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01-07-2011 | Original Article

Experience with non-ablative fractional photothermolysis with a dual-mode laser device (1,440/1,320 nm): no considerable clinical effect on hypertrophic/acne scars and facial wrinkles

Authors: Philipp Babilas, Stephan Schreml, Tatiana Eames, Ulrich Hohenleutner, Michael Landthaler, Silvia Hohenleutner

Published in: Lasers in Medical Science | Issue 4/2011

Abstract

In the literature, non-ablative fractionated photothermolysis (nFP) is accredited with improvement of wrinkles and scars combined with a reduced downtime. The purpose of this work was to evaluate the impact of a combination laser (1,320/1,440 nm) for nFP on hypertrophic scars, acne scars, and facial wrinkles. Thirty-six patients suffering from hypertrophic scars (n = 7), acne scars (n = 9), and wrinkles (n = 20) were treated using a combination Nd:YAG laser [λ_em = 1,320 and 1,440 nm, pulse duration: 3-ms single pulse, fluence: 8.0–9.0 J/cm² (1,320 nm); 2.0–2.5 J/cm² (1,440 nm)]. The appearance of the treated condition was evaluated in a retrospective study by two blinded investigators based on follow-up photographs and by patient self-assessment. The frequency of side-effects was also assessed. Both patients and blinded observers rated the treatment results for hypertrophic scars and acne scars as slight improvement, and for wrinkles as equal as compared to baseline. No serious side-effects were reported. The light device used did not lead to a considerable clinical improvement of hypertrophic scars, acne scars, or wrinkles in this study.

Tan MH, Dover JS, Hsu TS, Arndt KA, Stewart B (2004) Clinical evaluation of enhanced nonablative skin rejuvenation using a combination of a 532 and a 1,064 nm laser. Lasers Surg Med 34(5):439–445PubMedCrossRef

Zelickson BD, Kilmer SL, Bernstein E, Chotzen VA, Dock J, Mehregan D, Coles C (1999) Pulsed dye laser therapy for sun damaged skin. Lasers Surg Med 25(3):229–236PubMedCrossRef

Goldberg DJ (2000) Full-face nonablative dermal remodeling with a 1320 nm Nd:YAG laser. Dermatol Surg 26(10):915–918PubMedCrossRef

Lupton JR, Williams CM, Alster TS (2002) Nonablative laser skin resurfacing using a 1540 nm erbium glass laser: a clinical and histologic analysis. Dermatol Surg 28(9):833–835PubMedCrossRef

Manstein D, Herron GS, Sink RK, Tanner H, Anderson RR (2004) Fractional photothermolysis: a new concept for cutaneous remodeling using microscopic patterns of thermal injury. Lasers Surg Med 34(5):426–438PubMedCrossRef

Dang Y, Ren Q, Liu H, Ma J, Zhang J (2006) Effects of the 1,320-nm Nd:YAG laser on transepidermal water loss, histological changes, and collagen remodeling in skin. Lasers Med Sci 21(3):147–152PubMedCrossRef

Khan MH, Sink RK, Manstein D, Eimerl D, Anderson RR (2005) Intradermally focused infrared laser pulses: thermal effects at defined tissue depths. Lasers Surg Med 36(4):270–280PubMedCrossRef

Bene NI, Weiss MA (2006) Munavalli G, Weiss RA. Comparison of histological features of 1550 nm fractional resurfacing and microlens array scattering of 1440 nm. Lasers Surg Med 38(Suppl 18):26

Weiss RA, Gold M, Bene N, Biron JA, Munavalli G, Weiss M, Beasley K (2006) Prospective clinical evaluation of 1440-nm laser delivered by microarray for treatment of photoaging and scars. J Drugs Dermatol 5(8):740–744PubMed

10.

Alexiades-Armenakas M (2007) Nonablative skin tightening with a variable depth heating 1310-nm wavelength laser in combination with surface cooling. J Drugs Dermatol 6(11):1096–1103PubMed

11.

Alexiades-Armenakas MR, Dover JS, Arndt KA (2008) The spectrum of laser skin resurfacing: nonablative, fractional, and ablative laser resurfacing. J Am Acad Dermatol 58(5):719–737, quiz 738–740PubMedCrossRef

12.

