Top

Published in:

01-04-2022 | Glaucoma | Original Article

Selective laser trabeculoplasty lowered the untreated fellow eye long-term intraocular pressure: a 3-year observational study

Authors: Yan Liu, Xiang Fan, Lingling Wu

Published in: Lasers in Medical Science | Issue 3/2022

Abstract

To explore the long-term intraocular pressure (IOP)-lowering effect of monocular selective laser trabeculoplasty (SLT) in the untreated fellow eyes of open-angle glaucoma (OAG) patients. This was a retrospective observational study. Consecutive Chinese OAG patients who received monocular SLT treatment were included in this study. One hundred and eighty degree SLT was conducted as adjunctive treatment when anti-glaucoma medication was not sufficiently effective after clinical evaluation. Treatment success was defined as more than 20% IOP reduction of the baseline IOP levels. IOP-decreasing amplitude and SLT success rate of both eyes were investigated during the 3-year follow-up period. Age, gender, baseline IOP levels, number of medications, and SLT energy parameters were analyzed to determine its influence on IOP reduction effect and treatment success rate. A total of 32 Chinese OAG patients were included in this study and 25 of them completed the 3-year follow-ups. Their pretreatment IOPs were 18.85 ± 2.81 mmHg in the treated eyes and 17.38 ± 2.37 mmHg in the fellow eyes. At the 3-year follow-up visits, IOP decreased to 2.76 ± 3.72 mmHg (14.16%) in the treated eyes and 2.16 ± 2.73 mmHg (11.95%) in the fellow eyes, with a success rate of 47.83% (11 in 23 cases) and 44.00% (11 in 25 cases), respectively. IOPs of both eyes decreased significantly after SLT from 6 months and lasted to 3 years after treatment. Baseline IOP level was positively correlated with IOP reduction in the treated eyes and other factors were not correlated with IOP reduction and treatment success. Monocular SLT treatment as adjunctive treatment could lower IOPs not only in the treated eyes but also in the untreated eyes in poor medication-controlled OAG patients. In addition, its IOP reduction effect could last to 3 years after treatment in clinical practice.

Available only for authorised users

Zhou Y, Aref AA (2017) A review of selective laser trabeculoplasty: recent findings and current perspectives[J]. Ophthalmol Therapy 6(1):19–32CrossRef

Mcilraith I, Strasfeld M, Coley G et al (2006) Selective laser trabeculoplasty as initial and adjunctive treatment for open-angle glaucoma[J]. Am J Ophthalmol 142(2):1CrossRef

Latina MA, Tumbocon JAJ (2002) Selective laser trabeculoplasty: a new treatment option for open angle glaucoma[J]. Curr Opin Ophthalmol 13(2):94–96CrossRef

Vincenzo R, Antonio B, Annesa C et al (2009) Selective laser trabeculoplasty versus argon laser trabeculoplasty in patients with uncontrolled open-angle glaucoma[J]. Eur J Ophthalmol 19(3):429–434CrossRef

Mallah MKE, Walsh MM, Stinnett SS et al (2010) Selective laser trabeculoplasty reduces mean IOP and IOP variation in normal tension glaucoma patients[J]. Clin Ophthalmol 4(1):889–893PubMedPubMedCentral

Ali Aljasim L, Owaidhah O, Edward DP (2016) Selective laser trabeculoplasty in primary angle-closure glaucoma after laser peripheral iridotomy: a case-control study. J Glaucoma 25(3):e253–8. https://doi.org/10.1097/IJG.0000000000000282

Singh IM (2015) Long-term effect of selective laser trabeculoplasty on intraocular pressure in pseudoexfoliation glaucoma[J]. Klin Monatsbl Augenheilkd 232(04):405–408CrossRef

Maleki A, Swan RT, Lasave AF, Ma L, Foster CS (2016) Selective laser trabeculoplasty in controlled uveitis with steroid-induced glaucoma. Ophthalmology 123(12):2630–2632. https://doi.org/10.1016/j.ophtha.2016.07.027

Latina MA, Sibayan SA, Dong HS et al (1998) Q-switched 532-nm Nd:YAG laser trabeculoplasty (selective laser trabeculoplasty): a multicenter, pilot, clinical study 1[J]. Ophthalmology 105(11):2089–2090CrossRef

10.

Rhodes KM, Weinstein R, Saltzmann RM et al (2009) Intraocular pressure reduction in the untreated fellow eye after selective laser trabeculoplasty[J]. Curr Med Res Opin 25(3):787–796CrossRef

11.

Onakoya AO, Olowoyeye AO, Onyekwelu OM, Abikoye TM (2015) Intraocular pressure changes post selective laser trabeculoplasty in the contralateral untreated eyes of Nigerian patients with primary open angle glaucoma. Nig Q J Hosp Med 25(2):133–138

12.

Vikas G, Shan F, Gardner BJ et al (2017) Mechanism of action of selective laser trabeculoplasty and predictors of response[J]. Investigative Opthalmology & Visual Science 58(3):1462–1468CrossRef

13.

Foster PJ, Buhrmann R, Quigley HA et al (2002) The definition and classification of glaucoma in prevalence surveys. Br J Ophthalmol 86:238–242CrossRef

14.

