Top

Published in:

01-07-2011 | Original Article

Study of short-pulse laser propagation in biological tissue by means of the boundary element method

Authors: Mohammad Ali Ansari, Reza Massudi

Published in: Lasers in Medical Science | Issue 4/2011

Abstract

Propagation of short pulses of light through biological tissues can be studied by numerically solving the diffusion equation. The boundary integral method was used to convert the differential equation to integral form and the result was solved using the boundary element method. The effects of different optical parameters of the tissue, i.e. scattering, absorption coefficients and anisotropic factor, on temporal evolution of the diffusely reflected pulse were studied. The results were compared with those obtained using the finite difference time domain method and the boundary integral method was found to be more precise and faster than the last method. The method can be used to investigate reflected pulses in the study of cell morphology and tumours in different types of tissue.

Kuz’min VL, Romanov VP, Kozhevnikov SV, Meglinskii IV (2006) Simulation of the propagation of a light pulse in a randomly inhomogeneous medium. Opt Spectrosc 100:767–775CrossRef

Liu F, Yoo KM, Alfano RR (1993) Ultrafast laser-pulse transmission and imaging through biological tissues. Appl Opt 32:554–558PubMedCrossRef

Sakami M, Mitra K, Vo-Dinh T (2002) Analysis of short- pulse laser photon transport through tissues for optical tomography. Opt Lett 27:336–338PubMedCrossRef

Braun M, Gilch P, Zinth W (2007) Ultrashort laser pulses in biology and medicine. Springer, New York

Alerstam E, Andersson-Engels S, Svensson T (2008) Improved accuracy in time-domain diffuse reflectance spectroscopy. Opt Express 16:10440–10454PubMedCrossRef

Martelli F, Sassarolli A, Del Bianco S, Zaccanti G (2007) Solution of time-dependent diffuse equation for a three-layer medium: application to study photon migration through a simplified adult head model. Phys Med Biol 52:2827–2843PubMedCrossRef

Guo Z, Kumar S (2000) Equitant isotropic scattering formulation for transient short-pulse radiative transfer in anisotropic scattering planar media. Appl Opt 39:4411–4417PubMedCrossRef

Pal G, Basu S, Mitra K, Vo-Dinh T (2006) Time-resolved optical tomography using short pulse laser for tumour detection. Appl Opt 45:6270–6282PubMed

Chai JC (2003) Transient photon transport in turbid media with an irregularly shaped foreign object. Opt Rev 10:609–610CrossRef

10.

Das C, Trivedi A, Mitra K, Vo-Dinh T (2003) Short pulse laser propagation through tissues for biomedical imaging. J Phys D Appl Phys 38:1714–1721CrossRef

11.

Mitra K, Kumar S (1999) Development and comparison of models for light pulse transport through scattering absorbing media. Appl Opt 38:188–196PubMedCrossRef

12.

Hall DJ, Hebden JC, Deply DT (1997) Imaging very-low-contrast objects in breast like scattering media with a time resolved method. Appl Opt 36:7270–7276PubMedCrossRef

13.

Yoo KM, Alfano RR (1990) Time resolved coherent and incoherent component of forward light scattering in random media. Opt Lett 15:320–322PubMedCrossRef

14.

Trivedi A, Basu S, Mitra K (2005) Temporal analysis of reflected optical signal for short pulse laser interaction with non-homogeneous tissue phantom. J Quant Spectrosc Radiat Transfer 93:337–348CrossRef

15.

Hopen CY (1999) Optical pulse propagation through a slab of random medium. Waves Random Media 9:551–560CrossRef

16.

Boas D, Culver J, Stott J, Dunn A (2002) Three dimensional Monte Carlo code for photon migration through complex heterogeneous media including the adult human head. Opt Express 10:159–170PubMed

17.

Berrocal E, Meglinski I, Jermy M (2005) New model for light propagation in highly inhomogeneous polydisperse turbid media with applications in spray diagnostics. Opt Express 13:9181–9195PubMedCrossRef

18.

Berrocal E, Sedarsky DL, Paciaroni ME, Meglinski IV, Linne MA (2009) Laser light scattering in turbid media Part II: Spatial and temporal analysis of individual scattering orders via Monte Carlo simulation. Opt Express 17:13792–13809PubMedCrossRef

19.

Handapangoda CC, Premaratne M, Yeo L, Friend J (2008) Laguerre Runge-Kutta-Fehlberg method for simulating laser pulse propagation in biological tissue. IEEE J Sel Top Quantum Electron 14:105–112CrossRef

20.

Wang LV, Wu HI (2007) Biomedical optics: principles and imaging. Wiley-Interscience, New Jersey

21.

