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01-01-2018 | Case Report

Double pituitary adenomas associated with persistent trigeminal artery: a rare case report and the review of literature

Authors: Naohisa Miyagi, Ryou Doi, Terukazu Kuramoto, Kiyohiko Sakata, Shigeyuki Tahara, Yasuo Sugita, Motohiro Morioka

Published in: Neurosurgical Review | Issue 1/2018

Abstract

Multiple pituitary adenomas are rare. We present a quite unique case of double pituitary adenomas associated with persistent trigeminal artery (PTA) treated by endoscopic surgery. To the best of our knowledge, this is the first report in the literature. A 64-year-old woman was referred to our hospital for suspicion of acromegaly. Preoperative magnetic resonance imaging revealed two separate intrasellar masses with intrasellar vascular structure. Right cerebral angiography showed medial-type PTA. The patient underwent endoscopic transsphenoidal surgery and both tumors were resected completely. Postoperative immunohistopathologic examination revealed two histologic types of adenoma: the first tumor was positive for growth hormone (GH), while the second was considered nonfunctioning. Postoperatively, the patient’s serum levels of GH and insulin-like growth factor-1 returned to normal. We observed an extremely rare case of double pituitary adenomas associated with PTA. Preoperative neuroimaging and modern endoscopic surgery are valuable to confirm diagnosis of double pituitary adenomas and identify anatomical localization of PTA.

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Title: Double pituitary adenomas associated with persistent trigeminal artery: a rare case report and the review of literature
Authors: Naohisa Miyagi
Ryou Doi
Terukazu Kuramoto
Kiyohiko Sakata
Shigeyuki Tahara
Yasuo Sugita
Motohiro Morioka
Publication date: 01-01-2018
Publisher: Springer Berlin Heidelberg
Published in: Neurosurgical Review / Issue 1/2018
Print ISSN: 0344-5607
Electronic ISSN: 1437-2320
DOI: https://doi.org/10.1007/s10143-017-0924-y

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Double pituitary adenomas associated with persistent trigeminal artery: a rare case report and the review of literature

Abstract

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Springer Medicine

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