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01-08-2016 | Guideline

Clinical guides for atypical hemolytic uremic syndrome in Japan

Authors: Hideki Kato, Masaomi Nangaku, Hiroshi Hataya, Toshihiro Sawai, Akira Ashida, Rika Fujimaru, Yoshihiko Hidaka, Shinya Kaname, Shoichi Maruyama, Takashi Yasuda, Yoko Yoshida, Shuichi Ito, Motoshi Hattori, Yoshitaka Miyakawa, Yoshihiro Fujimura, Hirokazu Okada, Shoji Kagami, The Joint Committee for the Revision of Clinical Guides of Atypical Hemolytic Uremic Syndrome in Japan

Published in: Clinical and Experimental Nephrology | Issue 4/2016

Abstract

Atypical hemolytic uremic syndrome (aHUS) is a rare disease characterized by the triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury. In 2013, we developed diagnostic criteria to enable early diagnosis and timely initiation of appropriate treatment for aHUS. Recent clinical and molecular findings have resulted in several proposed classifications and definitions of thrombotic microangiopathy and aHUS. Based on recent advances in this field and the emerging international consensus to exclude secondary TMAs from the definition of aHUS, we have redefined aHUS and proposed diagnostic algorithms, differential diagnosis, and therapeutic strategies for aHUS.

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Title: Clinical guides for atypical hemolytic uremic syndrome in Japan
Authors: Hideki Kato
Masaomi Nangaku
Hiroshi Hataya
Toshihiro Sawai
Akira Ashida
Rika Fujimaru
Yoshihiko Hidaka
Shinya Kaname
Shoichi Maruyama
Takashi Yasuda
Yoko Yoshida
Shuichi Ito
Motoshi Hattori
Yoshitaka Miyakawa
Yoshihiro Fujimura
Hirokazu Okada
Shoji Kagami
The Joint Committee for the Revision of Clinical Guides of Atypical Hemolytic Uremic Syndrome in Japan
Publication date: 01-08-2016
Publisher: Springer Japan
Published in: Clinical and Experimental Nephrology / Issue 4/2016
Print ISSN: 1342-1751
Electronic ISSN: 1437-7799
DOI: https://doi.org/10.1007/s10157-016-1276-6

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