmsQ%3D%3D, 10.1046/j.1526-4610.1996.3607429.xPubMedCrossRef

16.

Sjaastad O, Antonaci F (1995) A piroxicam derivative partly effective in chronic paroxysmal hemicrania and hemicrania continua. Headache 35:549–550, 1:STN:280:DyaK28%2FosVCrtA%3D%3D, 10.1111/j.1526-4610.1995.hed3509549.xPubMedCrossRef

Title: Are Cox-2 drugs the second line option in indomethacin responsive headaches?
Authors: Jesús Porta-Etessam
Marialuz Cuadrado
Octavio Rodríguez-Gómez
Sara García-Ptacek
Cristina Valencia
Publication date: 01-10-2010
Publisher: Springer Milan
Published in: The Journal of Headache and Pain / Issue 5/2010
Print ISSN: 1129-2369
Electronic ISSN: 1129-2377
DOI: https://doi.org/10.1007/s10194-010-0225-0

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Are Cox-2 drugs the second line option in indomethacin responsive headaches?

Abstract

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