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Published in: Lasers in Medical Science 3/2019

01-04-2019 | Original Article

Blue laser imaging with acetic acid enhancement improved the detection rate of gastric intestinal metaplasia

Authors: Honglei Chen, Xiaobin Wu, Yanan Liu, Qiuning Wu, Yi Lu, Chujun Li

Published in: Lasers in Medical Science | Issue 3/2019

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Abstract

Our aim was to evaluate the ability of blue laser imaging (BLI) combined with acetic acid (BLI-AA) to detect gastric intestinal metaplasia (GIM). Participants undergoing gastroscopy from July 2017 to February 2018 in our hospital were enrolled prospectively. The abilities of white light imaging endoscopy, BLI endoscopy, and BLI-AA to detect GIM were compared. One hundred six patients undergoing gastroscopy met the inclusion criteria. GIM was diagnosed in 41 patients. For BLI-AA, the sensitivity, specificity, positive predictive, and negative predictive values were 85.4%, 84.6%, 77.8%, and 90.2% respectively. The diagnostic accuracy rate for BLI-AA was 84.9%, which was higher than that of white light imaging endoscopy and BLI endoscopy. For target biopsy, the GIM detection rate for the BLI-AA mode was significantly higher (77.8%, 105/135) than that for the BLI mode (58.3%, 84/144) or the white light endoscopy mode (40.4%, 57/141) (p < 0.05). BLI-AA is an efficient and simple method for the detection of GIM.
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Metadata
Title
Blue laser imaging with acetic acid enhancement improved the detection rate of gastric intestinal metaplasia
Authors
Honglei Chen
Xiaobin Wu
Yanan Liu
Qiuning Wu
Yi Lu
Chujun Li
Publication date
01-04-2019
Publisher
Springer London
Published in
Lasers in Medical Science / Issue 3/2019
Print ISSN: 0268-8921
Electronic ISSN: 1435-604X
DOI
https://doi.org/10.1007/s10103-018-2629-z

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