Hasegawa Y, Yamada Y, Tamura M, Nomura Y (1991) Monte Carlo simulation of light transmission through living tissues. Appl Opt 30:4515–4520PubMedCrossRef

22.

Guo Z, Kumar S, San KC (2000) Multidimensional Monte Carlo simulation of short-pulse laser transport in scattering media. J Thermophys Heat Transfer 14:504–511CrossRef

23.

Hielscher AH, Alcouffe RE, Barbour RL (1998) Comparison of finite-difference transport and diffusion calculations for photon migration in homogeneous and heterogeneous tissues. Phys Med Biol 43:1285–1302PubMedCrossRef

24.

Guo Z, Aber J, Garetz BA, Kumar S (2002) Monte Carlo simulation and experiments of pulsed radiative transfer. J Quant Spectrosc Radiat Transfer 73:159–168CrossRef

25.

Guo Z, Kumar S (2001) Discrete-ordinates solution of short-pulsed laser transport in two-dimensional turbid media. Appl Opt 40:3156–3163PubMedCrossRef

26.

Tanifuji T, Hijikata M (2002) Finite difference time domain (FDTD) analysis of optical pulse responses in biological tissues for spectroscopic diffused optical tomography. IEEE Trans Med Imaging 21:181–184PubMedCrossRef

27.

Ichitsubo K, Tanifuji T (2005) Time-resolved noninvasive optical parameters determination in three-dimensional biological tissue using finite difference time domain analysis with nonuniform grids for diffusion equations, Proceedings of the IEEE Engineering in Medicine and Biology 27th Annual Conference, Shanghai, China, 1–4 September 2005

28.

Tanifuji T, Ohtomo T, Ohmari D, Ishikawa T (2005) Time-resolved reflectance of an optical pulse in adult heads based on finite difference time domain (FDTD) analysis. Opt Rev 12:42–45CrossRef

29.

Paris F, Canas J (1997) Boundary element method: fundamentals and applications. Oxford University Press, Oxford

30.

Sovizi M, Massudi R (2007) Study of thermal effects, considering birefringence, on phase distortion of beam in a side pumped Nd:YAG rod using BEM. Opt Commun 275:206–212CrossRef

31.

Srinivasan S, Pogue BW, Carpenter C, Yalavarthy PK, Paulsen K (2007) A boundary element approach for image-guided near-infrared absorption and scatter estimation. Med Phys 34:4545–4557PubMedCrossRef

32.

Ansari MA, Massudi R (2009) Study of light propagation in Asian and Caucasian skins by means of the boundary element method. Opt Lasers Eng 47:965–970CrossRef

33.

Patterson MS, Chance B, Wilson BC (1989) Time resolved reflectance and transmittance for the noninvasive measurement of tissue optical properties. Appl Opt 28:2331–2336PubMedCrossRef

34.

Rath P, Mishra SC, Mahanta P, Saha UK, Mitra K (2003) Discrete transfer method applied to transient radiative transfer problems in participating medium. Numer Heat Transfer A 44:183–197CrossRef

35.

Okutucu T, Yener Y (2006) Radiative transfer in participating media with collimated short-pulse Gaussian irradiation. J Phys D Appl Phys 39:1976–1983CrossRef

36.

Boulanger J, Charette A (2005) Numerical developments for short-pulsed near infra-red laser spectroscopy. Part I: direct treatment. J Quant Spectrosc Radiat Transfer 91:189–209CrossRef

Title: Study of short-pulse laser propagation in biological tissue by means of the boundary element method
Authors: Mohammad Ali Ansari
Reza Massudi
Publication date: 01-07-2011
Publisher: Springer-Verlag
Published in: Lasers in Medical Science / Issue 4/2011
Print ISSN: 0268-8921
Electronic ISSN: 1435-604X
DOI: https://doi.org/10.1007/s10103-010-0872-z

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Study of short-pulse laser propagation in biological tissue by means of the boundary element method

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Please log in to get access to this content

Other articles of this Issue 4/2011

Sealing ability of retrofilling materials following various root-end cavity preparation techniques

Argon ion laser curing depth effect on a composite resin

Effect of a newly synthesized Zn sulfophthalocyanine derivative on cell morphology, viability, proliferation, and cytotoxicity in a human lung cancer cell line (A549)

Evaluation of the osteogenic effect of low-level laser therapy (808 nm and 660 nm) on bone defects induced in the femurs of female rats submitted to ovariectomy

One-year clinical results of Er,Cr:YSGG laser application in addition to scaling and root planing in patients with early to moderate periodontitis

Comparison between cold water immersion therapy (CWIT) and light emitting diode therapy (LEDT) in short-term skeletal muscle recovery after high-intensity exercise in athletes—preliminary results