Juzych MS, Chopra V, Banitt MR, Hughes BA, Kim C, Goulas MT, Shin DH (2004) Comparison of long-term outcomes of selective laser trabeculoplasty versus argon laser trabeculoplasty in open-angle glaucoma. Ophthalmology 111(10):1853–1859. https://doi.org/10.1016/j.ophtha.2004.04.030

15.

Weinand FS, Althen F (2006) Long-term clinical results of selective laser trabeculoplasty in the treatment of primary open angle glaucoma[J]. Eur J Ophthalmol 16(1):100CrossRef

16.

Ayala M (2014) Long-term outcomes of selective laser trabeculoplasty (SLT) treatment in pigmentary glaucoma patients[J]. J Glaucoma 23(9):32–34CrossRef

17.

Kramer T (2001) Comparison of the morphologic changes after selective laser trabeculoplasty and argon laser trabeculoplasty in human eye bank eyes[J]. Ophthalmology 108(4):773–779CrossRef

18.

Kagan DB, Gorfinkel NS, Hutnik CM (2013) Mechanisms of selective laser trabeculoplasty: a review[J]. Clin Exp Ophthalmol 42(7):675CrossRef

19.

Alvarado JA, Yeh RF, Franse-Carman L, Marcellino G, Brownstein MJ (2005) Interactions between endothelia of the trabecular meshwork and of Schlemm's canal: a new insight into the regulation of aqueous outflow in the eye. Trans Am Ophthalmol Soc 103:148–162PubMedPubMedCentral

20.

Turani Z, Fatemizadeh E, Blumetti T, Daveluy S, Moraes AF, Chen W, Mehregan D, Andersen PE, Nasiriavanaki M (2019) Optical radiomic signatures derived from optical coherence tomography images improve identification of melanoma. Cancer Res 79(8):2021–2030. https://doi.org/10.1158/0008-5472

21.

Pillunat KR, Spoerl E, Elfes G, Pillunat LE (2016) Preoperative intraocular pressure as a predictor of selective laser trabeculoplasty efficacy. Acta Ophthalmol 94(7):692–696. https://doi.org/10.1111/aos.13094CrossRefPubMed

22.

Chun M, Gracitelli CP, Lopes FS, Biteli LG, Ushida M, Prata TS (2016) Selective laser trabeculoplasty for early glaucoma: analysis of success predictors and adjusted laser outcomes based on the untreated fellow eye. BMC Ophthalmol 16(1):206. https://doi.org/10.1186/s12886-016-0385-zCrossRefPubMedPubMedCentral

23.

Lee JW, Lai JS (2016) A review of selective laser trabeculoplasty in the Hong Kong Chinese population. Hong Kong Med J 22(2):165–170PubMed

24.

Lai JS, Chua JK, Tham CC, Lam DS (2004 Aug) Five-year follow up of selective laser trabeculoplasty in Chinese eyes. Clin Exp Ophthalmol 32(4):368–372. https://doi.org/10.1111/j.1442-9071.2004.00839.xCrossRefPubMed

25.

Lee JW, Liu CC, Chan JC, Lai JS (2014 Jun-Jul) Predictors of success in selective laser trabeculoplasty for Chinese open-angle glaucoma. J Glaucoma 23(5):321–325. https://doi.org/10.1097/IJG.0000000000000049CrossRefPubMed

26.

Lee JW, Liu CC, Chan JCh, Wong RL, Wong IY, Lai JS (2014) Predictors of success in selective laser trabeculoplasty for primary open angle glaucoma in Chinese. Clin Ophthalmol 8:1787–1791. https://doi.org/10.2147/OPTH.S69166

27.

Lee JW, Wong MO, Liu CC, Lai JS (2015) Optimal selective laser trabeculoplasty energy for maximal intraocular pressure reduction in open-angle glaucoma. J Glaucoma 24(5):e128–31. https://doi.org/10.1097/IJG.0000000000000215

28.

Lee W, Liu C, Chan J et al (2014) Predictors of success in selective laser trabeculoplasty for Chinese open-angle glaucoma[J]. J Glaucoma 23(28):321–325CrossRef

Title: Selective laser trabeculoplasty lowered the untreated fellow eye long-term intraocular pressure: a 3-year observational study
Authors: Yan Liu
Xiang Fan
Lingling Wu
Publication date: 01-04-2022
Publisher: Springer London
Keywords: Glaucoma
Laser
Published in: Lasers in Medical Science / Issue 3/2022
Print ISSN: 0268-8921
Electronic ISSN: 1435-604X
DOI: https://doi.org/10.1007/s10103-021-03253-w

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Selective laser trabeculoplasty lowered the untreated fellow eye long-term intraocular pressure: a 3-year observational study

Abstract

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Please log in to get access to this content

Other articles of this Issue 3/2022

The facilitating effect of blue light on the antifungal agent susceptibilities of passaged conidia from the ocular-derived Fusarium solani species complex

Correction to: Q‑S laser micro‑drilling and multipass full‑beam Q‑S laser for tattoo removal — a case series

Effects of photobiomodulation therapy in chondrocyte response by in vitro experiments and experimental model of osteoarthritis in the knee of rats

Effects of multiple modes of UltraPulse fractional CO2 laser treatment on extensive scarring: a retrospective study

Effects of low-level laser therapy on reducing pain, edema, and trismus after orthognathic surgery: a systematic review

Low-energy laser therapy application on knee joints as an auxiliary treatment in patients with polyarticular juvenile idiopathic arthritis: a dual-arm randomized clinical trial