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Published in: Clinical and Experimental Nephrology 5/2011

01-10-2011 | Original Article

Nephrologist care for 12 months or more increases hemodialysis initiation with permanent vascular access

Authors: Daijo Inaguma, Ryoichi Ando, Masato Ikeda, Nobuhiko Joki, Fumihiko Koiwa, Yasuhiro Komatsu, Toshihumi Sakaguchi, Toshio Shinoda, Toshihiko Yamaka, Takashi Shigematsu

Published in: Clinical and Experimental Nephrology | Issue 5/2011

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Abstract

Background

The objective of this study was to evaluate the effect of early referral (ER) to nephrologists on the type of vascular access (VA) available for use at the time of initiation of maintenance hemodialysis (HD). In patients who have been followed by nephrologists for less than 3 months, management before the initiation of HD is often insufficient and urgent initiation of HD is often necessary; therefore, patients in this study were limited to those who had been followed for at least 3 months by nephrologists.

Methods

Nine hundred and forty patients at 9 institutions affiliated to our study group were enrolled in this retrospective observational study.
We defined patients followed up by nephrologists for at least 12 months as the early referral (ER) group and those followed for between 3 and 12 months as the late referral (LR) group. The type of VA available for use at the initiation of maintenance HD was compared between the groups.

Results

Early referral was found to be significantly associated with the availability of a permanent VA, which included an arteriovenous fistula or arteriovenous graft, at the time of initiation of HD (odds ratio [OR] 1.705; P = 0.001). Multivariate analysis also revealed ER to be significantly associated with the availability of a permanent VA (OR 1.509; P = 0.023).

