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European Journal of Clinical Microbiology & Infectious Diseases

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01-06-2021 | Coronavirus | Original Article

Comparison of nine different commercially available molecular assays for detection of SARS-CoV-2 RNA

Authors: Ute Eberle, Clara Wimmer, Ingrid Huber, Antonie Neubauer-Juric, Giuseppe Valenza, Nikolaus Ackermann, Andreas Sing, for the Bavarian SARS-CoV-2-Public Health Laboratory Team

Published in: European Journal of Clinical Microbiology & Infectious Diseases | Issue 6/2021

Abstract

To face the COVID-19 pandemic, the need for fast and reliable diagnostic assays for the detection of SARS-CoV-2 is immense. We describe our laboratory experiences evaluating nine commercially available real-time RT-PCR assays. We found that assays differed considerably in performance and validation before routine use is mandatory.

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Romette JL, Prat CM, Gould EA, de Lamballerie X, Charrel R, Coutard B et al (2018) The European Virus Archive goes global: a growing resource for research. Antivir Res 158:127–134CrossRef

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van Kasteren PB, van der Veer B, van den Brink S, Wijsman L, de Jonge J, van den Brandt A, et al (2020) Comparison of seven commercial RT-PCR diagnostic kits for COVID-19. J Clin Virol 128:104412

Title: Comparison of nine different commercially available molecular assays for detection of SARS-CoV-2 RNA
Authors: Ute Eberle
Clara Wimmer
Ingrid Huber
Antonie Neubauer-Juric
Giuseppe Valenza
Nikolaus Ackermann
Andreas Sing
for the Bavarian SARS-CoV-2-Public Health Laboratory Team
Publication date: 01-06-2021
Publisher: Springer Berlin Heidelberg
Keywords: Coronavirus
SARS-CoV-2
COVID-19
Published in: European Journal of Clinical Microbiology & Infectious Diseases / Issue 6/2021
Print ISSN: 0934-9723
Electronic ISSN: 1435-4373
DOI: https://doi.org/10.1007/s10096-021-04159-9

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Abstract

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