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Emergency Radiology
Published in: Emergency Radiology 3/2020

01-06-2020 | Computed Tomography | Review Article

Beyond pyogenic liver abscess: a comprehensive review of liver infections in emergency settings

Authors: Pankaj Nepal, Vijayanadh Ojili, Shruti Kumar, Neeraj Kaur, Arpit Nagar

Published in: Emergency Radiology | Issue 3/2020

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Abstract

Hepatobiliary infections are commonly encountered in emergency settings ranging from common pathology such as pyogenic abscess to relatively uncommon and rare etiologies. Since extensive literature is already available on imaging of more common bacterial infections, for the sake of focused discussion, this review will discuss radiological appearance of less commonly encountered hepatic infections of fungal, parasitic, viral, and tubercular etiologies. Epidemiological and clinical information remain extremely important for obtaining more accurate presumptive diagnosis. In the era of diverse population migration, a modern-era radiologist must be well versed about the imaging spectrum of liver infections.
Literature
1.
Mortele KJ, Segatto E, Ros PR (2004) The infected liver: radiologic-pathologic correlation. Radio Graphics 24:937–955
2.
3.
Bächler P, Baladron MJ, Menias C, Beddings I, Loch R, Zalaquett E, Vargas M, Connolly S, Bhalla S, Huete Á (2016) Multimodality imaging of liver infections: differential diagnosis and potential pitfalls. RadioGraphics 36:1001–1023PubMedCrossRef
4.
Doyle DJ, Hanbidge AE, O’Malley ME (2006) Imaging of hepatic infections. Clin Radiol 61:737–748PubMedCrossRef
5.
Radin D, Ralls P, Colletti P, Halls J (1988) CT of amebic liver abscess. Am J Roentgenol 150:1297–1301CrossRef
6.
Hughes MA, Petri WA Jr (2000) Amebic liver abscess. Infect Dis Clin N Am 14:565–582CrossRef
7.
Benedetti NJ, Desser TS, Jeffrey RB (2008) Imaging of hepatic infections. Ultrasound Q 24:267–278PubMedCrossRef
8.
Ralls PW, Colletti PM, Quinn MF et al (1982) Sonographic findings in hepatic amebic abscess. Radiology 145:123–126PubMedCrossRef
9.
Jeffrey RB Jr, Tolentino CS, Chang FC et al (1988) CT of small pyogenic hepatic abscesses: the cluster sign. AJR Am J Roentgenol 151:487–489PubMedCrossRef
10.
Elizondo G, Weissleder R, Stark DD, Todd LE, Compton C, Wittenberg J, Ferrucci JT Jr (1987) Amebic liver abscess: diagnosis and treatment evaluation with MR imaging. Radiology 165:795–800PubMedCrossRef
11.
Rofsky NM, Fleishaker H (1995) CT and MRI of diffuse liver disease. Semin Ultrasound CT MR 16:16–33PubMedCrossRef
12.
13.
Gore RM, Miller FH, Yaghmai V (1998) Acquired immunodeficiency syndrome (AIDS) of the abdominal organs: imaging features. Semin Ultrasound CT MR 19:175–189PubMedCrossRef
14.
Keaveny AP, Karasik MS (1998) Hepatobiliary and pancreatic infections in AIDS: part one. AIDS Patient Care STDs 12:347–357PubMedCrossRef
15.
Reeders JW, Yee J, Gore RM et al (2004) Gastrointestinal infection in the immunocompromised (AIDS) patient. Eur Radiol 14:E84–E102PubMed
16.
Bonacini M (1992) Hepatobiliary complications in patients with human immunodeficiency virus infection. Am J Med 92:404–411PubMedCrossRef
17.
Schacker T, Collier AC, Hughes J et al (1997) Clinical and epidemiologic features of primary HIV infection. Arch Intern Med 125:257–264
18.
Pedrosa I, Saíz A, Arrazola J, Ferreirós J, Pedrosa CS (2000) Hydatid disease: radiologic and pathologic features and complications. RadioGraphics 20:795–817PubMedCrossRef
19.
Eckert J, Gemmell MA, Meslin FX, Pawłowski ZS. WHO/OIE manual on echinococcosis in humans and animals: a public health problem of global concern. World Organisation for Animal Health (Office International des Epizooties) and World Health Organization. Paris: WHO; 2001
20.
Working Group WI (2003) International classification of ultrasound images in cystic echinococcosis for application in clinical and field epidemiological settings. Acta Trop 85:253–261CrossRef
21.
22.
Esfahani F, Roohlamini SA, Vessal K (1988) Ultrasonography of hepatic hydatid cysts: new diagnostic signs. J Ultrasound Med 7:443–450PubMedCrossRef
23.
24.
Marani SA, Canossi GC, Nicoli FA, Alberti GP, Monni SG, Casolo PM (1990) Hydatid disease: MR imaging study. Radiology 175:701–706PubMedCrossRef
25.
26.
Didier D, Weiler S, Rohmer P, Lassegue A, Deschamps JP, Vuitton D, Miguet JP, Weill F (1985) Hepatic alveolar echinococcosis: correlative US and CT study. Radiology 154:179–186PubMedCrossRef
