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01-12-2010 | Review Article

Searching for novel intercellular signal-transducing molecules in the kidney and their clinical application

Authors: Kiyoshi Mori, Masashi Mukoyama, Kazuwa Nakao

Published in: Clinical and Experimental Nephrology | Issue 6/2010

Abstract

In this review, isolation and characterization of several kidney-derived molecules are described, namely carbonic anhydrase XIV, cysteine-rich protein 61, and kidney–liver-specific immunoglobulin-like protein. Features of neutrophil gelatinase-associated lipocalin (LCN2 or human neutrophil lipocalin) as a kidney differentiation inducer and renal injury biomarker and also as an iron-carrier protein are also summarized. Furthermore, the concepts of forest fire theory and the biology of siderophore-binding proteins are discussed.

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Title: Searching for novel intercellular signal-transducing molecules in the kidney and their clinical application
Authors: Kiyoshi Mori
Masashi Mukoyama
Kazuwa Nakao
Publication date: 01-12-2010
Publisher: Springer Japan
Published in: Clinical and Experimental Nephrology / Issue 6/2010
Print ISSN: 1342-1751
Electronic ISSN: 1437-7799
DOI: https://doi.org/10.1007/s10157-010-0320-1

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