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European Journal of Clinical Microbiology & Infectious Diseases

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01-04-2021 | Sexually Transmitted Infection | Brief Report

Multi-year prevalence and macrolide resistance of Mycoplasma genitalium in clinical samples from a southern Italian hospital

Authors: Abbasciano Angela, Del Prete Raffaele, Romanelli Federica, Mosca Adriana, Santacroce Luigi, Ronga Luigi

Published in: European Journal of Clinical Microbiology & Infectious Diseases | Issue 4/2021

Abstract

The use of azithromycin for the treatment of Mycoplasma genitalium infections has led to resistance to macrolides. From July 2014 to July 2020, 7150 samples were analysed for the detection of sexually transmitted infections at the Policlinico of Bari. A total of 67/7150 samples (0.93%) were positive for MG DNA and 47 samples were analysed for the evaluation of six azithromycin resistance-associated mutations. In 5/47 samples, the A2058G mutation was detected (10.63%). Although the cases of positive MG samples and mutations are low in our reality, diagnostic tests to detect azithromycin resistant-associated genes may provide a convenient way to monitor resistance rate.

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Title: Multi-year prevalence and macrolide resistance of Mycoplasma genitalium in clinical samples from a southern Italian hospital
Authors: Abbasciano Angela
Del Prete Raffaele
Romanelli Federica
Mosca Adriana
Santacroce Luigi
Ronga Luigi
Publication date: 01-04-2021
Publisher: Springer Berlin Heidelberg
Keywords: Sexually Transmitted Infection
Macrolide
Sexually Transmitted Infection
Azithromycin
Sexually Transmitted Infection
Sexually Transmitted Infection
Published in: European Journal of Clinical Microbiology & Infectious Diseases / Issue 4/2021
Print ISSN: 0934-9723
Electronic ISSN: 1435-4373
DOI: https://doi.org/10.1007/s10096-020-04068-3

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