Published in:
01-02-2012 | Note
Risk factors of septic shock in bacteremic acute pyelonephritis patients admitted to an ER
Authors:
Jae Hoon Lee, Yu Min Lee, Ji Hyun Cho
Published in:
Journal of Infection and Chemotherapy
|
Issue 1/2012
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Abstract
Our objective was to identify factors associated with septic shock in patients with bacteremic acute pyelonephritis who were admitted to our emergency department (ER). We performed a retrospective cohort study of 208 adult cases compiled between January 2000 and December 2010. The mean age of the 208 predominantly female (81.3%) adult cases enrolled during the study period was 65.9 ± 15.2 years. The overall mortality rate was 6.7% (14/208), but the mortality rate of 54 patients (26%, 54/208) who initially presented with shock was 25.9% (14/54). Multiple logistic regression analyses revealed that the independent risk factors for the occurrence of septic shock were the presence of a urinary tract obstruction (OR 4.391, 95% CI 1.782–10.821, P = 0.001), healthcare-associated infection (OR 3.491, 95% CI 1.585–7.692, P = 0.002), and liver cirrhosis (OR 4.609, 95% CI 1.395–15.222, P = 0.012). Therefore, physicians should be aware that appropriate early management is necessary to prevent fatal outcomes in patients with risk factors of septic shock.