27.
28.
29.
Passos MCF, Silva LC, Ferrari TCA, Faria LC (2009) Ultrasound and CT findings in hepatic and pancreatic parenchyma in acute schistosomiasis. Br J Radiol 82:e145–e147PubMedCrossRef
30.
Cesmeli E, Vogelaers D, Voet D, Duyck P, Peleman R, Kunnen M, Afschrift M (1997) Ultrasound and CT changes of liver parenchyma in acute schistosomiasis. Br J Radiol 70:758–760PubMedCrossRef
31.
Nepal P, Ojili V, Songmen S, Batchala P, Kumar D, Nagar AM (2019) Multisystem imaging review of human schistosomiasis: characteristic imaging findings. Clin Imaging 54:163–171PubMedCrossRef
32.
Kabaalioglu A, Ceken K, Alimoglu E, Saba R, Cubuk M, Arslan G, Apaydin A (2007) Hepatobiliary fascioliasis: sonographic and CT findings in 87 patients during the initial phase and long-term follow-up. AJR Am J Roentgenol 189:824–828PubMedCrossRef
33.
Cevikol C, Karaali K, Senol U, Kabaalioğlu A, Apaydin A, Saba R, Lüleci E (2003) Human fascioliasis: MR imaging findings of hepatic lesions. Eur Radiol 13:141–148PubMedCrossRef
34.
Hashmi MA, De JK (2009) Biliary ascariasis on magnetic resonance cholangiopancreatography. J Global Infect Dis 1:144–145CrossRef
35.
Sundriyal D, Bansal S, Kumar N, Sharma N (2015) Biliary ascariasis: radiological clue to diagnosis. Oxf Med Case Reports 26:246–247CrossRef
36.
37.
Heffernan EJ, Geoghegan T, Munk PL, Ho SG, Harris AC (2009) Recurrent pyogenic cholangitis: from imaging to intervention. Am J Roentgenol 192:W28–W35CrossRef
38.
Lim J, Ko Y, Lee D, Kim S (1989) Clonorchiasis: sonographic findings in 59 proved cases. Am J Roentgenol 152:761–764CrossRef
39.
Hagspiel KD, Kempf W, Hailemariam S, Marincek B (1995) Mucormycosis of the liver: CT findings. Am J Roentgenol 165:340–342CrossRef
40.
Petrikkos G, Skiada A, Lortholary O et al (2013) Epidemiology and clinical manifestations of mucormycosis. Clin Infect Dis 2012:S23–S34
41.
Parfrey NA. Improved diagnosis and prognosis of mucormycosis: a clinicopathologic study of 33 cases, Medicine (Baltimore), 1986, vol. 65 (pg. 113–123)
42.
Lamps LW, Molina CP, West AB, Haggitt RC, Scott MA (2000) The pathologic spectrum of gastrointestinal and hepatic histoplasmosis. Am J Clin Pathol 113:64–72PubMedCrossRef
43.
Radin DR (1991) Disseminated histoplasmosis: abdominal CT findings in 16 patients. AJR Am J Roentgenol 157:955–958PubMedCrossRef
44.
Burrill J, Williams CJ, Bain G, Conder G, Hine AL, Misra RR (2007) Tuberculosis: a radiologic review. Radiographics 27:1255–1273PubMedCrossRef
45.
Jadvar R, Mindelzun RE, Olcott EW, Levitt DB (1997) Still the great mimicker: abdominal tuberculosis. AJR Am J Roentgenol 168:1455–1460PubMedCrossRef
46.
47.
Jain R, Sawhney S, Gupta RG, Acharya SK (1999) Sonographic appearances and percutaneous management of primary tuberculous liver abscess. J Clin Ultrasound 27:159–163PubMedCrossRef
48.
49.
Kawamori Y, Matsui O, Kitagawa K, Kadoya M, Takashima T, Yamahana T (1992) Macronodular tuberculoma of the liver: CT and MR findings. AJR Am J Roentgenol 158:311–313PubMedCrossRef
50.
Nyberg DA, Federle MP, Jeffrey RB, Bottles K, Wofsy CB (1985) Abdominal CT findings of disseminated Mycobacterium avium-intracellulare in AIDS. AJR Am J Roentgenol 145:297–299PubMedCrossRef
51.
Radin DR (1991) Intraabdominal Mycobacterium tuberculosis vs Mycobacterium avium-intracellulare infections in patients with AIDS: distinction based on CT findings. AJR 156:487–491PubMedCrossRef
52.
53.
Jones EA, Manaster BJ, May DA et al (2000) Neuropathic osteoarthropathy: diagnostic dilemmas and differential diagnosis. Radiographics 20:S279–S293PubMedCrossRef
54.
Mendiratta V, Malik M, Gurtoo A, Chander R (2014) Fulminant hepatic failure in a 15 year old boy with borderline lepromatous leprosy and type 2 reaction. Lepr Rev 85:54–57PubMed
55.
Ferrari TCA, Arau’jo MG, Ribeiro MMF (2002) Hepatic involvement in lepromatous leprosy. Lepr Rev 73:72–75PubMed
56.
Choi EK, Lamps LW (2018) Granulomas in the liver, with a focus on infectious causes. Surg Pathol Clin 11:231–250PubMedCrossRef
Metadata
Title
Beyond pyogenic liver abscess: a comprehensive review of liver infections in emergency settings
Authors
Pankaj Nepal
Vijayanadh Ojili
Shruti Kumar
Neeraj Kaur
Arpit Nagar
Publication date
01-06-2020
Publisher
Springer International Publishing
Published in
Emergency Radiology / Issue 3/2020
Print ISSN: 1070-3004
Electronic ISSN: 1438-1435
DOI
https://doi.org/10.1007/s10140-020-01757-6

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