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01-12-2020 | Photodynamic Therapy | The Last Image
Complete healing of perianal giant condyloma (buschke-löwenstein tumor) with imiquimod 5% cream alone
Published in: Techniques in Coloproctology | Issue 12/2020
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Local excision appears to be the mainstay of treatment to obtain adequate local control for perianal giant condylomas. Radical reconstructive surgery should be reserved for patients with malignant transformation, recurrence, or anal sphincter involvement. However, morbidity in patients undergoing extensive excision is high. Adjunct radiotherapy, photodynamic therapy, and imiquimod have been proposed in advanced or recurrent lesions. A 58-year-old human immunodeficiency virus–negative man was successfully treated for giant perianal condyloma using imiquimod 5% without surgery. Complete resolution of the condition was achieved after 2 months of topical treatment (Figs. 1, 2, 3, and 4).
Fig. 1
Appearance of the giant condyloma before treatment
Fig. 2
The neoformation after 20 days of topical therapy. Note the severe redness of the perianal skin caused by imiquimod
Fig. 3
After 40 days of applying the ointment: the neoformation appears considerably smaller
Fig. 4
Complete resolution after 2 months of topical treatment
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