Conclusion

Early referral was shown to be advantageous for increasing the likelihood of availability of a permanent VA, even after patients who had been followed up for less than 3 months by nephrologists were excluded.
Literature
1.
go back to reference Chen SC, Hwang SJ, Tsai JC, Liu WC, Hwang SC, Chou MC, et al. Early nephrology referral is associated with prolonged survival in hemodialysis patients even after exclusion of lead-time bias. Am J Med Sci. 2010;339:123–6.CrossRefPubMed Chen SC, Hwang SJ, Tsai JC, Liu WC, Hwang SC, Chou MC, et al. Early nephrology referral is associated with prolonged survival in hemodialysis patients even after exclusion of lead-time bias. Am J Med Sci. 2010;339:123–6.CrossRefPubMed
2.
go back to reference Arora P, Obrador GT, Ruthazer R, Kausz AT, Meyer KB, Jenuleson CS, et al. Prevalence, predictors, and consequences of late nephrology referral at a tertiary care center. J Am Soc Nephrol. 1999;10:1281–6.PubMed Arora P, Obrador GT, Ruthazer R, Kausz AT, Meyer KB, Jenuleson CS, et al. Prevalence, predictors, and consequences of late nephrology referral at a tertiary care center. J Am Soc Nephrol. 1999;10:1281–6.PubMed
3.
go back to reference Huisman RM. The deadly risk of late referral. Nephrol Dial Transpl. 2004;19:2175–80.CrossRef Huisman RM. The deadly risk of late referral. Nephrol Dial Transpl. 2004;19:2175–80.CrossRef
4.
go back to reference Lin CL, Chuang FR, Wu CF, Yang CT. Early referral as an independent predictor of clinical outcome in end-stage renal disease on hemodialysis and continuous ambulatory peritoneal dialysis. Ren Fail. 2004;26:531–7.CrossRefPubMed Lin CL, Chuang FR, Wu CF, Yang CT. Early referral as an independent predictor of clinical outcome in end-stage renal disease on hemodialysis and continuous ambulatory peritoneal dialysis. Ren Fail. 2004;26:531–7.CrossRefPubMed
5.
go back to reference Winkelmayer WC, Owen WF Jr, Levin R, Avorn J. A propensity analysis of late versus early nephrologist referral and mortality on dialysis. J Am Soc Nephrol. 2003;14:486–92.CrossRefPubMed Winkelmayer WC, Owen WF Jr, Levin R, Avorn J. A propensity analysis of late versus early nephrologist referral and mortality on dialysis. J Am Soc Nephrol. 2003;14:486–92.CrossRefPubMed
6.
go back to reference Chen SC, Hwang SJ, Tsai JC, Liu WC, Hwang SC, Chou MC, et al. Early nephrology referral is associated with prolonged survival in hemodialysis patients even after exclusion of lead-time bias. Am J Med Sci. 2010;339:123–6.CrossRefPubMed Chen SC, Hwang SJ, Tsai JC, Liu WC, Hwang SC, Chou MC, et al. Early nephrology referral is associated with prolonged survival in hemodialysis patients even after exclusion of lead-time bias. Am J Med Sci. 2010;339:123–6.CrossRefPubMed
7.
go back to reference Astor BC, Eustace JA, Powe NR, Klaq MJ, Sadler JH, Fink NE, et al. Timing of nephrologist referral and arteriovenous access use: the CHOICE Study. Am J Kidney Dis. 2001;38:494–501.CrossRefPubMed Astor BC, Eustace JA, Powe NR, Klaq MJ, Sadler JH, Fink NE, et al. Timing of nephrologist referral and arteriovenous access use: the CHOICE Study. Am J Kidney Dis. 2001;38:494–501.CrossRefPubMed
8.
go back to reference Ethier J, Mendelssohn DC, Elder SJ, Hasegawa T, Akizawa T, Akiba T, et al. Vascular access use and outcomes: an international perspective from the dialysis outcomes and practice patterns study. Nephrol Dial Transpl. 2008;23:3219–26.CrossRef Ethier J, Mendelssohn DC, Elder SJ, Hasegawa T, Akizawa T, Akiba T, et al. Vascular access use and outcomes: an international perspective from the dialysis outcomes and practice patterns study. Nephrol Dial Transpl. 2008;23:3219–26.CrossRef
9.
go back to reference Roderick P, Jones C, Drey N, Blakeley S, Webster P, Goddard J, et al. Late referral for end-stage renal disease: a region-wide survey in the south west of England. Nephrol Dial Transpl. 2002;17:1252–9.CrossRef Roderick P, Jones C, Drey N, Blakeley S, Webster P, Goddard J, et al. Late referral for end-stage renal disease: a region-wide survey in the south west of England. Nephrol Dial Transpl. 2002;17:1252–9.CrossRef
10.
go back to reference Dogan E, Erkoc R, Sayarlioglu H, Durmus A, Topal C. Effects of late referral to a nephrologist in patients with chronic renal failure. Nephrology. 2005;10:516–9.CrossRefPubMed Dogan E, Erkoc R, Sayarlioglu H, Durmus A, Topal C. Effects of late referral to a nephrologist in patients with chronic renal failure. Nephrology. 2005;10:516–9.CrossRefPubMed
11.
go back to reference Stack AG. Impact of timing of nephrology referral and pre-ESRD care on mortality risk among new ESRD patients in the United States. Am J Kidney Dis. 2003;41:310–8.CrossRefPubMed Stack AG. Impact of timing of nephrology referral and pre-ESRD care on mortality risk among new ESRD patients in the United States. Am J Kidney Dis. 2003;41:310–8.CrossRefPubMed
12.
go back to reference Lopez-Vargas PA, Craig JC, Gallagher MP, Walker RG, Snelling PL, Pedagogos E, et al. Barriers to timely arteriovenous fistula creation: a study of providers and patients. Am J Kidney Dis. 2011 (Epub ahead of print). Lopez-Vargas PA, Craig JC, Gallagher MP, Walker RG, Snelling PL, Pedagogos E, et al. Barriers to timely arteriovenous fistula creation: a study of providers and patients. Am J Kidney Dis. 2011 (Epub ahead of print).
13.
go back to reference Inaguma D, Tatematsu M, Shinjo H, Suzuki S, Mishima T, Inaba S, et al. Effect of an educational program on the predialysis period for patients with chronic renal failure. Clin Exp Nephrol. 2006;10:274–8.CrossRefPubMed Inaguma D, Tatematsu M, Shinjo H, Suzuki S, Mishima T, Inaba S, et al. Effect of an educational program on the predialysis period for patients with chronic renal failure. Clin Exp Nephrol. 2006;10:274–8.CrossRefPubMed
14.
go back to reference Lee T, Barker J, Allon M. Associations with predialysis vascular access management. Am J Kidney Dis. 2004;43:1008–13.CrossRefPubMed Lee T, Barker J, Allon M. Associations with predialysis vascular access management. Am J Kidney Dis. 2004;43:1008–13.CrossRefPubMed
15.
go back to reference Jungers P, Massy ZA, Nguyen-Khoa T, Choukroun G, Robino C, Fakhouri F, et al. Longer duration of predialysis nephrological care is associated with improved long-term survival of dialysis patients. Nephrol Dial Transpl. 2001;16:2357–64.CrossRef Jungers P, Massy ZA, Nguyen-Khoa T, Choukroun G, Robino C, Fakhouri F, et al. Longer duration of predialysis nephrological care is associated with improved long-term survival of dialysis patients. Nephrol Dial Transpl. 2001;16:2357–64.CrossRef
16.
go back to reference Lin CL, Wu MS, Hsu PY, Huang CC. Improvement of clinical outcome by early nephrology referral in type II diabetics on hemodialysis. Ren Fail. 2003;25:455–64.CrossRefPubMed Lin CL, Wu MS, Hsu PY, Huang CC. Improvement of clinical outcome by early nephrology referral in type II diabetics on hemodialysis. Ren Fail. 2003;25:455–64.CrossRefPubMed
17.
go back to reference Chan MR, Dall AT, Fletcher KE, Lu N, Trivedi H. Outcomes in patients with chronic kidney disease referred late to nephrologists: a meta-analysis. Am J Med. 2007;120:1063–70.CrossRefPubMed Chan MR, Dall AT, Fletcher KE, Lu N, Trivedi H. Outcomes in patients with chronic kidney disease referred late to nephrologists: a meta-analysis. Am J Med. 2007;120:1063–70.CrossRefPubMed
Metadata
Title
Nephrologist care for 12 months or more increases hemodialysis initiation with permanent vascular access
Authors
Daijo Inaguma
Ryoichi Ando
Masato Ikeda
Nobuhiko Joki
Fumihiko Koiwa
Yasuhiro Komatsu
Toshihumi Sakaguchi
Toshio Shinoda
Toshihiko Yamaka
Takashi Shigematsu
Publication date
01-10-2011
Publisher
Springer Japan
Published in
Clinical and Experimental Nephrology / Issue 5/2011
Print ISSN: 1342-1751
Electronic ISSN: 1437-7799
DOI
https://doi.org/10.1007/s10157-011-0472-7

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