Published in:
Open Access
01-12-2016 | Guideline
Clinical practice guideline for drug-induced kidney injury in Japan 2016: digest version
Authors:
Joichi Usui, Kunihiro Yamagata, Eri Imai, Hiroshi Okuyama, Hiroshi Kajiyama, Hiroshi Kanamori, Shuzo Kaneko, Emiko Kono, Yukinao Sakai, Norihiko Sakai, Yuichi Sakamaki, Yoshinori Taniguchi, Kentaro Nakai, Hiroki Nishiwaki, Sumio Hirata, Hideki Yamaya, Shuichi Tsuruoka, Yoshio Terada, Hitoshi Yokoyama, Takashi Wada, Ichiei Narita
Published in:
Clinical and Experimental Nephrology
|
Issue 6/2016
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Excerpt
Approximately one in eight adults has chronic kidney disease (CKD) in Japan, and the prevalence rate is expected to rise steeply due to the aging of the population in this country. In patients with CKD, quite a few medications require the dosage reduction or discontinuation because of their reduced urinary excretion and the increased risk of further renal impairment. Therefore, CKD patients are often treated by insufficient amounts of the medications, even though they may suffer from various complications. Moreover, it is empirically known that drug-induced kidney injury (DKI) accelerates the progression of renal failure, while it is not superficially ranked as a primary cause of kidney disease. …