Dang Y, Ren Q, Hoecker S, Liu H, Ma J, Zhang J (2005) Biophysical, histological and biochemical changes after non-ablative treatments with the 595 and 1320 nm lasers: a comparative study. Photodermatol Photoimmunol Photomed 21(4):204–209PubMedCrossRef

13.

DeHoratius DM, Dover JS (2007) Nonablative tissue remodeling and photorejuvenation. Clin Dermatol 25(5):474–479PubMedCrossRef

14.

Fulchiero GJ Jr, Parham-Vetter PC, Obagi S (2004) Subcision and 1320-nm Nd:YAG nonablative laser resurfacing for the treatment of acne scars: a simultaneous split-face single patient trial. Dermatol Surg 30(10):1356–1359, discussion 1360PubMedCrossRef

15.

Goldberg DJ (2002) Nonablative dermal remodeling: does it really work? Arch Dermatol 138(10):1366–1368PubMedCrossRef

16.

Haedersdal M, Moreau KE, Beyer DM, Nymann P, Alsbjorn B (2009) Fractional nonablative 1540 nm laser resurfacing for thermal burn scars: a randomized controlled trial. Lasers Surg Med 41(3):189–195PubMedCrossRef

17.

Hohenleutner S, Hohenleutner U, Landthaler M (2002) Nonablative wrinkle reduction: treatment results with a 585-nm laser. Arch Dermatol 138(10):1380–1381PubMedCrossRef

18.

Hohenleutner S, Koellner K, Lorenz S, Landthaler M, Hohenleutner U (2005) Results of nonablative wrinkle reduction with a 1,450-nm diode laser: difficulties in the assessment of "subtle changes". Lasers Surg Med 37(1):14–18PubMedCrossRef

19.

Leffell DJ (2002) Clinical efficacy of devices for nonablative photorejuvenation. Arch Dermatol 138(11):1503–1508PubMedCrossRef

20.

Manstein D, Zurakowski D, Thongsima S, Laubach H, Chan HH (2009) The effects of multiple passes on the epidermal thermal damage pattern in nonablative fractional resurfacing. Lasers Surg Med 41(2):149–153PubMedCrossRef

21.

Walgrave SE, Ortiz AE, MacFalls HT, Elkeeb L, Truitt AK, Tournas JA, Zelickson BD, Zachary CB (2009) Evaluation of a novel fractional resurfacing device for treatment of acne scarring. Lasers Surg Med 41(2):122–127PubMedCrossRef

22.

Woo WK, Handley JM (2003) A pilot study on the treatment of facial rhytids using nonablative 585-nm pulsed dye and 532-nm Nd:YAG lasers. Dermatol Surg 29(12):1192–1195, discussion 1195PubMedCrossRef

23.

Landthaler M, Ulrich H, Hohenleutner S, Wimmershoff M, Hohenleutner U (2004) Role of laser therapy in dermatology—clinical aspects. Dermatology 208(2):129–134PubMedCrossRef

24.

Lloyd JR (2008) Effect of fluence on efficacy using the 1440 nm laser with CAP technology for the treatment of rhytids. Lasers Surg Med 40(6):387–389PubMedCrossRef

25.

Niwa AB, Mello AP, Torezan LA, Osorio N (2009) Fractional photothermolysis for the treatment of hypertrophic scars: clinical experience of eight cases. Dermatol Surg 35(5):773–777, discussion 777–778PubMedCrossRef

Title: Experience with non-ablative fractional photothermolysis with a dual-mode laser device (1,440/1,320 nm): no considerable clinical effect on hypertrophic/acne scars and facial wrinkles
Authors: Philipp Babilas
Stephan Schreml
Tatiana Eames
Ulrich Hohenleutner
Michael Landthaler
Silvia Hohenleutner
Publication date: 01-07-2011
Publisher: Springer-Verlag
Published in: Lasers in Medical Science / Issue 4/2011
Print ISSN: 0268-8921
Electronic ISSN: 1435-604X
DOI: https://doi.org/10.1007/s10103-011-0893-2

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Experience with non-ablative fractional photothermolysis with a dual-mode laser device (1,440/1,320 nm): no considerable clinical effect on hypertrophic/acne scars and facial wrinkles

Abstract

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