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Clinical and Experimental Nephrology
Published in: Clinical and Experimental Nephrology 5/2019

Open Access 01-05-2019 | Budesonide | Invited review article

New strategies and perspectives on managing IgA nephropathy

Published in: Clinical and Experimental Nephrology | Issue 5/2019

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Abstract

IgA nephropathy is an inflammatory renal disease characterised by the deposition of IgA in the glomerular mesangium and is the most commonly reported primary glomerulonephritis worldwide. Thirty to forty percent of patients with the disease develop progressive renal function decline, requiring renal replacement therapy within two decades of diagnosis. Despite this, accurate individual risk stratification at diagnosis and predicting treatment response remains a challenge. Furthermore, there are currently no disease specific treatments currently licensed to treat the condition due to long standing challenges in the nature and prevalence of the disease. Despite this, there have been exciting recent advances in the field that may represent paradigm shifts in the way IgA nephropathy is managed in the near future. In this review, we explore the evidence base informing current approaches to management and explore new strategies and future directions in the diagnosis and management of IgA nephropathy.
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Metadata
Title
New strategies and perspectives on managing IgA nephropathy
Publication date
01-05-2019
Keyword
Budesonide
Published in
Clinical and Experimental Nephrology / Issue 5/2019
Print ISSN: 1342-1751
Electronic ISSN: 1437-7799
DOI
https://doi.org/10.1007/s10157-019-01700-1

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